6kh4 - Revision history

OCA at 10:33, 22 November 2023

OCA — Wed, 22 Nov 2023 10:33:20 GMT

←Older revision		Revision as of 10:33, 22 November 2023
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	<StructureSection load='6kh4' size='340' side='right'caption='[[6kh4]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='6kh4' size='340' side='right'caption='[[6kh4]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6kh4]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Kuruma_prawn Kuruma prawn~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KH4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6KH4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6kh4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Penaeus_japonicus Penaeus japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KH4 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=FE:FE+(III)+ION'>FE</scene~~>, ~~<scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.302Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[http:~~/~~/en.wikipedia.org/wiki/Ferroxidase Ferroxidase]~~, ~~with EC number [http~~:~~//www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6kh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kh4 OCA], [~~http~~://pdbe.org/6kh4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6kh4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6kh4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6kh4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kh4 OCA], [https://pdbe.org/6kh4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kh4 RCSB], [https://www.ebi.ac.uk/pdbsum/6kh4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kh4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/T2B7E1_PENJP T2B7E1_PENJP]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.[RuleBase:RU361145]	+	[https://www.uniprot.org/uniprot/T2B7E1_PENJP T2B7E1_PENJP] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.[RuleBase:RU361145]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6kh4" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6kh4" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ferritin 3D structures\|Ferritin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ferroxidase]]
-	[[Category: Kuruma prawn]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen, H]]	+	[[Category: Penaeus japonicus]]
-	[[Category: Gu, C]]	+	[[Category: Chen H]]
-	[[Category: Wang, H]]	+	[[Category: Gu C]]
-	[[Category: Wang, Y]]	+	[[Category: Wang H]]
-	[[Category: Zhang, T]]	+	[[Category: Wang Y]]
-	[[Category: Zhao, G]]	+	[[Category: Zhang T]]
-	~~[[Category: Metal binding protein~~]]	+	[[Category: Zhao G]]

OCA at 07:08, 4 March 2020

OCA — Wed, 04 Mar 2020 07:08:57 GMT

←Older revision		Revision as of 07:08, 4 March 2020
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	<StructureSection load='6kh4' size='340' side='right'caption='[[6kh4]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='6kh4' size='340' side='right'caption='[[6kh4]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6kh4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KH4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6kh4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Kuruma_prawn Kuruma prawn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KH4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
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	</StructureSection>		</StructureSection>
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
		+	[[Category: Kuruma prawn]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Chen, H]]		[[Category: Chen, H]]

OCA at 15:28, 29 January 2020

OCA — Wed, 29 Jan 2020 15:28:05 GMT

←Older revision		Revision as of 15:28, 29 January 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6kh4 is ~~ON HOLD until Paper~~ Publication	+	==Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes==
		+	<StructureSection load='6kh4' size='340' side='right'caption='[[6kh4]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6kh4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KH4 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kh4 OCA], [http://pdbe.org/6kh4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kh4 RCSB], [http://www.ebi.ac.uk/pdbsum/6kh4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kh4 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/T2B7E1_PENJP T2B7E1_PENJP]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.[RuleBase:RU361145]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Metal-organic frameworks (MOFs) hold great promise for numerous applications. However, proteins, carriers of biological functions in living systems, have not yet been fully explored as building blocks for the construction of MOFs. Here, we presented a strategy for the fabrication of binary MOFs. Considering octahedral ferritin symmetry, we firstly incorporated four His 2 (His-His) motifs into the exterior surface of ferritin nanocage nearby each C 4 channel, yielding protein linkers with multiple metal binding sites (bisH-SF). Secondly, by adding nickel ions to bisH-SF solutions to triggers the self-assembly of ferritin nanocages into a porous 3D crystalline MOF with designed protein lattice, where two adjacent ferritin molecules along the C 4 symmetry axes are bridged by four dinuclear or tetranuclear nickel clusters depending on Ni 2+ concentration. This work provides a simple approach for precise control over a binary protein-metal crystalline framework, and resulting MOFs exhibited inherent ferroxidase activity and peroxidase-like catalytic activity.

-	~~Authors~~:	+	Structural Insight into Binary Protein MOFs with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.,Gu C, Chen H, Wang Y, Zhang T, Wang H, Zhao G Chemistry. 2019 Dec 9. doi: 10.1002/chem.201905315. PMID:31820500<ref>PMID:31820500</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6kh4" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Ferroxidase]]
		+	[[Category: Large Structures]]
		+	[[Category: Chen, H]]
		+	[[Category: Gu, C]]
		+	[[Category: Wang, H]]
		+	[[Category: Wang, Y]]
		+	[[Category: Zhang, T]]
		+	[[Category: Zhao, G]]
		+	[[Category: Metal binding protein]]

OCA at 03:31, 10 October 2019

OCA — Thu, 10 Oct 2019 03:31:22 GMT

←Older revision		Revision as of 03:31, 10 October 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6kh4 is ON HOLD	+	The entry 6kh4 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6kh4" [edit=sysop:move=sysop]

OCA — Wed, 17 Jul 2019 08:50:23 GMT

Protected "6kh4" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:50, 17 July 2019

OCA: New page: '''Unreleased structure''' The entry 6kh4 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 17 Jul 2019 08:50:21 GMT

New page: '''Unreleased structure''' The entry 6kh4 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6kh4 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]