6nmy - Revision history

OCA at 06:56, 11 October 2023

OCA — Wed, 11 Oct 2023 06:56:24 GMT

←Older revision		Revision as of 06:56, 11 October 2023
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	<StructureSection load='6nmy' size='340' side='right'caption='[[6nmy]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='6nmy' size='340' side='right'caption='[[6nmy]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nmy]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NMY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6NMY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nmy]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NMY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NMY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.301Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6nmy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nmy OCA], [~~http~~://pdbe.org/6nmy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6nmy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6nmy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6nmy ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nmy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nmy OCA], [https://pdbe.org/6nmy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nmy RCSB], [https://www.ebi.ac.uk/pdbsum/6nmy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nmy ProSAT]</span></td></tr>
	</table>		</table>
-	== Disease ==
-	[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] Defects in CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5) [MIM:[http://omim.org/entry/614370 614370]]. SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.<ref>PMID:21075760</ref>
	== Function ==		== Function ==
-	[~~[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. [[http~~://www.uniprot.org/uniprot/IL3RA_HUMAN IL3RA_HUMAN]] This is a receptor for interleukin-3. [[http://www.uniprot.org/uniprot/IL3_HUMAN IL3_HUMAN]] Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.	+	[https://www.uniprot.org/uniprot/IL3RA_HUMAN IL3RA_HUMAN] This is a receptor for interleukin-3.
-	== ~~References~~ ==	+
-	~~<references/>~~	+	==See Also==
		+	*[[Interleukin 3D structures\|Interleukin 3D structures]]
		+	*[[Interleukin receptor 3D structures\|Interleukin receptor 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Broughton~~, S E~~]]	+	[[Category: Broughton SE]]
-	[[Category: Dhagat, U]]	+	[[Category: Dhagat U]]
-	[[Category: Hercus~~, T R~~]]	+	[[Category: Hercus TR]]
-	[[Category: Kan~~, W L~~]]	+	[[Category: Kan WL]]
-	[[Category: Lopez~~, A F~~]]	+	[[Category: Lopez AF]]
-	[[Category: Nero~~, T L~~]]	+	[[Category: Nero TL]]
-	[[Category: Parker~~, M W]]~~	+	[[Category: Parker MW]]
-	~~[[Category: Cell surface]]~~	+
-	~~[[Category: Cytokine]]~~	+
-	~~[[Category: Cytokine-receptor complex]]~~	+
-	~~[[Category: Receptor assembly~~]]	+

OCA at 16:11, 22 January 2020

OCA — Wed, 22 Jan 2020 16:11:03 GMT

←Older revision		Revision as of 16:11, 22 January 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6nmy is ~~ON HOLD until Paper Publication~~	+	==A Cytokine-receptor complex==
-		+	<StructureSection load='6nmy' size='340' side='right'caption='[[6nmy]], [[Resolution\|resolution]] 3.30Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6nmy]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NMY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NMY FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nmy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nmy OCA], [http://pdbe.org/6nmy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nmy RCSB], [http://www.ebi.ac.uk/pdbsum/6nmy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nmy ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] Defects in CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5) [MIM:[http://omim.org/entry/614370 614370]]. SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.<ref>PMID:21075760</ref>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. [[http://www.uniprot.org/uniprot/IL3RA_HUMAN IL3RA_HUMAN]] This is a receptor for interleukin-3. [[http://www.uniprot.org/uniprot/IL3_HUMAN IL3_HUMAN]] Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Broughton, S E]]
		+	[[Category: Dhagat, U]]
		+	[[Category: Hercus, T R]]
		+	[[Category: Kan, W L]]
		+	[[Category: Lopez, A F]]
		+	[[Category: Nero, T L]]
		+	[[Category: Parker, M W]]
		+	[[Category: Cell surface]]
		+	[[Category: Cytokine]]
		+	[[Category: Cytokine-receptor complex]]
		+	[[Category: Receptor assembly]]

OCA at 09:20, 13 November 2019

OCA — Wed, 13 Nov 2019 09:20:54 GMT

←Older revision		Revision as of 09:20, 13 November 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6nmy is ON HOLD	+	The entry 6nmy is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6nmy" [edit=sysop:move=sysop]

OCA — Wed, 30 Jan 2019 06:36:50 GMT

Protected "6nmy" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:36, 30 January 2019

OCA: New page: '''Unreleased structure''' The entry 6nmy is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 30 Jan 2019 06:36:49 GMT

New page: '''Unreleased structure''' The entry 6nmy is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6nmy is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]