6i1c - Revision history

OCA at 07:35, 1 May 2024

OCA — Wed, 01 May 2024 07:35:16 GMT

←Older revision		Revision as of 07:35, 1 May 2024
Line 3:		Line 3:
	<StructureSection load='6i1c' size='340' side='right'caption='[[6i1c]], [[Resolution\|resolution]] 2.01Å' scene=''>		<StructureSection load='6i1c' size='340' side='right'caption='[[6i1c]], [[Resolution\|resolution]] 2.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6i1c]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chlre Chlre~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1C OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6I1C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6i1c]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6I1C FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~CHLRE_05g243050v5 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=3055 CHLRE])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.01Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6i1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1c OCA], [~~http~~://pdbe.org/6i1c PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6i1c RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6i1c PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6i1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1c OCA], [https://pdbe.org/6i1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6i1c RCSB], [https://www.ebi.ac.uk/pdbsum/6i1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1c ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/A0A2K3DSC9_CHLRE A0A2K3DSC9_CHLRE]
-	Protein disulfide reduction by thioredoxins (TRXs) controls the conformation of enzyme active sites and their multimeric complex formation. TRXs are small oxidoreductases that are broadly conserved in all living organisms. In photosynthetic eukaryotes, TRXs form a large multigenic family, and they have been classified in different types: f, m, x, y, and z types are chloroplastic, while o and h types are located in mitochondria and cytosol. In the model unicellular alga Chlamydomonas reinhardtii, the TRX family contains seven types, with f- and h-types represented by two isozymes. Type-f TRXs interact specifically with targets in the chloroplast, controlling photosynthetic carbon fixation by the Calvin(-)Benson cycle. We solved the crystal structures of TRX f2 and TRX h1 from C. reinhardtii. The systematic comparison of their atomic features revealed a specific conserved electropositive crown around the active site of TRX f, complementary to the electronegative surface of their targets. ~~We postulate that this surface provides specificity to each type of TRX~~.	+

-	Crystal Structure of Chloroplastic Thioredoxin f2 from Chlamydomonas reinhardtii Reveals Distinct Surface Properties.,Lemaire SD, Tedesco D, Crozet P, Michelet L, Fermani S, Zaffagnini M, Henri J Antioxidants (Basel). 2018 Nov 23;7(12). pii: antiox7120171. doi:, 10.3390/antiox7120171. PMID:30477165<ref>PMID:30477165</ref>	+	==See Also==
-		+	*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class~~=~~"pdbe-citations 6i1c" style~~=~~"background-color:#fffaf0;"></div>~~	+
-	~~== References~~ ==	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chlre~~]]	+	[[Category: Chlamydomonas reinhardtii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Crozet, P]]	+	[[Category: Crozet P]]
-	[[Category: Fermani, S]]	+	[[Category: Fermani S]]
-	[[Category: Henri, J]]	+	[[Category: Henri J]]
-	[[Category: Lemaire~~, S D~~]]	+	[[Category: Lemaire SD]]
-	[[Category: Michelet, L]]	+	[[Category: Michelet L]]
-	[[Category: Tedesco, D]]	+	[[Category: Tedesco D]]
-	[[Category: Zaffagnini, M]]	+	[[Category: Zaffagnini M]]
-	~~[[Category: Electron transport]]~~	+
-	~~[[Category: F-type cytosolic thioredoxin oxidized~~]]	+

OCA at 11:06, 2 October 2019

OCA — Wed, 02 Oct 2019 11:06:24 GMT

←Older revision		Revision as of 11:06, 2 October 2019
Line 1:		Line 1:

	==Crystal structure of Chlamydomonas reinhardtii thioredoxin f2==		==Crystal structure of Chlamydomonas reinhardtii thioredoxin f2==
-	<StructureSection load='6i1c' size='340' side='right' caption='[[6i1c]], [[Resolution\|resolution]] 2.01Å' scene=''>	+	<StructureSection load='6i1c' size='340' side='right'caption='[[6i1c]], [[Resolution\|resolution]] 2.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6i1c]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I1C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6i1c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlre Chlre]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I1C FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1c OCA], [http://pdbe.org/6i1c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i1c RCSB], [http://www.ebi.ac.uk/pdbsum/6i1c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1c ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHLRE_05g243050v5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3055 CHLRE])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1c OCA], [http://pdbe.org/6i1c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i1c RCSB], [http://www.ebi.ac.uk/pdbsum/6i1c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1c ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chlre]]
		+	[[Category: Large Structures]]
	[[Category: Crozet, P]]		[[Category: Crozet, P]]
	[[Category: Fermani, S]]		[[Category: Fermani, S]]

OCA at 06:48, 5 December 2018

OCA — Wed, 05 Dec 2018 06:48:04 GMT

←Older revision		Revision as of 06:48, 5 December 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6i1c is ~~ON HOLD~~	+	==Crystal structure of Chlamydomonas reinhardtii thioredoxin f2==
		+	<StructureSection load='6i1c' size='340' side='right' caption='[[6i1c]], [[Resolution\|resolution]] 2.01Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6i1c]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I1C FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1c OCA], [http://pdbe.org/6i1c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i1c RCSB], [http://www.ebi.ac.uk/pdbsum/6i1c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1c ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein disulfide reduction by thioredoxins (TRXs) controls the conformation of enzyme active sites and their multimeric complex formation. TRXs are small oxidoreductases that are broadly conserved in all living organisms. In photosynthetic eukaryotes, TRXs form a large multigenic family, and they have been classified in different types: f, m, x, y, and z types are chloroplastic, while o and h types are located in mitochondria and cytosol. In the model unicellular alga Chlamydomonas reinhardtii, the TRX family contains seven types, with f- and h-types represented by two isozymes. Type-f TRXs interact specifically with targets in the chloroplast, controlling photosynthetic carbon fixation by the Calvin(-)Benson cycle. We solved the crystal structures of TRX f2 and TRX h1 from C. reinhardtii. The systematic comparison of their atomic features revealed a specific conserved electropositive crown around the active site of TRX f, complementary to the electronegative surface of their targets. We postulate that this surface provides specificity to each type of TRX.

-	~~Authors:~~ Lemaire~~, S.D.~~, Tedesco, D., Crozet, P., Michelet, L., Fermani, S., Zaffagnini, M., Henri, J.	+	Crystal Structure of Chloroplastic Thioredoxin f2 from Chlamydomonas reinhardtii Reveals Distinct Surface Properties.,Lemaire SD, Tedesco D, Crozet P, Michelet L, Fermani S, Zaffagnini M, Henri J Antioxidants (Basel). 2018 Nov 23;7(12). pii: antiox7120171. doi:, 10.3390/antiox7120171. PMID:30477165<ref>PMID:30477165</ref>

-	~~Description: Crystal structure~~ of ~~Chlamydomonas reinhardtii thioredoxin f2~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 6i1c" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Crozet, P]]
	[[Category: Fermani, S]]		[[Category: Fermani, S]]
-	[[Category: ~~Zaffagnini~~, M]]	+	[[Category: Henri, J]]
		+	[[Category: Lemaire, S D]]
	[[Category: Michelet, L]]		[[Category: Michelet, L]]
	[[Category: Tedesco, D]]		[[Category: Tedesco, D]]
-	[[Category: ~~Crozet~~, P]]	+	[[Category: Zaffagnini, M]]
-	[[Category: ~~Henri, J~~]]	+	[[Category: Electron transport]]
-	[[Category: ~~Lemaire, S.D~~]]	+	[[Category: F-type cytosolic thioredoxin oxidized]]

OCA: Protected "6i1c" [edit=sysop:move=sysop]

OCA — Wed, 07 Nov 2018 10:36:00 GMT

Protected "6i1c" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:36, 7 November 2018

OCA: New page: '''Unreleased structure''' The entry 6i1c is ON HOLD Authors: Lemaire, S.D., Tedesco, D., Crozet, P., Michelet, L., Fermani, S., Zaffagnini, M., Henri, J. Description: Crystal structur...

OCA — Wed, 07 Nov 2018 10:35:59 GMT

New page: '''Unreleased structure''' The entry 6i1c is ON HOLD Authors: Lemaire, S.D., Tedesco, D., Crozet, P., Michelet, L., Fermani, S., Zaffagnini, M., Henri, J. Description: Crystal structur...

New page

'''Unreleased structure'''

The entry 6i1c is ON HOLD

Authors: Lemaire, S.D., Tedesco, D., Crozet, P., Michelet, L., Fermani, S., Zaffagnini, M., Henri, J.

Description: Crystal structure of Chlamydomonas reinhardtii thioredoxin f2
[[Category: Unreleased Structures]]
[[Category: Fermani, S]]
[[Category: Zaffagnini, M]]
[[Category: Michelet, L]]
[[Category: Tedesco, D]]
[[Category: Crozet, P]]
[[Category: Henri, J]]
[[Category: Lemaire, S.D]]