6ove - Revision history

OCA at 07:17, 11 October 2023

OCA — Wed, 11 Oct 2023 07:17:50 GMT

←Older revision		Revision as of 07:17, 11 October 2023
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	==Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC==		==Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC==
-	<StructureSection load='6ove' size='340' side='right'caption='[[6ove]]' scene=''>	+	<StructureSection load='6ove' size='340' side='right'caption='[[6ove]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OVE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6OVE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ove]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OVE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6ove FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ove OCA], [~~http~~://pdbe.org/6ove PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ove RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ove PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ove ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=N9D:(3R,5S)-5-[(2R)-2-amino-2-carboxyethyl]-1-(4-propylphenyl)pyrazolidine-3-carboxylic+acid'>N9D</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ove FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ove OCA], [https://pdbe.org/6ove PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ove RCSB], [https://www.ebi.ac.uk/pdbsum/6ove PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ove ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/NMDZ1_RAT NMDZ1_RAT] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.<ref>PMID:15996549</ref>
		+
		+	==See Also==
		+	*[[Glutamate receptor 3D structures\|Glutamate receptor 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Rattus norvegicus]]
	[[Category: Hansen KB]]		[[Category: Hansen KB]]
	[[Category: Mou TC]]		[[Category: Mou TC]]

OCA at 05:27, 13 May 2020

OCA — Wed, 13 May 2020 05:27:11 GMT

←Older revision		Revision as of 05:27, 13 May 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6ove ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC==
-		+	<StructureSection load='6ove' size='340' side='right'caption='[[6ove]]' scene=''>
-	~~Authors~~: ~~Syrenne, J~~.T., ~~Mou, T~~.C., ~~Tamborini, L~~., ~~Pinto, A~~., ~~Sprang, S~~.R., ~~Hansen, K~~.B.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OVE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6OVE FirstGlance]. <br>
-	~~Description: Crystal structure of GluN1~~/~~GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ove FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ove OCA], [http://pdbe.org/6ove PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ove RCSB], [http://www.ebi.ac.uk/pdbsum/6ove PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ove ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Syrenne, J.T~~]]	+	__TOC__
-	[[Category: ~~Pinto, A~~]]	+	</StructureSection>
-	[[Category: ~~Mou, T.C~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Hansen, K.B~~]]	+	[[Category: Hansen KB]]
-	[[Category: ~~Tamborini, L~~]]	+	[[Category: Mou TC]]
-	[[Category: ~~Sprang, S.R~~]]	+	[[Category: Pinto A]]
		+	[[Category: Sprang SR]]
		+	[[Category: Syrenne JT]]
		+	[[Category: Tamborini L]]

OCA: Protected "6ove" [edit=sysop:move=sysop]

OCA — Tue, 21 May 2019 05:52:06 GMT

Protected "6ove" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:52, 21 May 2019

OCA: New page: '''Unreleased structure''' The entry 6ove is ON HOLD until Paper Publication Authors: Syrenne, J.T., Mou, T.C., Tamborini, L., Pinto, A., Sprang, S.R., Hansen, K.B. Description: Crysta...

OCA — Tue, 21 May 2019 05:52:05 GMT

New page: '''Unreleased structure''' The entry 6ove is ON HOLD until Paper Publication Authors: Syrenne, J.T., Mou, T.C., Tamborini, L., Pinto, A., Sprang, S.R., Hansen, K.B. Description: Crysta...

New page

'''Unreleased structure'''

The entry 6ove is ON HOLD until Paper Publication

Authors: Syrenne, J.T., Mou, T.C., Tamborini, L., Pinto, A., Sprang, S.R., Hansen, K.B.

Description: Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC
[[Category: Unreleased Structures]]
[[Category: Syrenne, J.T]]
[[Category: Pinto, A]]
[[Category: Mou, T.C]]
[[Category: Hansen, K.B]]
[[Category: Tamborini, L]]
[[Category: Sprang, S.R]]