6jmb - Revision history

OCA at 10:15, 22 November 2023

OCA — Wed, 22 Nov 2023 10:15:45 GMT

←Older revision		Revision as of 10:15, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='6jmb' size='340' side='right'caption='[[6jmb]], [[Resolution\|resolution]] 1.39Å' scene=''>		<StructureSection load='6jmb' size='340' side='right'caption='[[6jmb]], [[Resolution\|resolution]] 1.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6jmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Asian_corn_borer Asian corn borer~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JMB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ostrinia_furnacalis Ostrinia furnacalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JMB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMI:ALLOSAMIZOLINE'>AMI</scene>, <scene name='pdbligand=NAA:N-ACETYL-D-ALLOSAMINE'>NAA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.389Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMI:ALLOSAMIZOLINE'>AMI</scene>, <scene name='pdbligand=NAA:N-ACETYL-D-ALLOSAMINE'>NAA</scene>, <scene name='pdbligand=PRD_000468:Allosamidin'>PRD_000468</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmb OCA], [https://pdbe.org/6jmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jmb RCSB], [https://www.ebi.ac.uk/pdbsum/6jmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmb OCA], [https://pdbe.org/6jmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jmb RCSB], [https://www.ebi.ac.uk/pdbsum/6jmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmb ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A482LWB1_OSTFU A0A482LWB1_OSTFU]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The antifungal activity of insect chitinase has rarely been studied. Here, we show that chitinase ChtIV, which is specifically expressed in the midgut of Asian corn borer (Ostrinia furnacalis), has antifungal activity toward phytopathogenic fungi. ChtIV exhibited high stability and mycelial hydrolytic activity in the extreme midgut environment, which has a pH of 10 and is rich in proteases. Hyper-N-glycosylation and reduced electrostatic interactions ensure the stability of ChtIV in the midgut. The structural characteristics of ChtIV are similar to two plant antifungal chitinases but distinct from an insect chitinase for cuticular chitin degradation in both the substrate-binding cleft and auxiliary binding motif. Since the phytopathogenic fungi are those that frequently invade corn, ChtIV may play a role in insect immune system and become a potential pesticide target. The crystal structures of ChtIV and its complexes with penta-N-acetylchitopentaose (a substrate) and allosamidin (an inhibitor) were obtained, which may facilitate rational design of ChtIV inhibitors as agrichemicals.
		+
		+	Structural and biochemical insights into an insect gut-specific chitinase with antifungal activity.,Liu T, Guo X, Bu Y, Zhou Y, Duan Y, Yang Q Insect Biochem Mol Biol. 2020 Apr;119:103326. doi: 10.1016/j.ibmb.2020.103326. , Epub 2020 Jan 20. PMID:31968227<ref>PMID:31968227</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6jmb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Chitinase 3D structures\|Chitinase 3D structures]]		*[[Chitinase 3D structures\|Chitinase 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Asian corn borer]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Liu, T~~]]	+	[[Category: Ostrinia furnacalis]]
-	[[Category: ~~Yang, Q~~]]	+	[[Category: Liu T]]
-	[[Category: ~~Allosamidin]]~~	+	[[Category: Yang Q]]
-	~~[[Category: Chitinase]]~~	+
-	~~[[Category: Group iv]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 10:16, 13 April 2022

OCA — Wed, 13 Apr 2022 10:16:05 GMT

←Older revision		Revision as of 10:16, 13 April 2022
Line 3:		Line 3:
	<StructureSection load='6jmb' size='340' side='right'caption='[[6jmb]], [[Resolution\|resolution]] 1.39Å' scene=''>		<StructureSection load='6jmb' size='340' side='right'caption='[[6jmb]], [[Resolution\|resolution]] 1.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6jmb]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6JMB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JMB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=~~AO3~~:~~ALLOSAMIDIN~~'>~~AO3~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMI:ALLOSAMIZOLINE'>AMI</scene>, <scene name='pdbligand=NAA:N-ACETYL-D-ALLOSAMINE'>NAA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6jmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmb OCA], [~~http~~://pdbe.org/6jmb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6jmb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6jmb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmb OCA], [https://pdbe.org/6jmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jmb RCSB], [https://www.ebi.ac.uk/pdbsum/6jmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmb ProSAT]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Chitinase 3D structures\|Chitinase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:00, 22 April 2020

OCA — Wed, 22 Apr 2020 06:00:19 GMT

←Older revision		Revision as of 06:00, 22 April 2020
Line 3:		Line 3:
	<StructureSection load='6jmb' size='340' side='right'caption='[[6jmb]], [[Resolution\|resolution]] 1.39Å' scene=''>		<StructureSection load='6jmb' size='340' side='right'caption='[[6jmb]], [[Resolution\|resolution]] 1.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6jmb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6JMB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jmb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6JMB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AO3:ALLOSAMIDIN'>AO3</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AO3:ALLOSAMIDIN'>AO3</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6jmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmb OCA], [http://pdbe.org/6jmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jmb RCSB], [http://www.ebi.ac.uk/pdbsum/6jmb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6jmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmb OCA], [http://pdbe.org/6jmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jmb RCSB], [http://www.ebi.ac.uk/pdbsum/6jmb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmb ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Asian corn borer]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Liu, T]]		[[Category: Liu, T]]

OCA at 07:14, 11 March 2020

OCA — Wed, 11 Mar 2020 07:14:36 GMT

←Older revision		Revision as of 07:14, 11 March 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6jmb is ON HOLD until Paper Publication~~	+	==Crystal structure of Ostrinia furnacalis Group IV chitinase in complex with allosamidin==
-		+	<StructureSection load='6jmb' size='340' side='right'caption='[[6jmb]], [[Resolution\|resolution]] 1.39Å' scene=''>
-	~~Authors: Liu, T., Yang, Q.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6jmb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JMB FirstGlance]. <br>
-	~~Description:~~ Crystal structure of Ostrinia furnacalis Group IV chitinase in complex with allosamidin	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AO3:ALLOSAMIDIN'>AO3</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmb OCA], [http://pdbe.org/6jmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jmb RCSB], [http://www.ebi.ac.uk/pdbsum/6jmb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmb ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Liu, T]]
	[[Category: Yang, Q]]		[[Category: Yang, Q]]
-	[[Category: ~~Liu, T~~]]	+	[[Category: Allosamidin]]
		+	[[Category: Chitinase]]
		+	[[Category: Group iv]]
		+	[[Category: Hydrolase]]

OCA at 04:24, 3 April 2019

OCA — Wed, 03 Apr 2019 04:24:19 GMT

←Older revision		Revision as of 04:24, 3 April 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6jmb is ON HOLD	+	The entry 6jmb is ON HOLD until Paper Publication

	Authors: Liu, T., Yang, Q.		Authors: Liu, T., Yang, Q.

OCA: Protected "6jmb" [edit=sysop:move=sysop]

OCA — Wed, 13 Mar 2019 10:06:04 GMT

Protected "6jmb" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:06, 13 March 2019

OCA: New page: '''Unreleased structure''' The entry 6jmb is ON HOLD Authors: Liu, T., Yang, Q. Description: Crystal structure of Ostrinia furnacalis Group IV chitinase in complex with allosamidin [[C...

OCA — Wed, 13 Mar 2019 10:06:02 GMT

New page: '''Unreleased structure''' The entry 6jmb is ON HOLD Authors: Liu, T., Yang, Q. Description: Crystal structure of Ostrinia furnacalis Group IV chitinase in complex with allosamidin [[C...

New page

'''Unreleased structure'''

The entry 6jmb is ON HOLD

Authors: Liu, T., Yang, Q.

Description: Crystal structure of Ostrinia furnacalis Group IV chitinase in complex with allosamidin
[[Category: Unreleased Structures]]
[[Category: Yang, Q]]
[[Category: Liu, T]]