6j1i - Revision history

OCA at 09:57, 22 November 2023

OCA — Wed, 22 Nov 2023 09:57:54 GMT

←Older revision		Revision as of 09:57, 22 November 2023
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	<StructureSection load='6j1i' size='340' side='right'caption='[[6j1i]], [[Resolution\|resolution]] 2.29Å' scene=''>		<StructureSection load='6j1i' size='340' side='right'caption='[[6j1i]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6j1i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J1I OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6J1I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6j1i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J1I FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=COA:COENZYME+A'>COA</scene~~>, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.29Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[6j0p\|6j0p]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6j1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j1i OCA], [~~http~~://pdbe.org/6j1i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6j1i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6j1i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6j1i ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j1i OCA], [https://pdbe.org/6j1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j1i RCSB], [https://www.ebi.ac.uk/pdbsum/6j1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j1i ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O67224_AQUAE O67224_AQUAE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Aquifex aeolicus VF5]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aono, S]]	+	[[Category: Aono S]]
-	[[Category: Muraki, N]]	+	[[Category: Muraki N]]
-	~~[[Category: Biosynthetic protein]]~~	+
-	~~[[Category: Carbon monoxide]]~~	+
-	~~[[Category: Hydrogenase]]~~	+
-	~~[[Category: Maturation~~]]	+

OCA at 06:38, 6 November 2019

OCA — Wed, 06 Nov 2019 06:38:47 GMT

←Older revision		Revision as of 06:38, 6 November 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6j1i is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of HypX from Aquifex aeolicus, A392F-I419F variant==
		+	<StructureSection load='6j1i' size='340' side='right'caption='[[6j1i]], [[Resolution\|resolution]] 2.29Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6j1i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J1I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J1I FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6j0p\|6j0p]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j1i OCA], [http://pdbe.org/6j1i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j1i RCSB], [http://www.ebi.ac.uk/pdbsum/6j1i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j1i ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Several accessory proteins are required for the assembly of the metal centers in hydrogenases. In NiFe-hydrogenases, CO and CN(-) are coordinated to the Fe in the NiFe dinuclear cluster of the active center. Though these diatomic ligands are biosynthesized enzymatically, detail mechanisms of their biosynthesis remain unclear. Here, we report the structural characterization of HypX responsible for CO biosynthesis to assemble the active site of NiFe hydrogenase. CoA is constitutionally bound in HypX. Structural characterization of HypX suggests that the formyl-group transfer will take place from N(10)-formyl-THF to CoA to form formyl-CoA in the N-terminal domain of HypX, followed by decarbonylation of formyl-CoA to produce CO in the C-terminal domain though the direct experimental results are not available yet. The conformation of CoA accommodated in the continuous cavity connecting the N- and C-terminal domains will interconvert between the extended and the folded conformations for HypX catalysis.

-	~~Authors~~:	+	Structural characterization of HypX responsible for CO biosynthesis in the maturation of NiFe-hydrogenase.,Muraki N, Ishii K, Uchiyama S, Itoh SG, Okumura H, Aono S Commun Biol. 2019 Oct 18;2:385. doi: 10.1038/s42003-019-0631-z. eCollection 2019. PMID:31646188<ref>PMID:31646188</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6j1i" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Aono, S]]
		+	[[Category: Muraki, N]]
		+	[[Category: Biosynthetic protein]]
		+	[[Category: Carbon monoxide]]
		+	[[Category: Hydrogenase]]
		+	[[Category: Maturation]]

OCA at 05:23, 6 March 2019

OCA — Wed, 06 Mar 2019 05:23:11 GMT

←Older revision		Revision as of 05:23, 6 March 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6j1i is ON HOLD	+	The entry 6j1i is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6j1i" [edit=sysop:move=sysop]

OCA — Wed, 02 Jan 2019 04:52:52 GMT

Protected "6j1i" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:52, 2 January 2019

OCA: New page: '''Unreleased structure''' The entry 6j1i is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 02 Jan 2019 04:52:50 GMT

New page: '''Unreleased structure''' The entry 6j1i is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6j1i is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]