6iya - Revision history

OCA at 09:55, 22 November 2023

OCA — Wed, 22 Nov 2023 09:55:02 GMT

←Older revision		Revision as of 09:55, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='6iya' size='340' side='right'caption='[[6iya]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='6iya' size='340' side='right'caption='[[6iya]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6iya]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Sheon Sheon~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IYA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6IYA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6iya]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_oneidensis_MR-1 Shewanella oneidensis MR-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IYA FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~SO_1445 (~~[~~http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=211586 SHEON])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6iya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iya OCA], [~~http~~://pdbe.org/6iya PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6iya RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6iya PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6iya ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iya OCA], [https://pdbe.org/6iya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iya RCSB], [https://www.ebi.ac.uk/pdbsum/6iya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iya ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8EGZ2_SHEON Q8EGZ2_SHEON]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Sheon~~]]	+	[[Category: Shewanella oneidensis MR-1]]
-	[[Category: Li, F]]	+	[[Category: Li F]]
-	[[Category: Liu, L]]	+	[[Category: Liu L]]
-	[[Category: Zhang, X]]	+	[[Category: Zhang X]]
-	[[Category: Zhao, R]]	+	[[Category: Zhao R]]
-	~~[[Category: Antitoxin]]~~	+
-	~~[[Category: Dna binding]]~~	+
-	~~[[Category: Rhh~~]]	+

OCA at 06:16, 7 August 2019

OCA — Wed, 07 Aug 2019 06:16:50 GMT

←Older revision		Revision as of 06:16, 7 August 2019
Line 1:		Line 1:

	==Structure of the DNA binding domain of antitoxin CopASO==		==Structure of the DNA binding domain of antitoxin CopASO==
-	<StructureSection load='6iya' size='340' side='right' caption='[[6iya]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='6iya' size='340' side='right'caption='[[6iya]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6iya]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IYA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IYA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6iya]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sheon Sheon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IYA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IYA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iya OCA], [http://pdbe.org/6iya PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iya RCSB], [http://www.ebi.ac.uk/pdbsum/6iya PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iya ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SO_1445 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=211586 SHEON])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iya OCA], [http://pdbe.org/6iya PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iya RCSB], [http://www.ebi.ac.uk/pdbsum/6iya PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iya ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Toxin-antitoxin (TA) systems play critical roles in the environment adaptation of bacteria. Allosteric coupling between the N-terminal DNA-binding domain and the C-terminal toxin-binding domain of antitoxins contributes to conditional cooperativity in the functioning of type II TA. Herein, using circular dichroism (CD), nuclear magnetic resonance (NMR), X-ray crystallography, and size exclusion chromatography (SEC), the structure and DNA binding of CopASO, a newly identified type II antitoxin in Shewanella oneidensis, were investigated. Our data show that CopASO is a typical RHH antitoxin with an ordered N-terminal domain and a disordered C-terminal domain, and furthermore indicate that the C-terminal domain facilitates DNA binding of the N-terminal domain, which in turn induces the C-terminal domain to fold and associate.
		+
		+	Structure and allosteric coupling of type antitoxin CopASO.,Zhao R, Li Q, Zhang J, Li F, Yao J, Zhang J, Liu L, Wang X, Zhang X Biochem Biophys Res Commun. 2019 Jul 5;514(4):1122-1127. doi:, 10.1016/j.bbrc.2019.05.049. Epub 2019 May 14. PMID:31101334<ref>PMID:31101334</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6iya" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Sheon]]
	[[Category: Li, F]]		[[Category: Li, F]]
	[[Category: Liu, L]]		[[Category: Liu, L]]

OCA at 12:13, 16 January 2019

OCA — Wed, 16 Jan 2019 12:13:01 GMT

←Older revision		Revision as of 12:13, 16 January 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6iya ~~is ON HOLD~~	+	==Structure of the DNA binding domain of antitoxin CopASO==
-		+	<StructureSection load='6iya' size='340' side='right' caption='[[6iya]], [[Resolution\|resolution]] 3.00Å' scene=''>
-	~~Authors~~: ~~Zhao~~, R., ~~Li, F~~., ~~Liu~~, L., ~~Zhang, X~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6iya]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IYA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IYA FirstGlance]. <br>
-	~~Description: Structure of the DNA binding domain of antitoxin CopASO~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iya OCA], [http://pdbe.org/6iya PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iya RCSB], [http://www.ebi.ac.uk/pdbsum/6iya PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iya ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Li, F]]
	[[Category: Liu, L]]		[[Category: Liu, L]]
	[[Category: Zhang, X]]		[[Category: Zhang, X]]
	[[Category: Zhao, R]]		[[Category: Zhao, R]]
-	[[Category: ~~Li, F~~]]	+	[[Category: Antitoxin]]
		+	[[Category: Dna binding]]
		+	[[Category: Rhh]]

OCA: Protected "6iya" [edit=sysop:move=sysop]

OCA — Wed, 19 Dec 2018 06:31:04 GMT

Protected "6iya" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:31, 19 December 2018

OCA: New page: '''Unreleased structure''' The entry 6iya is ON HOLD Authors: Zhao, R., Li, F., Liu, L., Zhang, X. Description: Structure of the DNA binding domain of antitoxin CopASO [[Category: Unre...

OCA — Wed, 19 Dec 2018 06:31:03 GMT

New page: '''Unreleased structure''' The entry 6iya is ON HOLD Authors: Zhao, R., Li, F., Liu, L., Zhang, X. Description: Structure of the DNA binding domain of antitoxin CopASO [[Category: Unre...

New page

'''Unreleased structure'''

The entry 6iya is ON HOLD

Authors: Zhao, R., Li, F., Liu, L., Zhang, X.

Description: Structure of the DNA binding domain of antitoxin CopASO
[[Category: Unreleased Structures]]
[[Category: Liu, L]]
[[Category: Zhang, X]]
[[Category: Zhao, R]]
[[Category: Li, F]]