6pk2 - Revision history

OCA at 14:55, 13 March 2024

OCA — Wed, 13 Mar 2024 14:55:06 GMT

←Older revision		Revision as of 14:55, 13 March 2024
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS==		==CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS==
-	<StructureSection load='6pk2' size='340' side='right'caption='[[6pk2]]' scene=''>	+	<StructureSection load='6pk2' size='340' side='right'caption='[[6pk2]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PK2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6pk2]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PK2 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pk2 OCA], [https://pdbe.org/6pk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pk2 RCSB], [https://www.ebi.ac.uk/pdbsum/6pk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pk2 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.402Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ORJ:2-{4-[(6-fluoro-1,3-benzothiazol-2-yl)oxy]-2-hydroxyphenyl}-N-methylacetamide'>ORJ</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pk2 OCA], [https://pdbe.org/6pk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pk2 RCSB], [https://www.ebi.ac.uk/pdbsum/6pk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pk2 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ACCD6_MYCTU ACCD6_MYCTU] Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269). When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269).<ref>PMID:17114269</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Mycobacterium tuberculosis]]
	[[Category: Michele TCB]]		[[Category: Michele TCB]]
	[[Category: Nian Z]]		[[Category: Nian Z]]
	[[Category: Reddy MCM]]		[[Category: Reddy MCM]]
	[[Category: Sacchettini JC]]		[[Category: Sacchettini JC]]

OCA at 08:54, 18 February 2021

OCA — Thu, 18 Feb 2021 08:54:15 GMT

←Older revision		Revision as of 08:54, 18 February 2021
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6pk2 is ON HOLD until Paper Publication~~	+	==CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS==
-		+	<StructureSection load='6pk2' size='340' side='right'caption='[[6pk2]]' scene=''>
-	~~Authors: Reddy, M.C.M., Nian, Z., Michele, T.C.B., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PK2 FirstGlance]. <br>
-	~~Description:~~ CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pk2 OCA], [https://pdbe.org/6pk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pk2 RCSB], [https://www.ebi.ac.uk/pdbsum/6pk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pk2 ProSAT]</span></td></tr>
-	[[~~Category: Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Michele~~, T.C.B]]	+	__TOC__
-	[[~~Category~~: ~~Reddy~~, M.C.M]]	+	</StructureSection>
-	[[Category: Nian, Z]]	+	[[Category: Large Structures]]
-	[[Category: ~~Sacchettini, J.C~~]]	+	[[Category: Michele TCB]]
-	[[Category: ~~Tb Structural Genomics Consortium (Tbsgc)~~]]	+	[[Category: Nian Z]]
		+	[[Category: Reddy MCM]]
		+	[[Category: Sacchettini JC]]

OCA at 15:00, 14 August 2019

OCA — Wed, 14 Aug 2019 15:00:07 GMT

←Older revision		Revision as of 15:00, 14 August 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6pk2 is ON HOLD	+	The entry 6pk2 is ON HOLD until Paper Publication

	Authors: Reddy, M.C.M., Nian, Z., Michele, T.C.B., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)		Authors: Reddy, M.C.M., Nian, Z., Michele, T.C.B., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

OCA: Protected "6pk2" [edit=sysop:move=sysop]

OCA — Wed, 10 Jul 2019 04:10:08 GMT

Protected "6pk2" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:10, 10 July 2019

OCA: New page: '''Unreleased structure''' The entry 6pk2 is ON HOLD Authors: Reddy, M.C.M., Nian, Z., Michele, T.C.B., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) Description: CRYSTA...

OCA — Wed, 10 Jul 2019 04:10:07 GMT

New page: '''Unreleased structure''' The entry 6pk2 is ON HOLD Authors: Reddy, M.C.M., Nian, Z., Michele, T.C.B., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC) Description: CRYSTA...

New page

'''Unreleased structure'''

The entry 6pk2 is ON HOLD

Authors: Reddy, M.C.M., Nian, Z., Michele, T.C.B., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

Description: CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS
[[Category: Unreleased Structures]]
[[Category: Michele, T.C.B]]
[[Category: Reddy, M.C.M]]
[[Category: Nian, Z]]
[[Category: Sacchettini, J.C]]
[[Category: Tb Structural Genomics Consortium (Tbsgc)]]