6j0o - Revision history

OCA at 10:36, 27 March 2024

OCA — Wed, 27 Mar 2024 10:36:12 GMT

←Older revision		Revision as of 10:36, 27 March 2024
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	==Crystal structure of CERT START domain in complex with compound SC1==		==Crystal structure of CERT START domain in complex with compound SC1==
-	<StructureSection load='6j0o' size='340' side='right' caption='[[6j0o]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='6j0o' size='340' side='right'caption='[[6j0o]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6j0o]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J0O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6J0O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6j0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J0O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=XAF:2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol'>XAF</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5zyg\|5zyg]], [[5zyh\|5zyh]], [[5zyi\|5zyi]], [[5zyj\|5zyj]], [[5zyk\|5zyk]], [[5zyl\|5zyl]], [[5zym\|5zym]], [[6iez\|6iez]], [[6if0\|6if0]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=XAF:2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol'>XAF</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CERT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j0o OCA], [https://pdbe.org/6j0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j0o RCSB], [https://www.ebi.ac.uk/pdbsum/6j0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j0o ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6j0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j0o OCA], [~~http~~://pdbe.org/6j0o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6j0o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6j0o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6j0o ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~C43BP_HUMAN C43BP_HUMAN]~~] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>	+	[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Egawa, D]]	+	[[Category: Large Structures]]
-	[[Category: Hanada, K]]	+	[[Category: Egawa D]]
-	[[Category: Hanzawa, H]]	+	[[Category: Hanada K]]
-	[[Category: Kawasaki, S]]	+	[[Category: Hanzawa H]]
-	[[Category: Kobayashi, S]]	+	[[Category: Kawasaki S]]
-	[[Category: Kumagai, K]]	+	[[Category: Kobayashi S]]
-	[[Category: Nakao, N]]	+	[[Category: Kumagai K]]
-	[[Category: Sakai, S]]	+	[[Category: Nakao N]]
-	[[Category: Suzuki, M]]	+	[[Category: Sakai S]]
-	[[Category: Ueno, M]]	+	[[Category: Suzuki M]]
-	~~[[Category: Cert]]~~	+	[[Category: Ueno M]]
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Lipid transport]]~~	+
-	~~[[Category: Ph]]~~	+
-	~~[[Category: Start~~]]	+

OCA at 08:29, 6 March 2019

OCA — Wed, 06 Mar 2019 08:29:07 GMT

←Older revision		Revision as of 08:29, 6 March 2019
Line 1:		Line 1:

	==Crystal structure of CERT START domain in complex with compound SC1==		==Crystal structure of CERT START domain in complex with compound SC1==
-	<StructureSection load='6j0o' size='340' side='right' caption='[[6j0o]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='6j0o' size='340' side='right' caption='[[6j0o]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6j0o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J0O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6j0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J0O FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=XAF:2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol'>XAF</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=XAF:2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol'>XAF</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5zyg\|5zyg]], [[5zyh\|5zyh]], [[5zyi\|5zyi]], [[5zyj\|5zyj]], [[5zyk\|5zyk]], [[5zyl\|5zyl]], [[5zym\|5zym]], [[6iez\|6iez]], [[6if0\|6if0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5zyg\|5zyg]], [[5zyh\|5zyh]], [[5zyi\|5zyi]], [[5zyj\|5zyj]], [[5zyk\|5zyk]], [[5zyl\|5zyl]], [[5zym\|5zym]], [[6iez\|6iez]], [[6if0\|6if0]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CERT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j0o OCA], [http://pdbe.org/6j0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j0o RCSB], [http://www.ebi.ac.uk/pdbsum/6j0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j0o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j0o OCA], [http://pdbe.org/6j0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j0o RCSB], [http://www.ebi.ac.uk/pdbsum/6j0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j0o ProSAT]</span></td></tr>
	</table>		</table>
Line 14:		Line 15:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Egawa, D]]		[[Category: Egawa, D]]
	[[Category: Hanada, K]]		[[Category: Hanada, K]]

OCA at 15:26, 27 February 2019

OCA — Wed, 27 Feb 2019 15:26:48 GMT

←Older revision		Revision as of 15:26, 27 February 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6j0o ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of CERT START domain in complex with compound SC1==
-		+	<StructureSection load='6j0o' size='340' side='right' caption='[[6j0o]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~Authors~~: ~~Suzuki, M~~., ~~Nakao~~, N., ~~Ueno~~, M., ~~Sakai~~, S., ~~Egawa~~, D., ~~Hanzawa, H~~., ~~Kawasaki, S~~., ~~Kumagai, K~~., ~~Kobayashi, S~~., ~~Hanada, K~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6j0o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J0O FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of CERT~~ START domain in ~~complex with compound SC1~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=XAF:2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol'>XAF</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5zyg\|5zyg]], [[5zyh\|5zyh]], [[5zyi\|5zyi]], [[5zyj\|5zyj]], [[5zyk\|5zyk]], [[5zyl\|5zyl]], [[5zym\|5zym]], [[6iez\|6iez]], [[6if0\|6if0]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j0o OCA], [http://pdbe.org/6j0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j0o RCSB], [http://www.ebi.ac.uk/pdbsum/6j0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j0o ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/C43BP_HUMAN C43BP_HUMAN]] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Egawa, D]]
		+	[[Category: Hanada, K]]
		+	[[Category: Hanzawa, H]]
		+	[[Category: Kawasaki, S]]
	[[Category: Kobayashi, S]]		[[Category: Kobayashi, S]]
-	[[Category: Hanada, K]]
	[[Category: Kumagai, K]]		[[Category: Kumagai, K]]
		+	[[Category: Nakao, N]]
	[[Category: Sakai, S]]		[[Category: Sakai, S]]
-	[[Category: ~~Nakao~~, ~~N]]~~	+	[[Category: Suzuki, M]]
-	~~[[Category: Egawa, D]]~~	+
-	~~[[Category: Kawasaki, S~~]]	+
	[[Category: Ueno, M]]		[[Category: Ueno, M]]
-	[[Category: ~~Suzuki, M~~]]	+	[[Category: Cert]]
-	[[Category: ~~Hanzawa, H~~]]	+	[[Category: Complex]]
		+	[[Category: Lipid transport]]
		+	[[Category: Ph]]
		+	[[Category: Start]]

OCA at 06:04, 30 January 2019

OCA — Wed, 30 Jan 2019 06:04:14 GMT

←Older revision		Revision as of 06:04, 30 January 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6j0o is ON HOLD	+	The entry 6j0o is ON HOLD until Paper Publication

	Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.		Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
Line 9:		Line 9:
	[[Category: Kobayashi, S]]		[[Category: Kobayashi, S]]
	[[Category: Hanada, K]]		[[Category: Hanada, K]]
-	[[Category: Suzuki, M]]
	[[Category: Kumagai, K]]		[[Category: Kumagai, K]]
	[[Category: Sakai, S]]		[[Category: Sakai, S]]
Line 15:		Line 14:
	[[Category: Egawa, D]]		[[Category: Egawa, D]]
	[[Category: Kawasaki, S]]		[[Category: Kawasaki, S]]
-	[[Category: Hanzawa, H]]
	[[Category: Ueno, M]]		[[Category: Ueno, M]]
		+	[[Category: Suzuki, M]]
		+	[[Category: Hanzawa, H]]

OCA: Protected "6j0o" [edit=sysop:move=sysop]

OCA — Wed, 02 Jan 2019 04:50:59 GMT

Protected "6j0o" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:50, 2 January 2019

OCA: New page: '''Unreleased structure''' The entry 6j0o is ON HOLD Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K. D...

OCA — Wed, 02 Jan 2019 04:50:58 GMT

New page: '''Unreleased structure''' The entry 6j0o is ON HOLD Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K. D...

New page

'''Unreleased structure'''

The entry 6j0o is ON HOLD

Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.

Description: Crystal structure of CERT START domain in complex with compound SC1
[[Category: Unreleased Structures]]
[[Category: Kobayashi, S]]
[[Category: Hanada, K]]
[[Category: Suzuki, M]]
[[Category: Kumagai, K]]
[[Category: Sakai, S]]
[[Category: Nakao, N]]
[[Category: Egawa, D]]
[[Category: Kawasaki, S]]
[[Category: Hanzawa, H]]
[[Category: Ueno, M]]