6noy - Revision history

OCA at 23:09, 5 June 2019

OCA — Wed, 05 Jun 2019 23:09:04 GMT

←Older revision		Revision as of 23:09, 5 June 2019
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	<StructureSection load='6noy' size='340' side='right'caption='[[6noy]], [[Resolution\|resolution]] 3.46Å' scene=''>		<StructureSection load='6noy' size='340' side='right'caption='[[6noy]], [[Resolution\|resolution]] 3.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6noy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NOY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6noy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Cyanothece Cyanothece]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NOY FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PCC7424_5530 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=43988 Cyanothece])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6noy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6noy OCA], [http://pdbe.org/6noy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6noy RCSB], [http://www.ebi.ac.uk/pdbsum/6noy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6noy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6noy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6noy OCA], [http://pdbe.org/6noy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6noy RCSB], [http://www.ebi.ac.uk/pdbsum/6noy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6noy ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Carboxysomes, protein-coated organelles in cyanobacteria, are important in global carbon fixation. However, these organelles are present at low copy in each cell and hence must be segregated to ensure transmission from one generation to the next. Recent studies revealed that a DNA partition-like ParA-ParB system mediates carboxysome maintenance, called McdA-McdB. Here, we describe the first McdA and McdB homolog structures. McdA is similar to partition ParA Walker-box proteins, but lacks the P-loop signature lysine involved in ATP binding. Strikingly, a McdA-ATP structure shows that a lysine distant from the P-loop and conserved in McdA homologs, enables ATP-dependent nucleotide sandwich dimer formation. Similar to partition ParA proteins this ATP-bound form binds nonspecific-DNA. McdB, which we show directly binds McdA, harbors a unique fold and appears to form higher-order oligomers like partition ParB proteins. Thus, our data reveal a new signature motif that enables McdA dimer formation and indicates that, similar to DNA segregation, carboxysome maintenance systems employ Walker-box proteins as DNA-binding motors while McdB proteins form higher order oligomers, which could function as adaptors to link carboxysomes and provide for stable transport by the McdA proteins.
		+
		+	Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs.,Schumacher MA, Henderson M, Zhang H Nucleic Acids Res. 2019 May 20. pii: 5491742. doi: 10.1093/nar/gkz314. PMID:31106331<ref>PMID:31106331</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6noy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Cyanothece]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Schumacher, M A]]		[[Category: Schumacher, M A]]

OCA at 07:02, 24 April 2019

OCA — Wed, 24 Apr 2019 07:02:19 GMT

←Older revision		Revision as of 07:02, 24 April 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6noy is ~~ON HOLD until Paper Publication~~	+	==Structure of Cyanothece McdB==
-		+	<StructureSection load='6noy' size='340' side='right'caption='[[6noy]], [[Resolution\|resolution]] 3.46Å' scene=''>
-	~~Authors~~: ~~Schumacher~~, M.A.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6noy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NOY FirstGlance]. <br>
-	~~Description: Structure of Cyanothece McdB~~	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6noy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6noy OCA], [http://pdbe.org/6noy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6noy RCSB], [http://www.ebi.ac.uk/pdbsum/6noy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6noy ProSAT]</span></td></tr>
-	[[Category: Schumacher, M.A]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Schumacher, M A]]
		+	[[Category: Bmc]]
		+	[[Category: Carboxysome]]
		+	[[Category: Mcda]]
		+	[[Category: Mcdb]]
		+	[[Category: Parb-like]]
		+	[[Category: Structural protein]]

OCA: Protected "6noy" [edit=sysop:move=sysop]

OCA — Wed, 30 Jan 2019 06:41:40 GMT

Protected "6noy" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:41, 30 January 2019

OCA: New page: '''Unreleased structure''' The entry 6noy is ON HOLD until Paper Publication Authors: Schumacher, M.A. Description: Structure of Cyanothece McdB Category: Unreleased Structures [[C...

OCA — Wed, 30 Jan 2019 06:41:39 GMT

New page: '''Unreleased structure''' The entry 6noy is ON HOLD until Paper Publication Authors: Schumacher, M.A. Description: Structure of Cyanothece McdB Category: Unreleased Structures [[C...

New page

'''Unreleased structure'''

The entry 6noy is ON HOLD until Paper Publication

Authors: Schumacher, M.A.

Description: Structure of Cyanothece McdB
[[Category: Unreleased Structures]]
[[Category: Schumacher, M.A]]