6pfn - Revision history

OCA at 07:28, 11 October 2023

OCA — Wed, 11 Oct 2023 07:28:29 GMT

←Older revision		Revision as of 07:28, 11 October 2023
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	<StructureSection load='6pfn' size='340' side='right'caption='[[6pfn]], [[Resolution\|resolution]] 1.76Å' scene=''>		<StructureSection load='6pfn' size='340' side='right'caption='[[6pfn]], [[Resolution\|resolution]] 1.76Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6pfn]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Fratt Fratt~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PFN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6PFN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6pfn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis_SCHU_S4 Francisella tularensis subsp. tularensis SCHU S4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PFN FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.76Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Related_structure~~\|~~Related:]]</b></td><td class="sblockDat">[[6mgg\|6mgg~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~sucD, BZ14_337 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=177416 FRATT]), sucC, FTT_0504c ([http~~:~~//www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 FRATT])</td~~></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pfn OCA], [https://pdbe.org/6pfn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pfn RCSB], [https://www.ebi.ac.uk/pdbsum/6pfn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pfn ProSAT]</span></td></tr>
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[http~~:~~//en.wikipedia.org/wiki/Succinate--CoA_ligase_(ADP-forming) Succinate--CoA ligase (ADP-forming)]~~, ~~with EC number [http://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=6.2.1.5 6.2.1.5]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6pfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pfn OCA], [~~http~~://pdbe.org/6pfn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6pfn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6pfn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6pfn ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~A0A454XSD0_FRATT A0A454XSD0_FRATT]~~] Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.[HAMAP-Rule:MF_01988][RuleBase:RU000699] [[~~http://www.uniprot.org/uniprot/SUCC_FRATT SUCC_FRATT]]~~ Succinyl-CoA synthetase ~~functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl~~-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	+	[https://www.uniprot.org/uniprot/Q5NHF4_FRATT Q5NHF4_FRATT] Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.[HAMAP-Rule:MF_01988][RuleBase:RU000699]
		+
		+	==See Also==
		+	*[[Succinyl-CoA synthetase 3D structures\|Succinyl-CoA synthetase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Fratt~~]]	+	[[Category: Francisella tularensis subsp. tularensis SCHU S4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Structural genomic]]~~	+	[[Category: Jedrzejczak R]]
-	[[Category: Jedrzejczak, R]]	+	[[Category: Joachimiak A]]
-	[[Category: Joachimiak, A]]	+	[[Category: Maltseva N]]
-	[[Category: Maltseva, N]]	+	[[Category: Osipiuk J]]
-	[[Category: Osipiuk, J]]	+	[[Category: Satchell KJF]]
-	[[Category: Satchell~~, K J.F]]~~	+
-	~~[[Category: Cpx_02187_02692]]~~	+
-	~~[[Category: Csgid]]~~	+
-	~~[[Category: Idp02187]]~~	+
-	~~[[Category: Idp02692]]~~	+
-	~~[[Category: Ligase]]~~	+
-	~~[[Category: Succinyl-coa synthase~~]]	+

OCA at 12:25, 18 December 2019

OCA — Wed, 18 Dec 2019 12:25:53 GMT

←Older revision		Revision as of 12:25, 18 December 2019
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	<StructureSection load='6pfn' size='340' side='right'caption='[[6pfn]], [[Resolution\|resolution]] 1.76Å' scene=''>		<StructureSection load='6pfn' size='340' side='right'caption='[[6pfn]], [[Resolution\|resolution]] 1.76Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6pfn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PFN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6pfn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Fratt Fratt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PFN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6mgg\|6mgg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6mgg\|6mgg]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sucD, BZ14_337 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 FRATT]), sucC, FTT_0504c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 FRATT])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Succinate--CoA_ligase_(ADP-forming) Succinate--CoA ligase (ADP-forming)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.2.1.5 6.2.1.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Succinate--CoA_ligase_(ADP-forming) Succinate--CoA ligase (ADP-forming)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.2.1.5 6.2.1.5] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pfn OCA], [http://pdbe.org/6pfn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pfn RCSB], [http://www.ebi.ac.uk/pdbsum/6pfn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pfn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pfn OCA], [http://pdbe.org/6pfn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pfn RCSB], [http://www.ebi.ac.uk/pdbsum/6pfn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pfn ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Fratt]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA: Protected "6pfn" [edit=sysop:move=sysop]

OCA — Wed, 03 Jul 2019 06:00:12 GMT

Protected "6pfn" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:00, 3 July 2019

OCA: New page: ==Succinyl-CoA synthase from Francisella tularensis== == Structura...

OCA — Wed, 03 Jul 2019 06:00:10 GMT

New page: ==Succinyl-CoA synthase from Francisella tularensis== <StructureSection load='6pfn' size='340' side='right'caption='6pfn, resolution 1.76Å' scene=''> == Structura...

New page

==Succinyl-CoA synthase from Francisella tularensis==
<StructureSection load='6pfn' size='340' side='right'caption='[[6pfn]], [[Resolution|resolution]] 1.76Å' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6pfn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PFN OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PFN FirstGlance]. 
</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6mgg|6mgg]]</td></tr>
<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Succinate--CoA_ligase_(ADP-forming) Succinate--CoA ligase (ADP-forming)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.2.1.5 6.2.1.5] </td></tr>
<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pfn OCA], [http://pdbe.org/6pfn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pfn RCSB], [http://www.ebi.ac.uk/pdbsum/6pfn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pfn ProSAT]</td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/A0A454XSD0_FRATT A0A454XSD0_FRATT]] Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.[HAMAP-Rule:MF_01988][RuleBase:RU000699] [[http://www.uniprot.org/uniprot/SUCC_FRATT SUCC_FRATT]] Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Jedrzejczak, R]]
[[Category: Joachimiak, A]]
[[Category: Maltseva, N]]
[[Category: Osipiuk, J]]
[[Category: Satchell, K J.F]]
[[Category: Cpx_02187_02692]]
[[Category: Csgid]]
[[Category: Idp02187]]
[[Category: Idp02692]]
[[Category: Ligase]]
[[Category: Succinyl-coa synthase]]