6n90 - Revision history

OCA at 06:47, 11 October 2023

OCA — Wed, 11 Oct 2023 06:47:43 GMT

←Older revision		Revision as of 06:47, 11 October 2023
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	<StructureSection load='6n90' size='340' side='right'caption='[[6n90]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='6n90' size='340' side='right'caption='[[6n90]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6n90]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"achromobacter_radiobacter"_(beijerinck_and_van_delden_1902)_bergey_et_al._1934 "achromobacter radiobacter" (beijerinck and van delden 1902) bergey et al. 1934~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N90 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6N90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6n90]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6N90 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=TEW:6~~-~~TUNGSTOTELLURATE(VI)'>TEW</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.755Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>Atu2017 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~358~~ "~~Achromobacter radiobacter~~" (~~Beijerinck and van Delden 1902) Bergey et al. 1934]~~)</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TEW:6-TUNGSTOTELLURATE(VI)'>TEW</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6n90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n90 OCA], [~~http~~://pdbe.org/6n90 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6n90 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6n90 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6n90 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6n90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n90 OCA], [https://pdbe.org/6n90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n90 RCSB], [https://www.ebi.ac.uk/pdbsum/6n90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n90 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A9CID9_AGRFC A9CID9_AGRFC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Agrobacterium tumefaciens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bourne~~, C R~~]]	+	[[Category: Bourne CR]]
-	[[Category: Reddem~~, E R]]~~	+	[[Category: Reddem ER]]
-	~~[[Category: Toxin~~]]	+

OCA at 11:20, 22 July 2020

OCA — Wed, 22 Jul 2020 11:20:49 GMT

←Older revision		Revision as of 11:20, 22 July 2020
Line 3:		Line 3:
	<StructureSection load='6n90' size='340' side='right'caption='[[6n90]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='6n90' size='340' side='right'caption='[[6n90]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6n90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_radiobacter"_(beijerinck_and_van_delden_1902)_bergey_et_al._1934 "achromobacter radiobacter" (beijerinck and van delden 1902) bergey et al. 1934]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N90 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6N90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6n90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_radiobacter"_(beijerinck_and_van_delden_1902)_bergey_et_al._1934 "achromobacter radiobacter" (beijerinck and van delden 1902) bergey et al. 1934]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N90 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6N90 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TEW:6-TUNGSTOTELLURATE(VI)'>TEW</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TEW:6-TUNGSTOTELLURATE(VI)'>TEW</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Atu2017 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=358 "Achromobacter radiobacter" (Beijerinck and van Delden 1902) Bergey et al. 1934])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Atu2017 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=358 "Achromobacter radiobacter" (Beijerinck and van Delden 1902) Bergey et al. 1934])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6n90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n90 OCA], [http://pdbe.org/6n90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n90 RCSB], [http://www.ebi.ac.uk/pdbsum/6n90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n90 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6n90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n90 OCA], [http://pdbe.org/6n90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n90 RCSB], [http://www.ebi.ac.uk/pdbsum/6n90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n90 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The ribosome-dependent E. coli (Ec) mRNase toxin YoeB has been demonstrated to protect cells during thermal stress. Agrobacterium tumefaciens (At), a plant pathogen, also encodes a YoeB toxin. Initial studies indicated that AtYoeB does not impact the growth of Ec, but its expression is toxic to the native host At. The current work examines this species-specific effect. We establish the highly similar structure and function of Ec and AtYoeB toxins, including the ability of the AtYoeB toxin to inhibit Ec ribosomes in vitro. Comparison of YoeB sequences and structures highlights a four-residue helix between beta-strands 2 and 3 that interacts with mRNA bases within the ribosome. This helix sequence is varied among YoeB toxins, and this variation correlates with bacterial classes of proteobacteria. When the four amino acid sequence of this helix is transplanted from EcYoeB onto AtYoeB, the resulting chimera gains toxicity to Ec cells and lessens toxicity to At cells. The reverse is also true, such that EcYoeB with the AtYoeB helix sequence is less toxic to Ec and gains toxicity to At cultures. We suggest this helix sequence directs mRNA sequence-specific degradation, which varies among proteobacterial classes, and thus controls growth inhibition and YoeB toxicity.
		+
		+	Identifying a Molecular Mechanism That Imparts Species-Specific Toxicity to YoeB Toxins.,Ames JR, McGillick J, Murphy T, Reddem E, Bourne CR Front Microbiol. 2020 May 21;11:959. doi: 10.3389/fmicb.2020.00959. eCollection, 2020. PMID:32528435<ref>PMID:32528435</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6n90" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:37, 1 January 2020

OCA — Wed, 01 Jan 2020 11:37:53 GMT

←Older revision		Revision as of 11:37, 1 January 2020
Line 3:		Line 3:
	<StructureSection load='6n90' size='340' side='right'caption='[[6n90]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='6n90' size='340' side='right'caption='[[6n90]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6n90]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6n90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_radiobacter"_(beijerinck_and_van_delden_1902)_bergey_et_al._1934 "achromobacter radiobacter" (beijerinck and van delden 1902) bergey et al. 1934]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N90 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TEW:6-TUNGSTOTELLURATE(VI)'>TEW</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TEW:6-TUNGSTOTELLURATE(VI)'>TEW</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Atu2017 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=358 "Achromobacter radiobacter" (Beijerinck and van Delden 1902) Bergey et al. 1934])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n90 OCA], [http://pdbe.org/6n90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n90 RCSB], [http://www.ebi.ac.uk/pdbsum/6n90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n90 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n90 OCA], [http://pdbe.org/6n90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n90 RCSB], [http://www.ebi.ac.uk/pdbsum/6n90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n90 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:43, 6 November 2019

OCA — Wed, 06 Nov 2019 06:43:28 GMT

←Older revision		Revision as of 06:43, 6 November 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6n90 is ~~ON HOLD until Paper Publication~~	+	==YoeB/ParE toxin from Agrobacterium tumefaciens==
-		+	<StructureSection load='6n90' size='340' side='right'caption='[[6n90]], [[Resolution\|resolution]] 1.75Å' scene=''>
-	~~Authors~~: ~~Bourne~~, C.R., ~~Reddem~~, E.R.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6n90]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N90 FirstGlance]. <br>
-	~~Description: YoeB~~/~~ParE toxin from Agrobacterium tumefaciens~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TEW:6-TUNGSTOTELLURATE(VI)'>TEW</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n90 OCA], [http://pdbe.org/6n90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n90 RCSB], [http://www.ebi.ac.uk/pdbsum/6n90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n90 ProSAT]</span></td></tr>
-	[[Category: ~~Reddem~~, E.R]]	+	</table>
-	[[Category: ~~Bourne~~, C.R]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Bourne, C R]]
		+	[[Category: Reddem, E R]]
		+	[[Category: Toxin]]

OCA at 06:45, 26 December 2018

OCA — Wed, 26 Dec 2018 06:45:31 GMT

←Older revision		Revision as of 06:45, 26 December 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6n90 is ON HOLD	+	The entry 6n90 is ON HOLD until Paper Publication

	Authors: Bourne, C.R., Reddem, E.R.		Authors: Bourne, C.R., Reddem, E.R.

OCA: Protected "6n90" [edit=sysop:move=sysop]

OCA — Wed, 12 Dec 2018 05:21:48 GMT

Protected "6n90" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:21, 12 December 2018

OCA: New page: '''Unreleased structure''' The entry 6n90 is ON HOLD Authors: Bourne, C.R., Reddem, E.R. Description: YoeB/ParE toxin from Agrobacterium tumefaciens Category: Unreleased Structures...

OCA — Wed, 12 Dec 2018 05:21:47 GMT

New page: '''Unreleased structure''' The entry 6n90 is ON HOLD Authors: Bourne, C.R., Reddem, E.R. Description: YoeB/ParE toxin from Agrobacterium tumefaciens Category: Unreleased Structures...

New page

'''Unreleased structure'''

The entry 6n90 is ON HOLD

Authors: Bourne, C.R., Reddem, E.R.

Description: YoeB/ParE toxin from Agrobacterium tumefaciens
[[Category: Unreleased Structures]]
[[Category: Reddem, E.R]]
[[Category: Bourne, C.R]]