6k3i - Revision history

OCA at 10:41, 27 March 2024

OCA — Wed, 27 Mar 2024 10:41:01 GMT

←Older revision		Revision as of 10:41, 27 March 2024
Line 3:		Line 3:
	<SX load='6k3i' size='340' side='right' viewer='molstar' caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>		<SX load='6k3i' size='340' side='right' viewer='molstar' caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Salty Salty~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6K3I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6K3I FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6k3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k3i OCA], [~~http~~://pdbe.org/6k3i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6k3i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6k3i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6k3i ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.86Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6k3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k3i OCA], [https://pdbe.org/6k3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6k3i RCSB], [https://www.ebi.ac.uk/pdbsum/6k3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6k3i ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/FLGE_SALTY FLGE_SALTY]
-	Bacterial locomotion by rotating flagella is achieved through the hook, which transmits torque from the motor to the filament. The hook is a tubular structure composed of a single type of protein, yet it adopts a curved shape. To perform its function, it must be simultaneously flexible and torsionally rigid. The molecular mechanism by which chemically identical subunits form such a dynamic structure is unknown. Here, we show the complete structure of the hook from Salmonella enterica in its supercoiled 'curved' state, at 2.9 A resolution. Subunits in the curved hook are grouped into 11 distinctive conformations, each shared along 11 protofilaments. The domains of the elongated hook subunit behave as rigid bodies connected by two hinge regions. The reconstituted model demonstrates how identical subunits can dynamically change conformation by physical interactions while bending. These multiple subunit states contradict the two-state model, which is a key feature of flagellar polymorphism.	+
-		+
-	~~Torque transmission mechanism of the curved bacterial flagellar hook revealed by cryo-EM.,Shibata S, Matsunami H, Aizawa SI, Wolf M Nat Struct Mol Biol. 2019 Sep 30. pii~~: ~~10.1038~~/~~s41594-019-0301-3. doi:, 10.1038~~/~~s41594-019-0301-3~~. ~~PMID:31570877<ref>PMID:31570877</ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.~~S. National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 6k3i" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</SX>		</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Salty~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-	[[Category: Aizawa, S]]	+	[[Category: Aizawa S]]
-	[[Category: Matsunami, H]]	+	[[Category: Matsunami H]]
-	[[Category: Shibata, S]]	+	[[Category: Shibata S]]
-	[[Category: Wolf, M]]	+	[[Category: Wolf M]]
-	~~[[Category: Bacterial]]~~	+
-	~~[[Category: Flagella]]~~	+
-	~~[[Category: Flexible joint]]~~	+
-	~~[[Category: Hook]]~~	+
-	~~[[Category: Motor protein~~]]	+

OCA at 02:19, 11 April 2020

OCA — Sat, 11 Apr 2020 02:19:07 GMT

←Older revision		Revision as of 02:19, 11 April 2020
Line 3:		Line 3:
	<SX load='6k3i' size='340' side='right' viewer='molstar' caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>		<SX load='6k3i' size='340' side='right' viewer='molstar' caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6K3I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6K3I FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6k3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k3i OCA], [http://pdbe.org/6k3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k3i RCSB], [http://www.ebi.ac.uk/pdbsum/6k3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k3i ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6k3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k3i OCA], [http://pdbe.org/6k3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k3i RCSB], [http://www.ebi.ac.uk/pdbsum/6k3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k3i ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:22, 6 March 2020

OCA — Fri, 06 Mar 2020 22:22:21 GMT

←Older revision		Revision as of 22:22, 6 March 2020
Line 1:		Line 1:

	==Salmonella hook in curved state - 66 subunit models==		==Salmonella hook in curved state - 66 subunit models==
-	<~~StructureSection~~ load='6k3i' size='340' side='right'caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>	+	<SX load='6k3i' size='340' side='right' viewer='molstar' caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6K3I FirstGlance]. <br>		<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6K3I FirstGlance]. <br>
Line 18:		Line 18:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Salty]]		[[Category: Salty]]

OCA at 07:21, 16 October 2019

OCA — Wed, 16 Oct 2019 07:21:23 GMT

←Older revision		Revision as of 07:21, 16 October 2019
Line 3:		Line 3:
	<StructureSection load='6k3i' size='340' side='right'caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>		<StructureSection load='6k3i' size='340' side='right'caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Salmonella_typhimurium_(strain_lt2_/_sgsc1412_/_atcc_700720) Salmonella typhimurium (strain lt2 / sgsc1412 / atcc 700720)~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6K3I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6K3I FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6k3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k3i OCA], [http://pdbe.org/6k3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k3i RCSB], [http://www.ebi.ac.uk/pdbsum/6k3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k3i ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6k3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k3i OCA], [http://pdbe.org/6k3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k3i RCSB], [http://www.ebi.ac.uk/pdbsum/6k3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k3i ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial locomotion by rotating flagella is achieved through the hook, which transmits torque from the motor to the filament. The hook is a tubular structure composed of a single type of protein, yet it adopts a curved shape. To perform its function, it must be simultaneously flexible and torsionally rigid. The molecular mechanism by which chemically identical subunits form such a dynamic structure is unknown. Here, we show the complete structure of the hook from Salmonella enterica in its supercoiled 'curved' state, at 2.9 A resolution. Subunits in the curved hook are grouped into 11 distinctive conformations, each shared along 11 protofilaments. The domains of the elongated hook subunit behave as rigid bodies connected by two hinge regions. The reconstituted model demonstrates how identical subunits can dynamically change conformation by physical interactions while bending. These multiple subunit states contradict the two-state model, which is a key feature of flagellar polymorphism.
		+
		+	Torque transmission mechanism of the curved bacterial flagellar hook revealed by cryo-EM.,Shibata S, Matsunami H, Aizawa SI, Wolf M Nat Struct Mol Biol. 2019 Sep 30. pii: 10.1038/s41594-019-0301-3. doi:, 10.1038/s41594-019-0301-3. PMID:31570877<ref>PMID:31570877</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6k3i" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Salty]]
	[[Category: Aizawa, S]]		[[Category: Aizawa, S]]
	[[Category: Matsunami, H]]		[[Category: Matsunami, H]]

OCA at 10:23, 2 October 2019

OCA — Wed, 02 Oct 2019 10:23:31 GMT

←Older revision		Revision as of 10:23, 2 October 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6k3i is ~~ON HOLD until May 19 2021~~	+	==Salmonella hook in curved state - 66 subunit models==
-		+	<StructureSection load='6k3i' size='340' side='right'caption='[[6k3i]], [[Resolution\|resolution]] 2.86Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6k3i]] is a 66 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium_(strain_lt2_/_sgsc1412_/_atcc_700720) Salmonella typhimurium (strain lt2 / sgsc1412 / atcc 700720)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6K3I FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6k3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k3i OCA], [http://pdbe.org/6k3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k3i RCSB], [http://www.ebi.ac.uk/pdbsum/6k3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k3i ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Aizawa, S]]
		+	[[Category: Matsunami, H]]
		+	[[Category: Shibata, S]]
		+	[[Category: Wolf, M]]
		+	[[Category: Bacterial]]
		+	[[Category: Flagella]]
		+	[[Category: Flexible joint]]
		+	[[Category: Hook]]
		+	[[Category: Motor protein]]

OCA at 14:52, 14 August 2019

OCA — Wed, 14 Aug 2019 14:52:58 GMT

←Older revision		Revision as of 14:52, 14 August 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6k3i is ON HOLD	+	The entry 6k3i is ON HOLD until May 19 2021

	Authors:		Authors:

OCA: Protected "6k3i" [edit=sysop:move=sysop]

OCA — Wed, 29 May 2019 04:25:16 GMT

Protected "6k3i" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:25, 29 May 2019

OCA: New page: '''Unreleased structure''' The entry 6k3i is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 29 May 2019 04:25:14 GMT

New page: '''Unreleased structure''' The entry 6k3i is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6k3i is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]