6kyx - Revision history

OCA at 10:44, 27 March 2024

OCA — Wed, 27 Mar 2024 10:44:50 GMT

←Older revision		Revision as of 10:44, 27 March 2024
Line 1:		Line 1:

	==Crystal Structure of Staphylococcus aureus response regulator ArlR DNA binding domain with His tag cleaved==		==Crystal Structure of Staphylococcus aureus response regulator ArlR DNA binding domain with His tag cleaved==
-	<StructureSection load='6kyx' size='340' side='right'caption='[[6kyx]]' scene=''>	+	<StructureSection load='6kyx' size='340' side='right'caption='[[6kyx]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KYX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6KYX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6kyx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KYX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6kyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kyx OCA], [~~http~~://pdbe.org/6kyx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6kyx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6kyx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6kyx ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.0048Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kyx OCA], [https://pdbe.org/6kyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kyx RCSB], [https://www.ebi.ac.uk/pdbsum/6kyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kyx ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ARLR_STAA8 ARLR_STAA8] Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence. ArlS/ArlR affects expression of the multidrug resistance transporter NorA and interacts with both Agr (virulence accessory gene regulator) (negatively) and SarA (staphylococcal accessory regulator) (positively) to modulate several virulence factor genes, including ssp (serine protease), spa (surface protein A) and hla (alpha-hemolysin). Could inhibit biofilm development by a mechanism independent of the presence of the poly-N-acetylglucosamine (PNAG). Also, Arl proteins are required for the efficient activity of DNA gyrase inhibitors and high osmolarity on spa expression.<ref>PMID:10633099</ref> <ref>PMID:10869073</ref> <ref>PMID:11454217</ref> <ref>PMID:15528666</ref> <ref>PMID:16030226</ref>
		+
		+	==See Also==
		+	*[[Response regulator 3D structure\|Response regulator 3D structure]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Staphylococcus aureus]]
	[[Category: Ouyang Z]]		[[Category: Ouyang Z]]
	[[Category: Wen Y]]		[[Category: Wen Y]]

OCA at 11:08, 23 September 2020

OCA — Wed, 23 Sep 2020 11:08:00 GMT

←Older revision		Revision as of 11:08, 23 September 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6kyx is ON HOLD until Paper Publication~~	+	==Crystal Structure of Staphylococcus aureus response regulator ArlR DNA binding domain with His tag cleaved==
-		+	<StructureSection load='6kyx' size='340' side='right'caption='[[6kyx]]' scene=''>
-	~~Authors: Wen, Y., Ouyang, Z.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KYX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6KYX FirstGlance]. <br>
-	~~Description:~~ Crystal Structure of Staphylococcus aureus response regulator ArlR DNA binding domain with His tag cleaved	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6kyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kyx OCA], [http://pdbe.org/6kyx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kyx RCSB], [http://www.ebi.ac.uk/pdbsum/6kyx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kyx ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Wen~~, Y]]	+	__TOC__
-	[[Category: Ouyang, Z]]	+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Ouyang Z]]
		+	[[Category: Wen Y]]

OCA at 05:35, 18 December 2019

OCA — Wed, 18 Dec 2019 05:35:05 GMT

←Older revision		Revision as of 05:35, 18 December 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6kyx is ON HOLD	+	The entry 6kyx is ON HOLD until Paper Publication

	Authors: Wen, Y., Ouyang, Z.		Authors: Wen, Y., Ouyang, Z.

OCA: Protected "6kyx" [edit=sysop:move=sysop]

OCA — Wed, 02 Oct 2019 07:01:01 GMT

Protected "6kyx" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:01, 2 October 2019

OCA: New page: '''Unreleased structure''' The entry 6kyx is ON HOLD Authors: Wen, Y., Ouyang, Z. Description: Crystal Structure of Staphylococcus aureus response regulator ArlR DNA binding domain wit...

OCA — Wed, 02 Oct 2019 07:00:59 GMT

New page: '''Unreleased structure''' The entry 6kyx is ON HOLD Authors: Wen, Y., Ouyang, Z. Description: Crystal Structure of Staphylococcus aureus response regulator ArlR DNA binding domain wit...

New page

'''Unreleased structure'''

The entry 6kyx is ON HOLD

Authors: Wen, Y., Ouyang, Z.

Description: Crystal Structure of Staphylococcus aureus response regulator ArlR DNA binding domain with His tag cleaved
[[Category: Unreleased Structures]]
[[Category: Wen, Y]]
[[Category: Ouyang, Z]]