6jwd - Revision history

OCA at 10:52, 14 June 2023

OCA — Wed, 14 Jun 2023 10:52:41 GMT

←Older revision		Revision as of 10:52, 14 June 2023
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	<StructureSection load='6jwd' size='340' side='right'caption='[[6jwd]]' scene=''>		<StructureSection load='6jwd' size='340' side='right'caption='[[6jwd]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JWD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6JWD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6jwd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JWD FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6jwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jwd OCA], [~~http~~://pdbe.org/6jwd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6jwd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6jwd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6jwd ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BER:BERBERINE'>BER</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jwd OCA], [https://pdbe.org/6jwd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jwd RCSB], [https://www.ebi.ac.uk/pdbsum/6jwd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jwd ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	G-quadruplexes (G4s) are frequently formed in the promoter regions of oncogenes, considered as promising drug targets for anticancer therapy. Due to high structure similarity of G4s, discovering ligands selectively interacting with only one G4 is extremely difficult. Here, mainly by NMR, we report that colchicine selectively binds to oncogene RET G4-DNA.
		+
		+	Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR.,Wang F, Wang C, Liu Y, Lan W, Han H, Wang R, Huang S, Cao C Chem Commun (Camb). 2020 Feb 18;56(14):2099-2102. doi: 10.1039/d0cc00221f. Epub, 2020 Feb 6. PMID:32025680<ref>PMID:32025680</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6jwd" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Cao C]]		[[Category: Cao C]]

OCA at 05:39, 22 April 2020

OCA — Wed, 22 Apr 2020 05:39:41 GMT

←Older revision		Revision as of 05:39, 22 April 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6jwd is ~~ON HOLD~~	+	==structure of RET G-quadruplex in complex with berberine==
-		+	<StructureSection load='6jwd' size='340' side='right'caption='[[6jwd]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JWD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6JWD FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6jwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jwd OCA], [http://pdbe.org/6jwd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jwd RCSB], [http://www.ebi.ac.uk/pdbsum/6jwd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jwd ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Cao C]]
		+	[[Category: Lan WX]]
		+	[[Category: Li YM]]
		+	[[Category: Liu Y]]
		+	[[Category: Wang C]]
		+	[[Category: Wang F]]
		+	[[Category: Wang RX]]

OCA: Protected "6jwd" [edit=sysop:move=sysop]

OCA — Wed, 01 May 2019 06:56:36 GMT

Protected "6jwd" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:56, 1 May 2019

OCA: New page: '''Unreleased structure''' The entry 6jwd is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 01 May 2019 06:56:35 GMT

New page: '''Unreleased structure''' The entry 6jwd is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6jwd is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]