6p0n - Revision history

OCA at 07:20, 11 October 2023

OCA — Wed, 11 Oct 2023 07:20:43 GMT

←Older revision		Revision as of 07:20, 11 October 2023
Line 3:		Line 3:
	<StructureSection load='6p0n' size='340' side='right'caption='[[6p0n]], [[Resolution\|resolution]] 1.63Å' scene=''>		<StructureSection load='6p0n' size='340' side='right'caption='[[6p0n]], [[Resolution\|resolution]] 1.63Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6p0n]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P0N OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6P0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6p0n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P0N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NLS:4-[(6-fluoropyridin-2-yl)sulfamoyl]benzene-1-sulfonic+acid'>NLS</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.63Å</td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RALA, RAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NLS:4-[(6-fluoropyridin-2-yl)sulfamoyl]benzene-1-sulfonic+acid'>NLS</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6p0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p0n OCA], [~~http~~://pdbe.org/6p0n PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6p0n RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6p0n PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6p0n ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p0n OCA], [https://pdbe.org/6p0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p0n RCSB], [https://www.ebi.ac.uk/pdbsum/6p0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p0n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RALA_HUMAN RALA_HUMAN]] Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.<ref>PMID:18756269</ref> <ref>PMID:19306925</ref> <ref>PMID:20005108</ref>	+	[https://www.uniprot.org/uniprot/RALA_HUMAN RALA_HUMAN] Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.<ref>PMID:18756269</ref> <ref>PMID:19306925</ref> <ref>PMID:20005108</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bum-Erdene, K]]	+	[[Category: Bum-Erdene K]]
-	[[Category: Ghozayel~~, M K~~]]	+	[[Category: Ghozayel MK]]
-	[[Category: Gonzalez-Gutierrez, G]]	+	[[Category: Gonzalez-Gutierrez G]]
-	[[Category: Liu, D]]	+	[[Category: Liu D]]
-	[[Category: Meroueh~~, S O~~]]	+	[[Category: Meroueh SO]]
-	[[Category: Xu, D]]	+	[[Category: Xu D]]
-	~~[[Category: Covalent inhibitor]]~~	+
-	~~[[Category: Ral gtpase]]~~	+
-	~~[[Category: Rala]]~~	+
-	~~[[Category: Signaling protein]]~~	+
-	~~[[Category: Signaling protein-inhibitor complex]]~~	+
-	~~[[Category: Sulfonyl fluoride~~]]	+

OCA at 07:14, 15 April 2020

OCA — Wed, 15 Apr 2020 07:14:44 GMT

←Older revision		Revision as of 07:14, 15 April 2020
Line 3:		Line 3:
	<StructureSection load='6p0n' size='340' side='right'caption='[[6p0n]], [[Resolution\|resolution]] 1.63Å' scene=''>		<StructureSection load='6p0n' size='340' side='right'caption='[[6p0n]], [[Resolution\|resolution]] 1.63Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6p0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P0N OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6P0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6p0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P0N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6P0N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NLS:4-[(6-fluoropyridin-2-yl)sulfamoyl]benzene-1-sulfonic+acid'>NLS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NLS:4-[(6-fluoropyridin-2-yl)sulfamoyl]benzene-1-sulfonic+acid'>NLS</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RALA, RAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RALA, RAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6p0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p0n OCA], [http://pdbe.org/6p0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p0n RCSB], [http://www.ebi.ac.uk/pdbsum/6p0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p0n ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6p0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p0n OCA], [http://pdbe.org/6p0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p0n RCSB], [http://www.ebi.ac.uk/pdbsum/6p0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p0n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 09:37, 1 April 2020

OCA — Wed, 01 Apr 2020 09:37:35 GMT

←Older revision		Revision as of 09:37, 1 April 2020
Line 3:		Line 3:
	<StructureSection load='6p0n' size='340' side='right'caption='[[6p0n]], [[Resolution\|resolution]] 1.63Å' scene=''>		<StructureSection load='6p0n' size='340' side='right'caption='[[6p0n]], [[Resolution\|resolution]] 1.63Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6p0n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6p0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P0N FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NLS:4-[(6-fluoropyridin-2-yl)sulfamoyl]benzene-1-sulfonic+acid'>NLS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NLS:4-[(6-fluoropyridin-2-yl)sulfamoyl]benzene-1-sulfonic+acid'>NLS</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RALA, RAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p0n OCA], [http://pdbe.org/6p0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p0n RCSB], [http://www.ebi.ac.uk/pdbsum/6p0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p0n ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p0n OCA], [http://pdbe.org/6p0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p0n RCSB], [http://www.ebi.ac.uk/pdbsum/6p0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p0n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/RALA_HUMAN RALA_HUMAN]] Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.<ref>PMID:18756269</ref> <ref>PMID:19306925</ref> <ref>PMID:20005108</ref>		[[http://www.uniprot.org/uniprot/RALA_HUMAN RALA_HUMAN]] Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.<ref>PMID:18756269</ref> <ref>PMID:19306925</ref> <ref>PMID:20005108</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ral (Ras-like) GTPases are directly activated by oncogenic Ras GTPases. Mutant K-Ras (G12C) has enabled the development of covalent K-Ras inhibitors currently in clinical trials. However, Ral, and the overwhelming majority of mutant oncogenic K-Ras, are devoid of a druggable pocket and lack an accessible cysteine for the development of a covalent inhibitor. Here, we report that covalent bond formation by an aryl sulfonyl fluoride electrophile at a tyrosine residue (Tyr-82) inhibits guanine exchange factor Rgl2-mediated nucleotide exchange of Ral GTPase. A high-resolution 1.18-A X-ray cocrystal structure shows that the compound binds to a well-defined binding site in RalA as a result of a switch II loop conformational change. The structure, along with additional high-resolution crystal structures of several analogs in complex with RalA, confirm the importance of key hydrogen bond anchors between compound sulfone oxygen atoms and Ral backbone nitrogen atoms. Our discovery of a pocket with features found on known druggable sites and covalent modification of a bystander tyrosine residue present in Ral and Ras GTPases provide a strategy that could lead to therapeutic agent targeting oncogenic Ras mutants that are devoid of a cysteine nucleophile.
		+
		+	Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases.,Bum-Erdene K, Liu D, Gonzalez-Gutierrez G, Ghozayel MK, Xu D, Meroueh SO Proc Natl Acad Sci U S A. 2020 Mar 16. pii: 1913654117. doi:, 10.1073/pnas.1913654117. PMID:32179690<ref>PMID:32179690</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6p0n" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bum-Erdene, K]]		[[Category: Bum-Erdene, K]]

OCA at 06:44, 4 March 2020

OCA — Wed, 04 Mar 2020 06:44:53 GMT

←Older revision		Revision as of 06:44, 4 March 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6p0n ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of GDP-bound human RalA in a covalent complex with aryl sulfonyl fluoride compounds.==
-		+	<StructureSection load='6p0n' size='340' side='right'caption='[[6p0n]], [[Resolution\|resolution]] 1.63Å' scene=''>
-	~~Authors~~: ~~Bum~~-~~Erdene, K~~., ~~Gonzalez~~-~~Gutierrez~~, G., ~~Liu~~, D., ~~Ghozayel, M~~.K., ~~Xu, D~~., ~~Meroueh, S~~.O.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6p0n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P0N FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure~~ of ~~GDP~~-~~bound human RalA in~~ a ~~covalent~~ complex with ~~aryl sulfonyl fluoride compounds~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NLS:4-[(6-fluoropyridin-2-yl)sulfamoyl]benzene-1-sulfonic+acid'>NLS</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p0n OCA], [http://pdbe.org/6p0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p0n RCSB], [http://www.ebi.ac.uk/pdbsum/6p0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p0n ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RALA_HUMAN RALA_HUMAN]] Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with ADRBK1 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.<ref>PMID:18756269</ref> <ref>PMID:19306925</ref> <ref>PMID:20005108</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Bum-Erdene, K]]
		+	[[Category: Ghozayel, M K]]
		+	[[Category: Gonzalez-Gutierrez, G]]
	[[Category: Liu, D]]		[[Category: Liu, D]]
-	[[Category: Meroueh, S.O]]	+	[[Category: Meroueh, S O]]
	[[Category: Xu, D]]		[[Category: Xu, D]]
-	[[Category: ~~Ghozayel, M.K~~]]	+	[[Category: Covalent inhibitor]]
-	[[Category: ~~Bum-Erdene, K~~]]	+	[[Category: Ral gtpase]]
-	[[Category: ~~Gonzalez~~-~~Gutierrez, G~~]]	+	[[Category: Rala]]
		+	[[Category: Signaling protein]]
		+	[[Category: Signaling protein-inhibitor complex]]
		+	[[Category: Sulfonyl fluoride]]

OCA: Protected "6p0n" [edit=sysop:move=sysop]

OCA — Wed, 29 May 2019 04:33:34 GMT

Protected "6p0n" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:33, 29 May 2019

OCA: New page: '''Unreleased structure''' The entry 6p0n is ON HOLD until Paper Publication Authors: Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O. Description...

OCA — Wed, 29 May 2019 04:33:33 GMT

New page: '''Unreleased structure''' The entry 6p0n is ON HOLD until Paper Publication Authors: Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O. Description...

New page

'''Unreleased structure'''

The entry 6p0n is ON HOLD until Paper Publication

Authors: Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O.

Description: Crystal structure of GDP-bound human RalA in a covalent complex with aryl sulfonyl fluoride compounds.
[[Category: Unreleased Structures]]
[[Category: Liu, D]]
[[Category: Meroueh, S.O]]
[[Category: Xu, D]]
[[Category: Ghozayel, M.K]]
[[Category: Bum-Erdene, K]]
[[Category: Gonzalez-Gutierrez, G]]