6jc3 - Revision history

OCA at 10:37, 27 March 2024

OCA — Wed, 27 Mar 2024 10:37:35 GMT

←Older revision		Revision as of 10:37, 27 March 2024
Line 3:		Line 3:
	<SX load='6jc3' size='340' side='right' viewer='molstar' caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>		<SX load='6jc3' size='340' side='right' viewer='molstar' caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Avian_paramyxovirus_serotype_i~~ Avian ~~paramyxovirus serotype i~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Avian_orthoavulavirus_1 Avian orthoavulavirus 1] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">NP, ~~N (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=11176 Avian Paramyxovirus Serotype I])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 4.8Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jc3 OCA], [~~http~~://pdbe.org/6jc3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6jc3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6jc3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6jc3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jc3 OCA], [https://pdbe.org/6jc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jc3 RCSB], [https://www.ebi.ac.uk/pdbsum/6jc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jc3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/D6R3F6_9MONO D6R3F6_9MONO]] Encapsidates the genome, protecting it from nucleases.[RuleBase:RU361245]	+	[https://www.uniprot.org/uniprot/D6R3F6_9MONO D6R3F6_9MONO] Encapsidates the genome, protecting it from nucleases.[RuleBase:RU361245]
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Non-segmented negative-strand RNA viruses, such as measles, ebola and Newcastle disease viruses (NDV), encapsidate viral genomic RNAs into helical nucleocapsids, which serve as the template for viral replication and transcription. Here, the clam-shaped nucleocapsid structure, where the NDV viral genome is sequestered, was determined at 4.8 A resolution by cryo-electron microscopy. The clam-shaped structure is composed of two single-turn spirals packed in a back-to-back mode. This tightly packed structure functions as a seed for the assembly of a nucleocapsid from both directions, facilitating the growth of double-headed filaments with two separate RNA strings inside. Disruption of this structure by mutations in its loop interface yielded a single-headed unfunctional filament.	+

-	Self-capping of nucleoprotein filaments protects the Newcastle disease virus genome.,Song X, Shan H, Zhu Y, Hu S, Xue L, Chen Y, Ding W, Niu T, Gu J, Ouyang S, Shen QT, Liu ZJ Elife. 2019 Jul 10;8. pii: 45057. doi: 10.7554/eLife.45057. PMID:31290740<ref>PMID:31290740</ref>	+	==See Also==
-		+	*[[Nucleoprotein 3D structures\|Nucleoprotein 3D structures]]
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 6jc3" style="background-color:#fffaf0;"></div>~~	+
-	== ~~References~~ ==	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: Avian ~~paramyxovirus serotype i~~]]	+	[[Category: Avian orthoavulavirus 1]]
		+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ding, W]]	+	[[Category: Ding W]]
-	[[Category: Liu~~, Z J~~]]	+	[[Category: Liu ZJ]]
-	[[Category: Ouyang, S]]	+	[[Category: Ouyang S]]
-	[[Category: Shan, H]]	+	[[Category: Shan H]]
-	[[Category: Shen~~, Q T~~]]	+	[[Category: Shen QT]]
-	[[Category: Song, X]]	+	[[Category: Song X]]
-	[[Category: Zhu, Y]]	+	[[Category: Zhu Y]]
-	~~[[Category: Nuclear protein]]~~	+
-	~~[[Category: Nuclear protein-rna complex]]~~	+
-	~~[[Category: Self-capping helical structure complex~~]]	+

OCA at 02:05, 11 April 2020

OCA — Sat, 11 Apr 2020 02:05:21 GMT

←Older revision		Revision as of 02:05, 11 April 2020
Line 3:		Line 3:
	<SX load='6jc3' size='340' side='right' viewer='molstar' caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>		<SX load='6jc3' size='340' side='right' viewer='molstar' caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_paramyxovirus_serotype_i Avian paramyxovirus serotype i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_paramyxovirus_serotype_i Avian paramyxovirus serotype i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NP, N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11176 Avian Paramyxovirus Serotype I])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NP, N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11176 Avian Paramyxovirus Serotype I])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jc3 OCA], [http://pdbe.org/6jc3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jc3 RCSB], [http://www.ebi.ac.uk/pdbsum/6jc3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jc3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jc3 OCA], [http://pdbe.org/6jc3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jc3 RCSB], [http://www.ebi.ac.uk/pdbsum/6jc3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jc3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 22:15, 6 March 2020

OCA — Fri, 06 Mar 2020 22:15:48 GMT

←Older revision		Revision as of 22:15, 6 March 2020
Line 1:		Line 1:

	==The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus==		==The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus==
-	<~~StructureSection~~ load='6jc3' size='340' side='right'caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>	+	<SX load='6jc3' size='340' side='right' viewer='molstar' caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_paramyxovirus_serotype_i Avian paramyxovirus serotype i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_paramyxovirus_serotype_i Avian paramyxovirus serotype i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>
Line 21:		Line 21:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Avian paramyxovirus serotype i]]		[[Category: Avian paramyxovirus serotype i]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 17:22, 14 August 2019

OCA — Wed, 14 Aug 2019 17:22:08 GMT

←Older revision		Revision as of 17:22, 14 August 2019
Line 3:		Line 3:
	<StructureSection load='6jc3' size='340' side='right'caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>		<StructureSection load='6jc3' size='340' side='right'caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_paramyxovirus_serotype_i Avian paramyxovirus serotype i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jc3 OCA], [http://pdbe.org/6jc3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jc3 RCSB], [http://www.ebi.ac.uk/pdbsum/6jc3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jc3 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NP, N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11176 Avian Paramyxovirus Serotype I])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jc3 OCA], [http://pdbe.org/6jc3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jc3 RCSB], [http://www.ebi.ac.uk/pdbsum/6jc3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jc3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Avian paramyxovirus serotype i]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Ding, W]]		[[Category: Ding, W]]

OCA at 05:51, 7 August 2019

OCA — Wed, 07 Aug 2019 05:51:46 GMT

←Older revision		Revision as of 05:51, 7 August 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	The ~~entry~~ 6jc3 is ~~ON HOLD until Paper~~ Publication	+	==The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus==
		+	<StructureSection load='6jc3' size='340' side='right'caption='[[6jc3]], [[Resolution\|resolution]] 4.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6jc3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JC3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JC3 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jc3 OCA], [http://pdbe.org/6jc3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jc3 RCSB], [http://www.ebi.ac.uk/pdbsum/6jc3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jc3 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/D6R3F6_9MONO D6R3F6_9MONO]] Encapsidates the genome, protecting it from nucleases.[RuleBase:RU361245]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Non-segmented negative-strand RNA viruses, such as measles, ebola and Newcastle disease viruses (NDV), encapsidate viral genomic RNAs into helical nucleocapsids, which serve as the template for viral replication and transcription. Here, the clam-shaped nucleocapsid structure, where the NDV viral genome is sequestered, was determined at 4.8 A resolution by cryo-electron microscopy. The clam-shaped structure is composed of two single-turn spirals packed in a back-to-back mode. This tightly packed structure functions as a seed for the assembly of a nucleocapsid from both directions, facilitating the growth of double-headed filaments with two separate RNA strings inside. Disruption of this structure by mutations in its loop interface yielded a single-headed unfunctional filament.

-	~~Authors: Xiyong, S~~., ~~Hong~~, S., ~~Yanping~~, Z., ~~Wei~~, D., ~~Songying~~, O., ~~Qing-Tao~~, S., ~~Zhi-Jie~~, L.	+	Self-capping of nucleoprotein filaments protects the Newcastle disease virus genome.,Song X, Shan H, Zhu Y, Hu S, Xue L, Chen Y, Ding W, Niu T, Gu J, Ouyang S, Shen QT, Liu ZJ Elife. 2019 Jul 10;8. pii: 45057. doi: 10.7554/eLife.45057. PMID:31290740<ref>PMID:31290740</ref>

-	~~Description: The Cryo-EM structure~~ of ~~nucleoprotein-RNA complex~~ of ~~Newcastle disease virus~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: ~~Zhi-Jie~~, L]]	+	<div class="pdbe-citations 6jc3" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Songying~~, O]]	+	== References ==
-	[[Category: ~~Hong~~, S]]	+	<references/>
-	[[Category: ~~Qing-Tao~~, S]]	+	__TOC__
-	[[Category: ~~Xiyong~~, S]]	+	</StructureSection>
-	[[Category: ~~Yanping~~, Z]]	+	[[Category: Large Structures]]
-	[[Category: ~~Wei~~, D]]	+	[[Category: Ding, W]]
		+	[[Category: Liu, Z J]]
		+	[[Category: Ouyang, S]]
		+	[[Category: Shan, H]]
		+	[[Category: Shen, Q T]]
		+	[[Category: Song, X]]
		+	[[Category: Zhu, Y]]
		+	[[Category: Nuclear protein]]
		+	[[Category: Nuclear protein-rna complex]]
		+	[[Category: Self-capping helical structure complex]]

OCA at 03:55, 17 April 2019

OCA — Wed, 17 Apr 2019 03:55:14 GMT

←Older revision		Revision as of 03:55, 17 April 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6jc3 is ON HOLD	+	The entry 6jc3 is ON HOLD until Paper Publication

	Authors: Xiyong, S., Hong, S., Yanping, Z., Wei, D., Songying, O., Qing-Tao, S., Zhi-Jie, L.		Authors: Xiyong, S., Hong, S., Yanping, Z., Wei, D., Songying, O., Qing-Tao, S., Zhi-Jie, L.
Line 7:		Line 7:
	Description: The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus		Description: The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Qing-Tao, S]]
-	[[Category: Xiyong, S]]
	[[Category: Zhi-Jie, L]]		[[Category: Zhi-Jie, L]]
	[[Category: Songying, O]]		[[Category: Songying, O]]
	[[Category: Hong, S]]		[[Category: Hong, S]]
		+	[[Category: Qing-Tao, S]]
		+	[[Category: Xiyong, S]]
	[[Category: Yanping, Z]]		[[Category: Yanping, Z]]
	[[Category: Wei, D]]		[[Category: Wei, D]]

OCA: Protected "6jc3" [edit=sysop:move=sysop]

OCA — Wed, 13 Feb 2019 07:20:40 GMT

Protected "6jc3" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:20, 13 February 2019

OCA: New page: '''Unreleased structure''' The entry 6jc3 is ON HOLD Authors: Xiyong, S., Hong, S., Yanping, Z., Wei, D., Songying, O., Qing-Tao, S., Zhi-Jie, L. Description: The Cryo-EM structure of ...

OCA — Wed, 13 Feb 2019 07:20:38 GMT

New page: '''Unreleased structure''' The entry 6jc3 is ON HOLD Authors: Xiyong, S., Hong, S., Yanping, Z., Wei, D., Songying, O., Qing-Tao, S., Zhi-Jie, L. Description: The Cryo-EM structure of ...

New page

'''Unreleased structure'''

The entry 6jc3 is ON HOLD

Authors: Xiyong, S., Hong, S., Yanping, Z., Wei, D., Songying, O., Qing-Tao, S., Zhi-Jie, L.

Description: The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus
[[Category: Unreleased Structures]]
[[Category: Qing-Tao, S]]
[[Category: Xiyong, S]]
[[Category: Zhi-Jie, L]]
[[Category: Songying, O]]
[[Category: Hong, S]]
[[Category: Yanping, Z]]
[[Category: Wei, D]]