6jv7 - Revision history

OCA at 10:28, 15 November 2023

OCA — Wed, 15 Nov 2023 10:28:22 GMT

←Older revision		Revision as of 10:28, 15 November 2023
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	==Chimeric Rat C5a==		==Chimeric Rat C5a==
-	<StructureSection load='6jv7' size='340' side='right'caption='[[6jv7]]' scene=''>	+	<StructureSection load='6jv7' size='340' side='right'caption='[[6jv7]], [[Resolution\|resolution]] 1.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JV7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6JV7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jv7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JV7 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6jv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jv7 OCA], [~~http~~://pdbe.org/6jv7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6jv7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6jv7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6jv7 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.309Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALN:NAPHTHALEN-2-YL-3-ALANINE'>ALN</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DAR:D-ARGININE'>DAR</scene>, <scene name='pdbligand=DAS:D-ASPARTIC+ACID'>DAS</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=DGN:D-GLUTAMINE'>DGN</scene>, <scene name='pdbligand=DHI:D-HISTIDINE'>DHI</scene>, <scene name='pdbligand=DIL:D-ISOLEUCINE'>DIL</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=DPN:D-PHENYLALANINE'>DPN</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=DSG:D-ASPARAGINE'>DSG</scene>, <scene name='pdbligand=DSN:D-SERINE'>DSN</scene>, <scene name='pdbligand=DTH:D-THREONINE'>DTH</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=MED:D-METHIONINE'>MED</scene>, <scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZAL:3-CYCLOHEXYL-D-ALANINE'>ZAL</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jv7 OCA], [https://pdbe.org/6jv7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jv7 RCSB], [https://www.ebi.ac.uk/pdbsum/6jv7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jv7 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CO5_RAT CO5_RAT] Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.[UniProtKB:P01031]
		+
		+	==See Also==
		+	*[[Complement C5 3D structures\|Complement C5 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Rattus norvegicus]]
	[[Category: Zuo C]]		[[Category: Zuo C]]

OCA at 05:39, 22 April 2020

OCA — Wed, 22 Apr 2020 05:39:26 GMT

←Older revision		Revision as of 05:39, 22 April 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6jv7 ~~is ON HOLD until Paper Publication~~	+	==Chimeric Rat C5a==
-		+	<StructureSection load='6jv7' size='340' side='right'caption='[[6jv7]]' scene=''>
-	~~Authors~~: ~~Zuo~~, C.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JV7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6JV7 FirstGlance]. <br>
-	~~Description: Chimeric Rat C5a~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6jv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jv7 OCA], [http://pdbe.org/6jv7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jv7 RCSB], [http://www.ebi.ac.uk/pdbsum/6jv7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jv7 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Zuo, C]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Zuo C]]

OCA at 06:28, 2 October 2019

OCA — Wed, 02 Oct 2019 06:28:24 GMT

←Older revision		Revision as of 06:28, 2 October 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6jv7 is ON HOLD	+	The entry 6jv7 is ON HOLD until Paper Publication

	Authors: Zuo, C.		Authors: Zuo, C.

OCA: Protected "6jv7" [edit=sysop:move=sysop]

OCA — Wed, 24 Apr 2019 04:47:08 GMT

Protected "6jv7" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:47, 24 April 2019

OCA: New page: '''Unreleased structure''' The entry 6jv7 is ON HOLD Authors: Zuo, C. Description: Chimeric Rat C5a Category: Unreleased Structures Category: Zuo, C

OCA — Wed, 24 Apr 2019 04:47:06 GMT

New page: '''Unreleased structure''' The entry 6jv7 is ON HOLD Authors: Zuo, C. Description: Chimeric Rat C5a Category: Unreleased Structures Category: Zuo, C

New page

'''Unreleased structure'''

The entry 6jv7 is ON HOLD

Authors: Zuo, C.

Description: Chimeric Rat C5a
[[Category: Unreleased Structures]]
[[Category: Zuo, C]]