6hmj - Revision history

OCA at 09:46, 9 September 2020

OCA — Wed, 09 Sep 2020 09:46:59 GMT

←Older revision		Revision as of 09:46, 9 September 2020
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	<StructureSection load='6hmj' size='340' side='right'caption='[[6hmj]], [[Resolution\|resolution]] 2.51Å' scene=''>		<StructureSection load='6hmj' size='340' side='right'caption='[[6hmj]], [[Resolution\|resolution]] 2.51Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6hmj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HMJ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6HMJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6hmj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Microsphaera_multipartita Microsphaera multipartita]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HMJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6HMJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6hmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hmj OCA], [http://pdbe.org/6hmj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hmj RCSB], [http://www.ebi.ac.uk/pdbsum/6hmj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hmj ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Namu_4361 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=479431 Microsphaera multipartita])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6hmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hmj OCA], [http://pdbe.org/6hmj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hmj RCSB], [http://www.ebi.ac.uk/pdbsum/6hmj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hmj ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sensory photoreceptor proteins underpin light-dependent adaptations in nature and enable the optogenetic control of organismal behavior and physiology. We identified the bacterial light-oxygen-voltage (LOV) photoreceptor PAL that sequence-specifically binds short RNA stem loops with around 20 nM affinity in blue light and weaker than 1 microM in darkness. A crystal structure rationalizes the unusual receptor architecture of PAL with C-terminal LOV photosensor and N-terminal effector units. The light-activated PAL-RNA interaction can be harnessed to regulate gene expression at the RNA level as a function of light in both bacteria and mammalian cells. The present results elucidate a new signal-transduction paradigm in LOV receptors and conjoin RNA biology with optogenetic regulation, thereby paving the way toward hitherto inaccessible optoribogenetic modalities.
		+
		+	A blue light receptor that mediates RNA binding and translational regulation.,Weber AM, Kaiser J, Ziegler T, Pilsl S, Renzl C, Sixt L, Pietruschka G, Moniot S, Kakoti A, Juraschitz M, Schrottke S, Lledo Bryant L, Steegborn C, Bittl R, Mayer G, Moglich A Nat Chem Biol. 2019 Nov;15(11):1085-1092. doi: 10.1038/s41589-019-0346-y. Epub, 2019 Aug 26. PMID:31451761<ref>PMID:31451761</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6hmj" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Microsphaera multipartita]]
	[[Category: Moeglich, A]]		[[Category: Moeglich, A]]
	[[Category: Moniot, S]]		[[Category: Moniot, S]]

OCA at 15:25, 28 August 2019

OCA — Wed, 28 Aug 2019 15:25:09 GMT

←Older revision		Revision as of 15:25, 28 August 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6hmj ~~is ON HOLD until Paper Publication~~	+	==Structure of an RNA-binding Light-Oxygen-Voltage Receptor==
-		+	<StructureSection load='6hmj' size='340' side='right'caption='[[6hmj]], [[Resolution\|resolution]] 2.51Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6hmj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HMJ FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hmj OCA], [http://pdbe.org/6hmj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hmj RCSB], [http://www.ebi.ac.uk/pdbsum/6hmj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hmj ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Moeglich, A]]
		+	[[Category: Moniot, S]]
		+	[[Category: Ziegler, T]]
		+	[[Category: Light-oxygen-voltage]]
		+	[[Category: Rna binding]]
		+	[[Category: Sensory photoreceptor]]
		+	[[Category: Signaling protein]]

OCA at 06:10, 26 September 2018

OCA — Wed, 26 Sep 2018 06:10:51 GMT

←Older revision		Revision as of 06:10, 26 September 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6hmj is ON HOLD	+	The entry 6hmj is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6hmj" [edit=sysop:move=sysop]

OCA — Wed, 19 Sep 2018 18:14:04 GMT

Protected "6hmj" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:14, 19 September 2018

OCA: New page: '''Unreleased structure''' The entry 6hmj is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 19 Sep 2018 18:14:03 GMT

New page: '''Unreleased structure''' The entry 6hmj is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6hmj is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]