6lf7 - Revision history

OCA at 10:59, 22 November 2023

OCA — Wed, 22 Nov 2023 10:59:05 GMT

←Older revision		Revision as of 10:59, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution\|resolution]] 1.79Å' scene=''>		<StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution\|resolution]] 1.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4n7a 4n7a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LF7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6LF7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4n7a 4n7a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LF7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LF7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.794Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxidase Peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.7 1.11.1.7] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6lf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lf7 OCA], [~~http~~://pdbe.org/6lf7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6lf7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6lf7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6lf7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lf7 OCA], [https://pdbe.org/6lf7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lf7 RCSB], [https://www.ebi.ac.uk/pdbsum/6lf7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lf7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI]] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref>	+	[https://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref>
		+
		+	==See Also==
		+	*[[Lactoperoxidase\|Lactoperoxidase]]
	== References ==		== References ==
	<references/>		<references/>
Line 16:		Line 19:
	[[Category: Capra hircus]]		[[Category: Capra hircus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Peroxidase]]~~	+	[[Category: Bhushan A]]
-	[[Category: Bhushan, A]]	+	[[Category: Kaur P]]
-	[[Category: Kaur, P]]	+	[[Category: Sharma S]]
-	[[Category: Sharma, S]]	+	[[Category: Singh A]]
-	[[Category: Singh, A]]	+	[[Category: Singh AK]]
-	[[Category: Singh~~, A K~~]]	+	[[Category: Singh RP]]
-	[[Category: Singh~~, R P~~]]	+	[[Category: Singh TP]]
-	[[Category: Singh~~, T P~~]]	+	[[Category: Sinha M]]
-	[[Category: Sinha, M]]	+	[[Category: Tyagi TK]]
-	[[Category: Tyagi~~, T K~~]]	+	[[Category: Viswanathan V]]
-	[[Category: Viswanathan, V]]	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Peroxide family~~]]	+

OCA at 16:04, 22 January 2020

OCA — Wed, 22 Jan 2020 16:04:51 GMT

←Older revision		Revision as of 16:04, 22 January 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6lf7 ~~is ON HOLD~~	+	==Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.==
-		+	<StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution\|resolution]] 1.79Å' scene=''>
-	~~Authors~~: ~~Viswanathan, V~~.~~, Tyagi, T~~.K.~~, Singh, R~~.P.~~, Singh, A~~.K., ~~Singh~~, A., ~~Bhushan~~, A., ~~Sinha~~, M., ~~Kaur~~, P., ~~Sharma~~, S., ~~Singh~~, T.P.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4n7a 4n7a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LF7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LF7 FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and~~ hydrogen peroxide ~~at 1~~.79 A ~~resolution~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxidase Peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.7 1.11.1.7] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6lf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lf7 OCA], [http://pdbe.org/6lf7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lf7 RCSB], [http://www.ebi.ac.uk/pdbsum/6lf7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lf7 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI]] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Capra hircus]]
		+	[[Category: Large Structures]]
		+	[[Category: Peroxidase]]
	[[Category: Bhushan, A]]		[[Category: Bhushan, A]]
-	[[Category: ~~Tyagi~~, T.K]]	+	[[Category: Kaur, P]]
		+	[[Category: Sharma, S]]
		+	[[Category: Singh, A]]
		+	[[Category: Singh, A K]]
		+	[[Category: Singh, R P]]
		+	[[Category: Singh, T P]]
	[[Category: Sinha, M]]		[[Category: Sinha, M]]
		+	[[Category: Tyagi, T K]]
	[[Category: Viswanathan, V]]		[[Category: Viswanathan, V]]
-	[[Category: ~~Sharma, S~~]]	+	[[Category: Oxidoreductase]]
-	[[Category: ~~Singh, R.P]]~~	+	[[Category: Peroxide family]]
-	~~[[Category: Singh, T.P]]~~	+
-	~~[[Category: Singh, A.K]]~~	+
-	~~[[Category: Singh, A]]~~	+
-	~~[[Category: Kaur, P~~]]	+

OCA: Protected "6lf7" [edit=sysop:move=sysop]

OCA — Wed, 11 Dec 2019 13:25:11 GMT

Protected "6lf7" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:25, 11 December 2019

OCA: New page: '''Unreleased structure''' The entry 6lf7 is ON HOLD Authors: Viswanathan, V., Tyagi, T.K., Singh, R.P., Singh, A.K., Singh, A., Bhushan, A., Sinha, M., Kaur, P., Sharma, S., Singh, T.P...

OCA — Wed, 11 Dec 2019 13:25:09 GMT

New page: '''Unreleased structure''' The entry 6lf7 is ON HOLD Authors: Viswanathan, V., Tyagi, T.K., Singh, R.P., Singh, A.K., Singh, A., Bhushan, A., Sinha, M., Kaur, P., Sharma, S., Singh, T.P...

New page

'''Unreleased structure'''

The entry 6lf7 is ON HOLD

Authors: Viswanathan, V., Tyagi, T.K., Singh, R.P., Singh, A.K., Singh, A., Bhushan, A., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.

Description: Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.
[[Category: Unreleased Structures]]
[[Category: Bhushan, A]]
[[Category: Tyagi, T.K]]
[[Category: Sinha, M]]
[[Category: Viswanathan, V]]
[[Category: Sharma, S]]
[[Category: Singh, R.P]]
[[Category: Singh, T.P]]
[[Category: Singh, A.K]]
[[Category: Singh, A]]
[[Category: Kaur, P]]