6lvo - Revision history

OCA at 14:56, 29 November 2023

OCA — Wed, 29 Nov 2023 14:56:46 GMT

←Older revision		Revision as of 14:56, 29 November 2023
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	<StructureSection load='6lvo' size='340' side='right'caption='[[6lvo]], [[Resolution\|resolution]] 2.36Å' scene=''>		<StructureSection load='6lvo' size='340' side='right'caption='[[6lvo]], [[Resolution\|resolution]] 2.36Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6lvo]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bosea_sp.~~_pamc_26642~~ Bosea sp. ~~pamc~~ 26642]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6LVO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6lvo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bosea_sp._PAMC_26642 Bosea sp. PAMC 26642]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LVO FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~AXW83_14375 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=1792307 Bosea sp. PAMC 26642])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.36Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6lvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvo OCA], [~~http~~://pdbe.org/6lvo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6lvo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6lvo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvo ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvo OCA], [https://pdbe.org/6lvo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lvo RCSB], [https://www.ebi.ac.uk/pdbsum/6lvo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvo ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A126P0C4_9HYPH A0A126P0C4_9HYPH]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bosea sp. ~~pamc~~ 26642]]	+	[[Category: Bosea sp. PAMC 26642]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hwang, J]]	+	[[Category: Hwang J]]
-	[[Category: Jung, C]]	+	[[Category: Jung C]]
-	[[Category: Lee~~, C W~~]]	+	[[Category: Lee CW]]
-	[[Category: Lee~~, J H]]~~	+	[[Category: Lee JH]]
-	~~[[Category: Enoyl-coa]]~~	+
-	~~[[Category: Isomerase~~]]	+

OCA at 08:06, 11 November 2020

OCA — Wed, 11 Nov 2020 08:06:09 GMT

←Older revision		Revision as of 08:06, 11 November 2020
Line 1:		Line 1:

	==Enoyl-CoA isomerase (BoECI) from Bosea sp. PAMC 26642==		==Enoyl-CoA isomerase (BoECI) from Bosea sp. PAMC 26642==
-	<StructureSection load='6lvo' size='340' side='right'caption='[[6lvo]]' scene=''>	+	<StructureSection load='6lvo' size='340' side='right'caption='[[6lvo]], [[Resolution\|resolution]] 2.36Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6LVO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6lvo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bosea_sp._pamc_26642 Bosea sp. pamc 26642]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6LVO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6lvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvo OCA], [http://pdbe.org/6lvo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lvo RCSB], [http://www.ebi.ac.uk/pdbsum/6lvo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvo ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AXW83_14375 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1792307 Bosea sp. PAMC 26642])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6lvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvo OCA], [http://pdbe.org/6lvo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lvo RCSB], [http://www.ebi.ac.uk/pdbsum/6lvo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvo ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Crystal structures of enoyl-coenzyme A (CoA) isomerase from Bosea sp. PAMC 26642 (BoECI) and enoyl-CoA hydratase from Hymenobacter sp. PAMC 26628 (HyECH) were determined at 2.35 and 2.70 A resolution, respectively. BoECI and HyECH are members of the crotonase superfamily and are enzymes known to be involved in fatty acid degradation. Structurally, these enzymes are highly similar except for the orientation of their C-terminal helix domain. Analytical ultracentrifugation was performed to determine the oligomerization states of BoECI and HyECH revealing they exist as trimers in solution. However, their putative ligand-binding sites and active site residue compositions are dissimilar. Comparative sequence and structural analysis revealed that the active site of BoECI had one glutamate residue (Glu135), this site is occupied by an aspartate in some ECIs, and the active sites of HyECH had two highly conserved glutamate residues (Glu118 and Glu138). Moreover, HyECH possesses a salt bridge interaction between Glu98 and Arg152 near the active site. This interaction may allow the catalytic Glu118 residue to have a specific conformation for the ECH enzyme reaction. This salt bridge interaction is highly conserved in known bacterial ECH structures and ECI enzymes do not have this type of interaction. Collectively, our comparative sequential and structural studies have provided useful information to distinguish and classify two similar bacterial crotonase superfamily enzymes.
		+
		+	Structural and sequence comparisons of bacterial enoyl-CoA isomerase and enoyl-CoA hydratase.,Hwang J, Jeong CS, Lee CW, Shin SC, Kim HW, Lee SG, Youn UJ, Lee CS, Oh TJ, Kim HJ, Park H, Park HH, Lee JH J Microbiol. 2020 Jul;58(7):606-613. doi: 10.1007/s12275-020-0089-1. Epub 2020, Apr 22. PMID:32323197<ref>PMID:32323197</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6lvo" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Enoyl-CoA hydratase 3D structures\|Enoyl-CoA hydratase 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bosea sp. pamc 26642]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hwang J]]	+	[[Category: Hwang, J]]
-	[[Category: Jung C]]	+	[[Category: Jung, C]]
-	[[Category: Lee CW]]	+	[[Category: Lee, C W]]
-	[[Category: Lee JH]]	+	[[Category: Lee, J H]]
		+	[[Category: Enoyl-coa]]
		+	[[Category: Isomerase]]

OCA at 06:41, 29 April 2020

OCA — Wed, 29 Apr 2020 06:41:08 GMT

←Older revision		Revision as of 06:41, 29 April 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6lvo ~~is ON HOLD~~	+	==Enoyl-CoA isomerase (BoECI) from Bosea sp. PAMC 26642==
-		+	<StructureSection load='6lvo' size='340' side='right'caption='[[6lvo]]' scene=''>
-	~~Authors~~: ~~Hwang, J~~., ~~Jung~~, C., ~~Lee, C~~.W., ~~Lee, J~~.H.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6LVO FirstGlance]. <br>
-	~~Description~~: ~~Enoyl~~-~~CoA isomerase (BoECI) from Bosea sp~~. ~~PAMC 26642~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6lvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvo OCA], [http://pdbe.org/6lvo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lvo RCSB], [http://www.ebi.ac.uk/pdbsum/6lvo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvo ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Jung, C~~]]	+	__TOC__
-	[[Category: ~~Lee, J.H~~]]	+	</StructureSection>
-	[[Category: ~~Hwang, J~~]]	+	[[Category: Large Structures]]
-	[[Category: Lee~~, C.W~~]]	+	[[Category: Hwang J]]
		+	[[Category: Jung C]]
		+	[[Category: Lee CW]]
		+	[[Category: Lee JH]]

OCA: Protected "6lvo" [edit=sysop:move=sysop]

OCA — Thu, 13 Feb 2020 02:34:03 GMT

Protected "6lvo" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:34, 13 February 2020

OCA: New page: '''Unreleased structure''' The entry 6lvo is ON HOLD Authors: Hwang, J., Jung, C., Lee, C.W., Lee, J.H. Description: Enoyl-CoA isomerase (BoECI) from Bosea sp. PAMC 26642 [[Category: U...

OCA — Thu, 13 Feb 2020 02:34:01 GMT

New page: '''Unreleased structure''' The entry 6lvo is ON HOLD Authors: Hwang, J., Jung, C., Lee, C.W., Lee, J.H. Description: Enoyl-CoA isomerase (BoECI) from Bosea sp. PAMC 26642 [[Category: U...

New page

'''Unreleased structure'''

The entry 6lvo is ON HOLD

Authors: Hwang, J., Jung, C., Lee, C.W., Lee, J.H.

Description: Enoyl-CoA isomerase (BoECI) from Bosea sp. PAMC 26642
[[Category: Unreleased Structures]]
[[Category: Jung, C]]
[[Category: Lee, J.H]]
[[Category: Hwang, J]]
[[Category: Lee, C.W]]