6nqq - Revision history

OCA at 06:58, 11 October 2023

OCA — Wed, 11 Oct 2023 06:58:12 GMT

←Older revision		Revision as of 06:58, 11 October 2023
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	<StructureSection load='6nqq' size='340' side='right'caption='[[6nqq]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='6nqq' size='340' side='right'caption='[[6nqq]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nqq]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Echinophyllia_sp.~~_sc22~~ Echinophyllia sp. ~~sc22~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NQQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6NQQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nqq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Echinophyllia_sp._SC22 Echinophyllia sp. SC22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NQQ FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=KZ1:'>KZ1</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~Dronpa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=301887 Echinophyllia sp. SC22~~])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KZ1:{(4Z)-2-[(1R)-1-amino-2-sulfanylethyl]-5-oxo-4-[(2,3,5-trifluoro-4-hydroxyphenyl)methylidene]-4,5-dihydro-1H-imidazol-1-yl}acetic+acid'>KZ1</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca.weizmann~~.~~ac.il/oca-docs~~/fgij/fg.htm?mol=6nqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nqq OCA], [~~http~~://pdbe.org/6nqq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6nqq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6nqq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6nqq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nqq OCA], [https://pdbe.org/6nqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nqq RCSB], [https://www.ebi.ac.uk/pdbsum/6nqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nqq ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q5TLG6_9CNID Q5TLG6_9CNID]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
	*[[Dronpa\|Dronpa]]		*[[Dronpa\|Dronpa]]
		+	*[[Green Fluorescent Protein 3D structures\|Green Fluorescent Protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Echinophyllia sp. ~~sc22~~]]	+	[[Category: Echinophyllia sp. SC22]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Boxer~~, S G~~]]	+	[[Category: Boxer SG]]
-	[[Category: Lin, C Y]]	+	[[Category: Lin C-Y]]
-	[[Category: Mathews~~, I I~~]]	+	[[Category: Mathews II]]
-	[[Category: Romei~~, M G]]~~	+	[[Category: Romei MG]]
-	~~[[Category: Dronpa2]]~~	+
-	~~[[Category: Fluorescent protein~~]]	+

OCA at 09:01, 5 February 2020

OCA — Wed, 05 Feb 2020 09:01:53 GMT

←Older revision		Revision as of 09:01, 5 February 2020
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nqq OCA], [http://pdbe.org/6nqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nqq RCSB], [http://www.ebi.ac.uk/pdbsum/6nqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nqq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nqq OCA], [http://pdbe.org/6nqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nqq RCSB], [http://www.ebi.ac.uk/pdbsum/6nqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nqq ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rotation around a specific bond after photoexcitation is central to vision and emerging opportunities in optogenetics, super-resolution microscopy, and photoactive molecular devices. Competing roles for steric and electrostatic effects that govern bond-specific photoisomerization have been widely discussed, the latter originating from chromophore charge transfer upon excitation. We systematically altered the electrostatic properties of the green fluorescent protein chromophore in a photoswitchable variant, Dronpa2, using amber suppression to introduce electron-donating and electron-withdrawing groups to the phenolate ring. Through analysis of the absorption (color), fluorescence quantum yield, and energy barriers to ground- and excited-state isomerization, we evaluate the contributions of sterics and electrostatics quantitatively and demonstrate how electrostatic effects bias the pathway of chromophore photoisomerization, leading to a generalized framework to guide protein design.
		+
		+	Electrostatic control of photoisomerization pathways in proteins.,Romei MG, Lin CY, Mathews II, Boxer SG Science. 2020 Jan 3;367(6473):76-79. doi: 10.1126/science.aax1898. PMID:31896714<ref>PMID:31896714</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6nqq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Dronpa\|Dronpa]]		*[[Dronpa\|Dronpa]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:04, 25 December 2019

OCA — Wed, 25 Dec 2019 13:04:15 GMT

←Older revision		Revision as of 13:04, 25 December 2019
Line 3:		Line 3:
	<StructureSection load='6nqq' size='340' side='right'caption='[[6nqq]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='6nqq' size='340' side='right'caption='[[6nqq]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nqq]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NQQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nqq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Echinophyllia_sp._sc22 Echinophyllia sp. sc22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NQQ FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KZ1:'>KZ1</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KZ1:'>KZ1</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Dronpa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=301887 Echinophyllia sp. SC22])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nqq OCA], [http://pdbe.org/6nqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nqq RCSB], [http://www.ebi.ac.uk/pdbsum/6nqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nqq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nqq OCA], [http://pdbe.org/6nqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nqq RCSB], [http://www.ebi.ac.uk/pdbsum/6nqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nqq ProSAT]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Dronpa\|Dronpa]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Echinophyllia sp. sc22]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Boxer, S G]]		[[Category: Boxer, S G]]

OCA at 05:41, 12 June 2019

OCA — Wed, 12 Jun 2019 05:41:18 GMT

←Older revision		Revision as of 05:41, 12 June 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6nqq ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of fast switching M159T mutant of fluorescent protein Dronpa (Dronpa2), Y63(2,3,5-F3Y)==
-		+	<StructureSection load='6nqq' size='340' side='right'caption='[[6nqq]], [[Resolution\|resolution]] 2.60Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6nqq]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NQQ FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KZ1:'>KZ1</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nqq OCA], [http://pdbe.org/6nqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nqq RCSB], [http://www.ebi.ac.uk/pdbsum/6nqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nqq ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Boxer, S G]]
		+	[[Category: Lin, C Y]]
		+	[[Category: Mathews, I I]]
		+	[[Category: Romei, M G]]
		+	[[Category: Dronpa2]]
		+	[[Category: Fluorescent protein]]

OCA at 07:37, 13 February 2019

OCA — Wed, 13 Feb 2019 07:37:57 GMT

←Older revision		Revision as of 07:37, 13 February 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6nqq is ON HOLD	+	The entry 6nqq is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6nqq" [edit=sysop:move=sysop]

OCA — Wed, 30 Jan 2019 06:46:56 GMT

Protected "6nqq" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:46, 30 January 2019

OCA: New page: '''Unreleased structure''' The entry 6nqq is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 30 Jan 2019 06:46:54 GMT

New page: '''Unreleased structure''' The entry 6nqq is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6nqq is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]