6nfa - Revision history

OCA at 06:52, 11 October 2023

OCA — Wed, 11 Oct 2023 06:52:31 GMT

←Older revision		Revision as of 06:52, 11 October 2023
Line 3:		Line 3:
	<StructureSection load='6nfa' size='340' side='right'caption='[[6nfa]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='6nfa' size='340' side='right'caption='[[6nfa]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nfa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NFA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6NFA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nfa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NFA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9K1:(2S)-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}-3-(pyridin-3-yl)propan-1-ol'>9K1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6new\|6new]], [[6nf1\|6nf1]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9K1:(2S)-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}-3-(pyridin-3-yl)propan-1-ol'>9K1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6nfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nfa OCA], [~~http~~://pdbe.org/6nfa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6nfa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6nfa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6nfa ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nfa OCA], [https://pdbe.org/6nfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nfa RCSB], [https://www.ebi.ac.uk/pdbsum/6nfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nfa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/VAV_HUMAN VAV_HUMAN]] Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.	+	[https://www.uniprot.org/uniprot/VAV_HUMAN VAV_HUMAN] Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Elling~~, R A~~]]	+	[[Category: Elling RA]]
-	[[Category: Knapp~~, M S~~]]	+	[[Category: Knapp MS]]
-	[[Category: Ornelas, E]]	+	[[Category: Ornelas E]]
-	~~[[Category: Gef]]~~	+
-	~~[[Category: Rac]]~~	+
-	~~[[Category: Signaling protein-inhibitor complex]]~~	+
-	~~[[Category: Vav1~~]]	+

OCA at 09:07, 25 December 2019

OCA — Wed, 25 Dec 2019 09:07:39 GMT

←Older revision		Revision as of 09:07, 25 December 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6nfa is ~~ON HOLD until Paper Publication~~	+	==Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity==
-		+	<StructureSection load='6nfa' size='340' side='right'caption='[[6nfa]], [[Resolution\|resolution]] 2.70Å' scene=''>
-	~~Authors~~: ~~Knapp~~, M.S., ~~Elling~~, R.A., ~~Ornelas~~, E.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6nfa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NFA FirstGlance]. <br>
-	~~Description~~: ~~Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9K1:(2S)-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}-3-(pyridin-3-yl)propan-1-ol'>9K1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6new\|6new]], [[6nf1\|6nf1]]</td></tr>
-	[[Category: Elling, R.A]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nfa OCA], [http://pdbe.org/6nfa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nfa RCSB], [http://www.ebi.ac.uk/pdbsum/6nfa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nfa ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/VAV_HUMAN VAV_HUMAN]] Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Elling, R A]]
		+	[[Category: Knapp, M S]]
	[[Category: Ornelas, E]]		[[Category: Ornelas, E]]
-	[[Category: ~~Knapp, M.S~~]]	+	[[Category: Gef]]
		+	[[Category: Rac]]
		+	[[Category: Signaling protein-inhibitor complex]]
		+	[[Category: Vav1]]

OCA at 07:43, 10 May 2019

OCA — Fri, 10 May 2019 07:43:38 GMT

←Older revision		Revision as of 07:43, 10 May 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6nfa is ON HOLD	+	The entry 6nfa is ON HOLD until Paper Publication

	Authors: Knapp, M.S., Elling, R.A., Ornelas, E.		Authors: Knapp, M.S., Elling, R.A., Ornelas, E.

OCA at 04:51, 24 April 2019

OCA — Wed, 24 Apr 2019 04:51:21 GMT

←Older revision		Revision as of 04:51, 24 April 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6nfa is ON HOLD ~~until Paper Publication~~	+	The entry 6nfa is ON HOLD

	Authors: Knapp, M.S., Elling, R.A., Ornelas, E.		Authors: Knapp, M.S., Elling, R.A., Ornelas, E.
Line 7:		Line 7:
	Description: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity		Description: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Knapp, M.S]]
	[[Category: Elling, R.A]]		[[Category: Elling, R.A]]
	[[Category: Ornelas, E]]		[[Category: Ornelas, E]]
		+	[[Category: Knapp, M.S]]

OCA at 07:33, 13 February 2019

OCA — Wed, 13 Feb 2019 07:33:06 GMT

←Older revision		Revision as of 07:33, 13 February 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6nfa is ON HOLD	+	The entry 6nfa is ON HOLD until Paper Publication

	Authors: Knapp, M.S., Elling, R.A., Ornelas, E.		Authors: Knapp, M.S., Elling, R.A., Ornelas, E.
Line 7:		Line 7:
	Description: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity		Description: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Knapp, M.S]]
	[[Category: Elling, R.A]]		[[Category: Elling, R.A]]
	[[Category: Ornelas, E]]		[[Category: Ornelas, E]]
-	[[Category: Knapp, M.S]]

OCA: Protected "6nfa" [edit=sysop:move=sysop]

OCA — Wed, 26 Dec 2018 06:51:24 GMT

Protected "6nfa" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:51, 26 December 2018

OCA: New page: '''Unreleased structure''' The entry 6nfa is ON HOLD Authors: Knapp, M.S., Elling, R.A., Ornelas, E. Description: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF a...

OCA — Wed, 26 Dec 2018 06:51:23 GMT

New page: '''Unreleased structure''' The entry 6nfa is ON HOLD Authors: Knapp, M.S., Elling, R.A., Ornelas, E. Description: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF a...

New page

'''Unreleased structure'''

The entry 6nfa is ON HOLD

Authors: Knapp, M.S., Elling, R.A., Ornelas, E.

Description: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity
[[Category: Unreleased Structures]]
[[Category: Elling, R.A]]
[[Category: Ornelas, E]]
[[Category: Knapp, M.S]]