6kbi - Revision history

OCA at 10:29, 22 November 2023

OCA — Wed, 22 Nov 2023 10:29:20 GMT

←Older revision		Revision as of 10:29, 22 November 2023
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	==Crystal structure of ErbB3 N418Q mutant==		==Crystal structure of ErbB3 N418Q mutant==
-	<StructureSection load='6kbi' size='340' side='right'caption='[[6kbi]]' scene=''>	+	<StructureSection load='6kbi' size='340' side='right'caption='[[6kbi]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KBI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6kbi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KBI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kbi OCA], [https://pdbe.org/6kbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kbi RCSB], [https://www.ebi.ac.uk/pdbsum/6kbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kbi ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kbi OCA], [https://pdbe.org/6kbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kbi RCSB], [https://www.ebi.ac.uk/pdbsum/6kbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kbi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/ERBB3_HUMAN ERBB3_HUMAN] Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2) [MIM:[https://omim.org/entry/607598 607598]; also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord. The LCCS2 syndrome is characterized by multiple joint contractures, anterior horn atrophy in the spinal cord, and a unique feature of a markedly distended urinary bladder. The phenotype suggests a spinal cord neuropathic etiology.<ref>PMID:17701904</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ERBB3_HUMAN ERBB3_HUMAN] Binds and is activated by neuregulins and NTAK.<ref>PMID:15358134</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Kato K]]		[[Category: Kato K]]
	[[Category: Yao M]]		[[Category: Yao M]]

OCA at 08:47, 18 February 2021

OCA — Thu, 18 Feb 2021 08:47:47 GMT

←Older revision		Revision as of 08:47, 18 February 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 6kbi ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of ErbB3 N418Q mutant==
-		+	<StructureSection load='6kbi' size='340' side='right'caption='[[6kbi]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KBI FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kbi OCA], [https://pdbe.org/6kbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kbi RCSB], [https://www.ebi.ac.uk/pdbsum/6kbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kbi ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Kato K]]
		+	[[Category: Yao M]]

OCA at 03:57, 10 July 2019

OCA — Wed, 10 Jul 2019 03:57:45 GMT

←Older revision		Revision as of 03:57, 10 July 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6kbi is ON HOLD	+	The entry 6kbi is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6kbi" [edit=sysop:move=sysop]

OCA — Wed, 03 Jul 2019 04:06:37 GMT

Protected "6kbi" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:06, 3 July 2019

OCA: New page: '''Unreleased structure''' The entry 6kbi is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 03 Jul 2019 04:06:35 GMT

New page: '''Unreleased structure''' The entry 6kbi is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6kbi is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]