6i1z - Revision history

OCA at 11:44, 24 January 2024

OCA — Wed, 24 Jan 2024 11:44:46 GMT

←Older revision		Revision as of 11:44, 24 January 2024
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	<StructureSection load='6i1z' size='340' side='right'caption='[[6i1z]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='6i1z' size='340' side='right'caption='[[6i1z]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6i1z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6I1Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6i1z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6I1Z FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">[[~~6i1r~~\|~~6i1r~~]]</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.4Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6i1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1z OCA], [~~http~~://pdbe.org/6i1z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6i1z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6i1z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1z ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6i1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1z OCA], [https://pdbe.org/6i1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6i1z RCSB], [https://www.ebi.ac.uk/pdbsum/6i1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1z ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B4FZ94_MAIZE B4FZ94_MAIZE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Drew, D~~]]	+	[[Category: Zea mays]]
-	[[Category: ~~Gulati, A~~]]	+	[[Category: Drew D]]
-	[[Category: ~~Nji, E]]~~	+	[[Category: Gulati A]]
-	~~[[Category: Qureshi, A~~ A]]	+	[[Category: Nji E]]
-	[[Category: ~~Cmp-sialic acid transporter~~]]	+	[[Category: Qureshi AA]]
-	[[Category: ~~Membrane protein]]~~	+
-	~~[[Category: Nucleotide sugar transporter]]~~	+
-	~~[[Category: Secondary active transporter]]~~	+
-	~~[[Category: Slc35a1~~]]	+

OCA at 22:46, 5 June 2019

OCA — Wed, 05 Jun 2019 22:46:08 GMT

←Older revision		Revision as of 22:46, 5 June 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6i1z is ~~ON HOLD until Paper~~ Publication	+	==Outward facing structure of apo CST==
		+	<StructureSection load='6i1z' size='340' side='right'caption='[[6i1z]], [[Resolution\|resolution]] 3.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6i1z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I1Z FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6i1r\|6i1r]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i1z OCA], [http://pdbe.org/6i1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i1z RCSB], [http://www.ebi.ac.uk/pdbsum/6i1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i1z ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The decoration of secretory glycoproteins and glycolipids with sialic acid is critical to many physiological and pathological processes. Sialyation is dependent on a continuous supply of sialic acid into Golgi organelles in the form of CMP-sialic acid. Translocation of CMP-sialic acid into Golgi is carried out by the CMP-sialic acid transporter (CST). Mutations in human CST are linked to glycosylation disorders, and CST is important for glycopathway engineering, as it is critical for sialyation efficiency of therapeutic glycoproteins. The mechanism of how CMP-sialic acid is recognized and translocated across Golgi membranes in exchange for CMP is poorly understood. Here we have determined the crystal structure of a Zea mays CST in complex with CMP. We conclude that the specificity of CST for CMP-sialic acid is established by the recognition of the nucleotide CMP to such an extent that they are mechanistically capable of both passive and coupled antiporter activity.

-	~~Authors~~:	+	Structural basis for the delivery of activated sialic acid into Golgi for sialyation.,Nji E, Gulati A, Qureshi AA, Coincon M, Drew D Nat Struct Mol Biol. 2019 May 27. pii: 10.1038/s41594-019-0225-y. doi:, 10.1038/s41594-019-0225-y. PMID:31133698<ref>PMID:31133698</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6i1z" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Drew, D]]
		+	[[Category: Gulati, A]]
		+	[[Category: Nji, E]]
		+	[[Category: Qureshi, A A]]
		+	[[Category: Cmp-sialic acid transporter]]
		+	[[Category: Membrane protein]]
		+	[[Category: Nucleotide sugar transporter]]
		+	[[Category: Secondary active transporter]]
		+	[[Category: Slc35a1]]

OCA at 06:18, 14 November 2018

OCA — Wed, 14 Nov 2018 06:18:02 GMT

←Older revision		Revision as of 06:18, 14 November 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6i1z is ON HOLD	+	The entry 6i1z is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6i1z" [edit=sysop:move=sysop]

OCA — Wed, 07 Nov 2018 10:38:23 GMT

Protected "6i1z" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:38, 7 November 2018

OCA: New page: '''Unreleased structure''' The entry 6i1z is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 07 Nov 2018 10:38:21 GMT

New page: '''Unreleased structure''' The entry 6i1z is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6i1z is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]