6nwn - Revision history

OCA at 07:01, 11 October 2023

OCA — Wed, 11 Oct 2023 07:01:02 GMT

←Older revision		Revision as of 07:01, 11 October 2023
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	<StructureSection load='6nwn' size='340' side='right'caption='[[6nwn]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='6nwn' size='340' side='right'caption='[[6nwn]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6nwn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NWN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6NWN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6nwn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NWN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=L6M:5-{[N-({(1S,2R)-2-[4-(carboxymethyl)benzene-1-carbonyl]cyclopentyl}acetyl)-L-gamma-glutamyl]amino}-2,5-dideoxycytidine'>L6M</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.005Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6cve\|6cve]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=L6M:5-{[N-({(1S,2R)-2-[4-(carboxymethyl)benzene-1-carbonyl]cyclopentyl}acetyl)-L-gamma-glutamyl]amino}-2,5-dideoxycytidine'>L6M</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dethiobiotin_synthase Dethiobiotin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.3 6.3.3.3] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nwn OCA], [https://pdbe.org/6nwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nwn RCSB], [https://www.ebi.ac.uk/pdbsum/6nwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nwn ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6nwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nwn OCA], [~~http~~://pdbe.org/6nwn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6nwn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6nwn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6nwn ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU]] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref>	+	[https://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref>
		+
		+	==See Also==
		+	*[[Dethiobiotin synthetase 3D structures\|Dethiobiotin synthetase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Dethiobiotin synthase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bruning, J B~~]]	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	[[Category: ~~Polyak, S W~~]]	+	[[Category: Bruning JB]]
-	[[Category: ~~Thompson, A P~~]]	+	[[Category: Polyak SW]]
-	[[Category: ~~Wegener, K L~~]]	+	[[Category: Thompson AP]]
-	[[Category: ~~Enzyme]]~~	+	[[Category: Wegener KL]]
-	~~[[Category: Nucleotide triphosphate binding]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 04:17, 13 February 2020

OCA — Thu, 13 Feb 2020 04:17:02 GMT

←Older revision		Revision as of 04:17, 13 February 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6nwn is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with glutamic acid linked compound 10==
-		+	<StructureSection load='6nwn' size='340' side='right'caption='[[6nwn]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~Authors~~: ~~Thompson~~, A.P., ~~Polyak, S~~.W., ~~Wegener~~, K.L., ~~Bruning~~, J.B.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6nwn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NWN FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure~~ of ~~Mycobacterium tuberculosis dethiobiotin synthetase in complex with glutamic~~ acid ~~linked compound 10~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=L6M:5-{[N-({(1S,2R)-2-[4-(carboxymethyl)benzene-1-carbonyl]cyclopentyl}acetyl)-L-gamma-glutamyl]amino}-2,5-dideoxycytidine'>L6M</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6cve\|6cve]]</td></tr>
-	[[Category: ~~Polyak, S.W~~]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dethiobiotin_synthase Dethiobiotin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.3 6.3.3.3] </span></td></tr>
-	[[Category: Bruning, J.B]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nwn OCA], [http://pdbe.org/6nwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nwn RCSB], [http://www.ebi.ac.uk/pdbsum/6nwn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nwn ProSAT]</span></td></tr>
-	[[Category: Thompson, A.P]]	+	</table>
-	[[Category: Wegener, K.L]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU]] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Dethiobiotin synthase]]
		+	[[Category: Large Structures]]
		+	[[Category: Bruning, J B]]
		+	[[Category: Polyak, S W]]
		+	[[Category: Thompson, A P]]
		+	[[Category: Wegener, K L]]
		+	[[Category: Enzyme]]
		+	[[Category: Nucleotide triphosphate binding]]
		+	[[Category: Transferase]]

OCA at 05:10, 21 February 2019

OCA — Thu, 21 Feb 2019 05:10:14 GMT

←Older revision		Revision as of 05:10, 21 February 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6nwn is ON HOLD	+	The entry 6nwn is ON HOLD until Paper Publication

	Authors: Thompson, A.P., Polyak, S.W., Wegener, K.L., Bruning, J.B.		Authors: Thompson, A.P., Polyak, S.W., Wegener, K.L., Bruning, J.B.

OCA: Protected "6nwn" [edit=sysop:move=sysop]

OCA — Wed, 13 Feb 2019 07:53:12 GMT

Protected "6nwn" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:53, 13 February 2019

OCA: New page: '''Unreleased structure''' The entry 6nwn is ON HOLD Authors: Thompson, A.P., Polyak, S.W., Wegener, K.L., Bruning, J.B. Description: Crystal structure of Mycobacterium tuberculosis de...

OCA — Wed, 13 Feb 2019 07:53:09 GMT

New page: '''Unreleased structure''' The entry 6nwn is ON HOLD Authors: Thompson, A.P., Polyak, S.W., Wegener, K.L., Bruning, J.B. Description: Crystal structure of Mycobacterium tuberculosis de...

New page

'''Unreleased structure'''

The entry 6nwn is ON HOLD

Authors: Thompson, A.P., Polyak, S.W., Wegener, K.L., Bruning, J.B.

Description: Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with glutamic acid linked compound 10
[[Category: Unreleased Structures]]
[[Category: Polyak, S.W]]
[[Category: Bruning, J.B]]
[[Category: Thompson, A.P]]
[[Category: Wegener, K.L]]