6l9z - Revision history

OCA at 10:53, 22 November 2023

OCA — Wed, 22 Nov 2023 10:53:56 GMT

←Older revision		Revision as of 10:53, 22 November 2023
Line 1:		Line 1:

-	====	+	==338 bp di-nucleosome assembled with linker histone H1.X==
-	<StructureSection load='6l9z' size='340' side='right'caption='[[6l9z]]' scene=''>	+	<StructureSection load='6l9z' size='340' side='right'caption='[[6l9z]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6l9z]] is a 19 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Other_sequences Other sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L9Z FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l9z OCA], [https://pdbe.org/6l9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l9z RCSB], [https://www.ebi.ac.uk/pdbsum/6l9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l9z ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l9z OCA], [https://pdbe.org/6l9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l9z RCSB], [https://www.ebi.ac.uk/pdbsum/6l9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l9z ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/H31_HUMAN H31_HUMAN]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Structural characterization of chromatin is challenging due to conformational and compositional heterogeneity in vivo and dynamic properties that limit achievable resolution in vitro. Although the maximum resolution for solving structures of large macromolecular assemblies by electron microscopy has recently undergone profound increases, X-ray crystallographic approaches may still offer advantages for certain systems. One such system is compact chromatin, wherein the crystalline state recapitulates the crowded molecular environment within the nucleus. Here we show that nucleosomal constructs with cohesive-ended DNA can be designed that assemble into different types of circular configurations or continuous fibers extending throughout crystals. We demonstrate the utility of the method for characterizing nucleosome compaction and linker histone binding at near-atomic resolution but also advance its application for tackling further problems in chromatin structural biology and for generating novel types of DNA nanostructures. We provide a library of cohesive-ended DNA fragment expression constructs and a strategy for engineering DNA-based nanomaterials with a seemingly vast potential variety of architectures and histone chemistries.
		+
		+	Engineering nucleosomes for generating diverse chromatin assemblies.,Adhireksan Z, Sharma D, Lee PL, Bao Q, Padavattan S, Shum WK, Davey GE, Davey CA Nucleic Acids Res. 2021 May 21;49(9):e52. doi: 10.1093/nar/gkab070. PMID:33590100<ref>PMID:33590100</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6l9z" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Histone 3D structures\|Histone 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Z~~-disk~~]]	+	[[Category: Other sequences]]
		+	[[Category: Adhireksan Z]]
		+	[[Category: Davey CA]]
		+	[[Category: Lee PL]]
		+	[[Category: Sharma D]]

OCA at 09:55, 17 February 2021

OCA — Wed, 17 Feb 2021 09:55:19 GMT

←Older revision		Revision as of 09:55, 17 February 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6l9z ~~is ON HOLD until Feb 11 2022~~	+	====
-		+	<StructureSection load='6l9z' size='340' side='right'caption='[[6l9z]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l9z OCA], [https://pdbe.org/6l9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l9z RCSB], [https://www.ebi.ac.uk/pdbsum/6l9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l9z ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 04:18, 7 October 2020

OCA — Wed, 07 Oct 2020 04:18:22 GMT

←Older revision		Revision as of 04:18, 7 October 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6l9z is ON HOLD until ~~Paper Publication~~	+	The entry 6l9z is ON HOLD until Feb 11 2022

	Authors:		Authors:

OCA at 13:22, 11 December 2019

OCA — Wed, 11 Dec 2019 13:22:54 GMT

←Older revision		Revision as of 13:22, 11 December 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6l9z is ON HOLD	+	The entry 6l9z is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6l9z" [edit=sysop:move=sysop]

OCA — Wed, 20 Nov 2019 13:27:12 GMT

Protected "6l9z" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:27, 20 November 2019

OCA: New page: '''Unreleased structure''' The entry 6l9z is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 20 Nov 2019 13:27:10 GMT

New page: '''Unreleased structure''' The entry 6l9z is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6l9z is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]