6jce - Revision history

OCA at 10:52, 14 June 2023

OCA — Wed, 14 Jun 2023 10:52:29 GMT

←Older revision		Revision as of 10:52, 14 June 2023
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	==NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes==		==NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes==
-	<StructureSection load='6jce' size='340' side='right'caption='[[6jce~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='6jce' size='340' side='right'caption='[[6jce]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6jce]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JCE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6JCE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jce]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JCE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6jce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jce OCA], [~~http~~://pdbe.org/6jce PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6jce RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6jce PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6jce ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jce OCA], [https://pdbe.org/6jce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jce RCSB], [https://www.ebi.ac.uk/pdbsum/6jce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jce ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bakalar, B]]	+	[[Category: Synthetic construct]]
-	[[Category: Maity, A]]	+	[[Category: Bakalar B]]
-	[[Category: Mechulam, Y]]	+	[[Category: Maity A]]
-	[[Category: Phan~~, A T~~]]	+	[[Category: Mechulam Y]]
-	[[Category: Schmitt, E]]	+	[[Category: Phan AT]]
-	[[Category: Vandana~~, J J~~]]	+	[[Category: Schmitt E]]
-	[[Category: Winnerdy~~, F R]]~~	+	[[Category: Vandana JJ]]
-	~~[[Category: Dna]]~~	+	[[Category: Winnerdy FR]]
-	~~[[Category: G-quadruplex]]~~	+
-	~~[[Category: Hybrid]]~~	+
-	~~[[Category: Left-handed]]~~	+
-	~~[[Category: Z-g4~~]]	+

OCA at 05:44, 10 July 2019

OCA — Wed, 10 Jul 2019 05:44:48 GMT

←Older revision		Revision as of 05:44, 10 July 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6jce is ~~ON HOLD until Paper~~ Publication	+	==NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes==
		+	<StructureSection load='6jce' size='340' side='right'caption='[[6jce]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6jce]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JCE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JCE FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jce OCA], [http://pdbe.org/6jce PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jce RCSB], [http://www.ebi.ac.uk/pdbsum/6jce PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jce ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Analogous to the B- and Z-DNA structures in double-helix DNA, there exist both right- and left-handed quadruple-helix (G-quadruplex) DNA. Numerous conformations of right-handed and a few left-handed G-quadruplexes were previously observed, yet they were always identified separately. Here, we present the NMR solution and X-ray crystal structures of a right- and left-handed hybrid G-quadruplex. The structure reveals a stacking interaction between two G-quadruplex blocks with different helical orientations and displays features of both right- and left-handed G-quadruplexes. An analysis of loop mutations suggests that single-nucleotide loops are preferred or even required for the left-handed G-quadruplex formation. The discovery of a right- and left-handed hybrid G-quadruplex further expands the polymorphism of G-quadruplexes and is potentially useful in designing a left-to-right junction in G-quadruplex engineering.

-	~~Authors:~~ Winnerdy~~, F.R.~~, Bakalar, B., Maity, A., Vandana~~, J.J.~~, Mechulam, Y., Schmitt, E., Phan~~, A~~.T.	+	NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.,Winnerdy FR, Bakalar B, Maity A, Vandana JJ, Mechulam Y, Schmitt E, Phan AT Nucleic Acids Res. 2019 Jun 19. pii: 5520578. doi: 10.1093/nar/gkz349. PMID:31216034<ref>PMID:31216034</ref>

-	~~Description: NMR solution and X-ray crystal structures~~ of ~~a DNA containing both right~~-~~and left~~-~~handed parallel-stranded G-quadruplexes~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: ~~Schmitt~~, ~~E]]~~	+	<div class="pdbe-citations 6jce" style="background-color:#fffaf0;"></div>
-	~~[[Category: Vandana, J.J~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Bakalar, B]]
	[[Category: Maity, A]]		[[Category: Maity, A]]
-	[[Category: Phan, A.T]]
-	[[Category: Winnerdy, F.R]]
	[[Category: Mechulam, Y]]		[[Category: Mechulam, Y]]
-	[[Category: ~~Bakalar~~, B]]	+	[[Category: Phan, A T]]
		+	[[Category: Schmitt, E]]
		+	[[Category: Vandana, J J]]
		+	[[Category: Winnerdy, F R]]
		+	[[Category: Dna]]
		+	[[Category: G-quadruplex]]
		+	[[Category: Hybrid]]
		+	[[Category: Left-handed]]
		+	[[Category: Z-g4]]

OCA at 04:57, 21 February 2019

OCA — Thu, 21 Feb 2019 04:57:41 GMT

←Older revision		Revision as of 04:57, 21 February 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6jce is ON HOLD	+	The entry 6jce is ON HOLD until Paper Publication

	Authors: Winnerdy, F.R., Bakalar, B., Maity, A., Vandana, J.J., Mechulam, Y., Schmitt, E., Phan, A.T.		Authors: Winnerdy, F.R., Bakalar, B., Maity, A., Vandana, J.J., Mechulam, Y., Schmitt, E., Phan, A.T.
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	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Schmitt, E]]		[[Category: Schmitt, E]]
-	[[Category: Mechulam, Y]]
	[[Category: Vandana, J.J]]		[[Category: Vandana, J.J]]
	[[Category: Maity, A]]		[[Category: Maity, A]]
	[[Category: Phan, A.T]]		[[Category: Phan, A.T]]
	[[Category: Winnerdy, F.R]]		[[Category: Winnerdy, F.R]]
		+	[[Category: Mechulam, Y]]
	[[Category: Bakalar, B]]		[[Category: Bakalar, B]]

OCA: Protected "6jce" [edit=sysop:move=sysop]

OCA — Wed, 13 Feb 2019 07:21:56 GMT

Protected "6jce" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:21, 13 February 2019

OCA: New page: '''Unreleased structure''' The entry 6jce is ON HOLD Authors: Winnerdy, F.R., Bakalar, B., Maity, A., Vandana, J.J., Mechulam, Y., Schmitt, E., Phan, A.T. Description: NMR solution and...

OCA — Wed, 13 Feb 2019 07:21:54 GMT

New page: '''Unreleased structure''' The entry 6jce is ON HOLD Authors: Winnerdy, F.R., Bakalar, B., Maity, A., Vandana, J.J., Mechulam, Y., Schmitt, E., Phan, A.T. Description: NMR solution and...

New page

'''Unreleased structure'''

The entry 6jce is ON HOLD

Authors: Winnerdy, F.R., Bakalar, B., Maity, A., Vandana, J.J., Mechulam, Y., Schmitt, E., Phan, A.T.

Description: NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes
[[Category: Unreleased Structures]]
[[Category: Schmitt, E]]
[[Category: Mechulam, Y]]
[[Category: Vandana, J.J]]
[[Category: Maity, A]]
[[Category: Phan, A.T]]
[[Category: Winnerdy, F.R]]
[[Category: Bakalar, B]]