6ith - Revision history

OCA at 10:52, 14 June 2023

OCA — Wed, 14 Jun 2023 10:52:09 GMT

←Older revision		Revision as of 10:52, 14 June 2023
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	==Structure of the transmembrane domain of syndecan 2 in micelles==		==Structure of the transmembrane domain of syndecan 2 in micelles==
-	<StructureSection load='6ith' size='340' side='right'caption='[[6ith~~]], [[NMR_Ensembles_of_Models \| 15 NMR models~~]]' scene=''>	+	<StructureSection load='6ith' size='340' side='right'caption='[[6ith]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ith]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ITH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ITH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ith]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ITH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ITH FirstGlance]. <br>
-	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SDC2, HSPG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ith OCA], [https://pdbe.org/6ith PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ith RCSB], [https://www.ebi.ac.uk/pdbsum/6ith PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ith ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ith OCA], [~~http~~://pdbe.org/6ith PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ith RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ith PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ith ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/SDC2_HUMAN SDC2_HUMAN]] Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).	+	[https://www.uniprot.org/uniprot/SDC2_HUMAN SDC2_HUMAN] Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kang, C]]	+	[[Category: Kang C]]
-	[[Category: Li, Q]]	+	[[Category: Li Q]]
-	[[Category: Ng~~, H Q]]~~	+	[[Category: Ng HQ]]
-	~~[[Category: Dpc]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Micelle~~]]	+

OCA at 07:06, 27 March 2019

OCA — Wed, 27 Mar 2019 07:06:36 GMT

←Older revision		Revision as of 07:06, 27 March 2019
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	==Structure of the transmembrane domain of syndecan 2 in micelles==		==Structure of the transmembrane domain of syndecan 2 in micelles==
-	<StructureSection load='6ith' size='340' side='right' caption='[[6ith]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>	+	<StructureSection load='6ith' size='340' side='right'caption='[[6ith]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ith]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ITH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ith]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ITH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ith OCA], [http://pdbe.org/6ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ith RCSB], [http://www.ebi.ac.uk/pdbsum/6ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ith ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SDC2, HSPG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ith OCA], [http://pdbe.org/6ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ith RCSB], [http://www.ebi.ac.uk/pdbsum/6ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ith ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Kang, C]]		[[Category: Kang, C]]
	[[Category: Li, Q]]		[[Category: Li, Q]]

OCA at 15:26, 27 February 2019

OCA — Wed, 27 Feb 2019 15:26:22 GMT

←Older revision		Revision as of 15:26, 27 February 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6ith is ~~ON HOLD until Paper~~ Publication	+	==Structure of the transmembrane domain of syndecan 2 in micelles==
		+	<StructureSection load='6ith' size='340' side='right' caption='[[6ith]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6ith]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ITH FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ith OCA], [http://pdbe.org/6ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ith RCSB], [http://www.ebi.ac.uk/pdbsum/6ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ith ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SDC2_HUMAN SDC2_HUMAN]] Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Syndecans are single-span membrane proteins playing important roles in cell-cell and cell-matrix interactions. The transmembrane domain of syndecans is critical for signal transduction across the cell membrane. Here, the structure of the transmembrane domain of syndecan-2 in detergent micelles was investigated using solution NMR spectroscopy. Backbone resonance assignment was obtained, and NMR studies show that the transmembrane domain forms a helix in detergent micelles, which is also supported by the hydrogen and deuterium exchange experiment. A study of the dynamics revealed the rigid structure of the transmembrane domain formed in solution, and paramagnetic relaxation enhancement defined the topology of the transmembrane domain in detergent micelles. This structural analysis may facilitate a better understanding of the role of the syndecan-2 transmembrane domain in signal transduction.

-	~~Authors~~:	+	Secondary structure and topology of the transmembrane domain of Syndecan-2 in detergent micelles.,Li Q, Ng HQ, Kang C FEBS Lett. 2019 Feb 11. doi: 10.1002/1873-3468.13335. PMID:30742705<ref>PMID:30742705</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 6ith" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Kang, C]]
		+	[[Category: Li, Q]]
		+	[[Category: Ng, H Q]]
		+	[[Category: Dpc]]
		+	[[Category: Membrane protein]]
		+	[[Category: Micelle]]

OCA at 04:54, 21 February 2019

OCA — Thu, 21 Feb 2019 04:54:40 GMT

←Older revision		Revision as of 04:54, 21 February 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6ith is ON HOLD	+	The entry 6ith is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6ith" [edit=sysop:move=sysop]

OCA — Sun, 02 Dec 2018 18:58:55 GMT

Protected "6ith" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:58, 2 December 2018

OCA: New page: '''Unreleased structure''' The entry 6ith is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Sun, 02 Dec 2018 18:58:54 GMT

New page: '''Unreleased structure''' The entry 6ith is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6ith is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]