6pjj - Revision history

OCA at 07:30, 11 October 2023

OCA — Wed, 11 Oct 2023 07:30:44 GMT

←Older revision		Revision as of 07:30, 11 October 2023
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	<StructureSection load='6pjj' size='340' side='right'caption='[[6pjj]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='6pjj' size='340' side='right'caption='[[6pjj]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6pjj]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PJJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6PJJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6pjj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PJJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCJ:4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OCJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene~~></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCJ:4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OCJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pjj OCA], [https://pdbe.org/6pjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pjj RCSB], [https://www.ebi.ac.uk/pdbsum/6pjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pjj ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6pjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pjj OCA], [~~http~~://pdbe.org/6pjj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6pjj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6pjj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6pjj ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN]] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.	+	[https://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Non-specific serine/threonine protein kinase]]~~	+	[[Category: Arruda P]]
-	[[Category: Arruda, P]]	+	[[Category: Azevedo H]]
-	[[Category: Azevedo, H]]	+	[[Category: Counago RM]]
-	[[Category: Counago~~, R M~~]]	+	[[Category: Elkins JM]]
-	[[Category: Elkins~~, J M~~]]	+	[[Category: Fala AM]]
-	[[Category: Fala~~, A M~~]]	+	[[Category: Godoi PHC]]
-	[[Category: Godoi~~, P H.C~~]]	+	[[Category: Guimaraes CRW]]
-	[[Category: Guimaraes~~, C R.W~~]]	+	[[Category: Mascarello A]]
-	[[Category: Mascarello, A]]	+	[[Category: Ramos PZ]]
-	[[Category: Ramos~~, P Z]]~~	+	[[Category: Santiago AS]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Segretti N]]
-	[[Category: Santiago~~, A S~~]]	+	[[Category: Sriranganadane D]]
-	[[Category: Segretti, N]]	+
-	[[Category: Sriranganadane, D]]	+
-	~~[[Category: Serine/threonine-protein kinase prp4 homolog]]~~	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Splicing kinase prpf4b]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transferase-transferase inhibitor complex~~]]	+

OCA at 12:06, 1 January 2020

OCA — Wed, 01 Jan 2020 12:06:14 GMT

←Older revision		Revision as of 12:06, 1 January 2020
Line 3:		Line 3:
	<StructureSection load='6pjj' size='340' side='right'caption='[[6pjj]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='6pjj' size='340' side='right'caption='[[6pjj]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6pjj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PJJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6pjj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PJJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCJ:4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OCJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCJ:4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OCJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pjj OCA], [http://pdbe.org/6pjj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pjj RCSB], [http://www.ebi.ac.uk/pdbsum/6pjj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pjj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pjj OCA], [http://pdbe.org/6pjj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pjj RCSB], [http://www.ebi.ac.uk/pdbsum/6pjj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pjj ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]

OCA at 15:33, 28 August 2019

OCA — Wed, 28 Aug 2019 15:33:26 GMT

←Older revision		Revision as of 15:33, 28 August 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6pjj ~~is ON HOLD~~	+	==Human PRPF4B bound to benzothiophene inhibitor 224==
-		+	<StructureSection load='6pjj' size='340' side='right'caption='[[6pjj]], [[Resolution\|resolution]] 2.40Å' scene=''>
-	~~Authors~~: ~~Godoi, P~~.H.C.~~, Santiago, A~~.S.~~, Fala, A~~.M.~~, Ramos, P~~.Z., ~~Sriranganadane~~, D., ~~Mascarello, A~~.~~, Segretti, N~~., ~~Azevedo, H~~.~~, Guimaraes, C~~.R.W.~~, Arruda, P~~.~~, Elkins, J~~.M.~~, Counago, R~~.M.~~, Structural Genomics Consortium (SGC)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6pjj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PJJ FirstGlance]. <br>
-	~~Description~~: ~~Human PRPF4B bound to benzothiophene inhibitor 224~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCJ:4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OCJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
-	[[~~Category~~: ~~Fala~~, A.M]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	[[~~Category~~: ~~Elkins, J~~.M]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pjj OCA], [http://pdbe.org/6pjj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pjj RCSB], [http://www.ebi.ac.uk/pdbsum/6pjj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pjj ProSAT]</span></td></tr>
-	[[Category: ~~Guimaraes, C.R.W~~]]	+	</table>
-	[[Category: ~~Segretti, N~~]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN]] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Arruda, P]]		[[Category: Arruda, P]]
-	[[Category: Structural Genomics Consortium (Sgc)]]
-	[[Category: Santiago, A.S]]
-	[[Category: Sriranganadane, D]]
	[[Category: Azevedo, H]]		[[Category: Azevedo, H]]
		+	[[Category: Counago, R M]]
		+	[[Category: Elkins, J M]]
		+	[[Category: Fala, A M]]
		+	[[Category: Godoi, P H.C]]
		+	[[Category: Guimaraes, C R.W]]
	[[Category: Mascarello, A]]		[[Category: Mascarello, A]]
-	[[Category: ~~Counago~~, ~~R.M~~]]	+	[[Category: Ramos, P Z]]
-	[[Category: ~~Ramos~~, ~~P.Z~~]]	+	[[Category: Structural genomic]]
-	[[Category: ~~Godoi~~, ~~P.H.C~~]]	+	[[Category: Santiago, A S]]
		+	[[Category: Segretti, N]]
		+	[[Category: Sriranganadane, D]]
		+	[[Category: Serine/threonine-protein kinase prp4 homolog]]
		+	[[Category: Sgc]]
		+	[[Category: Splicing kinase prpf4b]]
		+	[[Category: Transferase]]
		+	[[Category: Transferase-transferase inhibitor complex]]

OCA: Protected "6pjj" [edit=sysop:move=sysop]

OCA — Wed, 10 Jul 2019 04:08:53 GMT

Protected "6pjj" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:08, 10 July 2019

OCA: New page: '''Unreleased structure''' The entry 6pjj is ON HOLD Authors: Godoi, P.H.C., Santiago, A.S., Fala, A.M., Ramos, P.Z., Sriranganadane, D., Mascarello, A., Segretti, N., Azevedo, H., Guim...

OCA — Wed, 10 Jul 2019 04:08:52 GMT

New page: '''Unreleased structure''' The entry 6pjj is ON HOLD Authors: Godoi, P.H.C., Santiago, A.S., Fala, A.M., Ramos, P.Z., Sriranganadane, D., Mascarello, A., Segretti, N., Azevedo, H., Guim...

New page

'''Unreleased structure'''

The entry 6pjj is ON HOLD

Authors: Godoi, P.H.C., Santiago, A.S., Fala, A.M., Ramos, P.Z., Sriranganadane, D., Mascarello, A., Segretti, N., Azevedo, H., Guimaraes, C.R.W., Arruda, P., Elkins, J.M., Counago, R.M., Structural Genomics Consortium (SGC)

Description: Human PRPF4B bound to benzothiophene inhibitor 224
[[Category: Unreleased Structures]]
[[Category: Fala, A.M]]
[[Category: Elkins, J.M]]
[[Category: Guimaraes, C.R.W]]
[[Category: Segretti, N]]
[[Category: Arruda, P]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Santiago, A.S]]
[[Category: Sriranganadane, D]]
[[Category: Azevedo, H]]
[[Category: Mascarello, A]]
[[Category: Counago, R.M]]
[[Category: Ramos, P.Z]]
[[Category: Godoi, P.H.C]]