6pz9 - Revision history

OCA at 09:27, 20 March 2024

OCA — Wed, 20 Mar 2024 09:27:56 GMT

←Older revision		Revision as of 09:27, 20 March 2024
Line 3:		Line 3:
	<SX load='6pz9' size='340' side='right' viewer='molstar' caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>		<SX load='6pz9' size='340' side='right' viewer='molstar' caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Black-bellied_hamster Black-bellied hamster~~] and [~~http~~://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cricetus_cricetus Cricetus cricetus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>~~, ~~<scene name='pdbligand=BJX:Repaglinide'>BJX</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.65Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~ABCC8, SUR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=5~~&id=10034 Black~~-~~bellied hamster])~~, ~~Kcnj11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=10116 Buffalo rat])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BJX:Repaglinide'>BJX</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6pz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz9 OCA], [~~http~~://pdbe.org/6pz9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6pz9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6pz9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz9 OCA], [https://pdbe.org/6pz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pz9 RCSB], [https://www.ebi.ac.uk/pdbsum/6pz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ABCC8_CRICR ABCC8_CRICR]] Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive potassium channels and insulin release.[UniProtKB:Q09428] [[http://www.uniprot.org/uniprot/KCJ11_RAT KCJ11_RAT]] This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (By similarity).	+	[https://www.uniprot.org/uniprot/ABCC8_CRICR ABCC8_CRICR] Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive potassium channels and insulin release.[UniProtKB:Q09428]
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	ATP-sensitive potassium (KATP) channels composed of a pore-forming Kir6.2 potassium channel and a regulatory ABC transporter sulfonylurea receptor 1 (SUR1) regulate insulin secretion in pancreatic beta-cells to maintain glucose homeostasis. Mutations that impair channel folding or assembly prevent cell surface expression and cause congenital hyperinsulinism. Structurally diverse KATP inhibitors are known to act as pharmacochaperones to correct mutant channel expression, but the mechanism is unknown. Here, we compare cryoEM structures of a mammalian KATP channel bound to pharmacochaperones glibenclamide, repaglinide, and carbamazepine. We found all three drugs bind within a common pocket in SUR1. Further, we found the N-terminus of Kir6.2 inserted within the central cavity of the SUR1 ABC core, adjacent the drug binding pocket. The findings reveal a common mechanism by which diverse compounds stabilize the Kir6.2 N-terminus within SUR1's ABC core, allowing it to act as a firm 'handle' for the assembly of metastable mutant SUR1-Kir6.2 complexes.	+
-		+
-	Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM.,Martin GM, Sung MW, Yang Z, Innes LM, Kandasamy B, David LL, Yoshioka C, Shyng SL Elife. 2019 Jul 25;8. pii: 46417. doi: 10.7554/eLife.46417. PMID:31343405<ref>PMID:31343405</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 6pz9" style="background-color:#fffaf0;"></div>~~	+

	==See Also==		==See Also==
	*[[Potassium channel 3D structures\|Potassium channel 3D structures]]		*[[Potassium channel 3D structures\|Potassium channel 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: ~~Black-bellied hamster]]~~	+	[[Category: Cricetus cricetus]]
-	~~[[Category: Buffalo rat~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Martin, G M~~]]	+	[[Category: Rattus norvegicus]]
-	[[Category: ~~Shyng, S L~~]]	+	[[Category: Martin GM]]
-	[[Category: ~~Sung, M W~~]]	+	[[Category: Shyng SL]]
-	[[Category: ~~Yoshioka, C~~]]	+	[[Category: Sung MW]]
-	[[Category: ~~Katp]]~~	+	[[Category: Yoshioka C]]
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Rpg]]~~	+
-	~~[[Category: Sur1~~]]	+

OCA at 04:44, 11 April 2020

OCA — Sat, 11 Apr 2020 04:44:12 GMT

←Older revision		Revision as of 04:44, 11 April 2020
Line 3:		Line 3:
	<SX load='6pz9' size='340' side='right' viewer='molstar' caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>		<SX load='6pz9' size='340' side='right' viewer='molstar' caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black-bellied_hamster Black-bellied hamster] and [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black-bellied_hamster Black-bellied hamster] and [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BJX:Repaglinide'>BJX</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BJX:Repaglinide'>BJX</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ABCC8, SUR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10034 Black-bellied hamster]), Kcnj11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ABCC8, SUR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10034 Black-bellied hamster]), Kcnj11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6pz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz9 OCA], [http://pdbe.org/6pz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pz9 RCSB], [http://www.ebi.ac.uk/pdbsum/6pz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6pz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz9 OCA], [http://pdbe.org/6pz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pz9 RCSB], [http://www.ebi.ac.uk/pdbsum/6pz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 23:31, 6 March 2020

OCA — Fri, 06 Mar 2020 23:31:06 GMT

←Older revision		Revision as of 23:31, 6 March 2020
Line 1:		Line 1:

	==Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide==		==Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide==
-	<~~StructureSection~~ load='6pz9' size='340' side='right'caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>	+	<SX load='6pz9' size='340' side='right' viewer='molstar' caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black-bellied_hamster Black-bellied hamster] and [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black-bellied_hamster Black-bellied hamster] and [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>
Line 25:		Line 25:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Black-bellied hamster]]		[[Category: Black-bellied hamster]]
	[[Category: Buffalo rat]]		[[Category: Buffalo rat]]

OCA at 13:09, 25 December 2019

OCA — Wed, 25 Dec 2019 13:09:36 GMT

←Older revision		Revision as of 13:09, 25 December 2019
Line 3:		Line 3:
	<StructureSection load='6pz9' size='340' side='right'caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>		<StructureSection load='6pz9' size='340' side='right'caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black-bellied_hamster Black-bellied hamster] and [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BJX:Repaglinide'>BJX</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BJX:Repaglinide'>BJX</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ABCC8, SUR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10034 Black-bellied hamster]), Kcnj11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz9 OCA], [http://pdbe.org/6pz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pz9 RCSB], [http://www.ebi.ac.uk/pdbsum/6pz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz9 OCA], [http://pdbe.org/6pz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pz9 RCSB], [http://www.ebi.ac.uk/pdbsum/6pz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz9 ProSAT]</span></td></tr>
	</table>		</table>
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 6pz9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6pz9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Potassium channel 3D structures\|Potassium channel 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Black-bellied hamster]]
		+	[[Category: Buffalo rat]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Martin, G M]]		[[Category: Martin, G M]]

OCA at 16:43, 14 August 2019

OCA — Wed, 14 Aug 2019 16:43:38 GMT

←Older revision		Revision as of 16:43, 14 August 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6pz9 is ~~ON HOLD~~	+	==Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide==
		+	<StructureSection load='6pz9' size='340' side='right'caption='[[6pz9]], [[Resolution\|resolution]] 3.65Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6pz9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PZ9 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BJX:Repaglinide'>BJX</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz9 OCA], [http://pdbe.org/6pz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pz9 RCSB], [http://www.ebi.ac.uk/pdbsum/6pz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz9 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ABCC8_CRICR ABCC8_CRICR]] Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive potassium channels and insulin release.[UniProtKB:Q09428] [[http://www.uniprot.org/uniprot/KCJ11_RAT KCJ11_RAT]] This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	ATP-sensitive potassium (KATP) channels composed of a pore-forming Kir6.2 potassium channel and a regulatory ABC transporter sulfonylurea receptor 1 (SUR1) regulate insulin secretion in pancreatic beta-cells to maintain glucose homeostasis. Mutations that impair channel folding or assembly prevent cell surface expression and cause congenital hyperinsulinism. Structurally diverse KATP inhibitors are known to act as pharmacochaperones to correct mutant channel expression, but the mechanism is unknown. Here, we compare cryoEM structures of a mammalian KATP channel bound to pharmacochaperones glibenclamide, repaglinide, and carbamazepine. We found all three drugs bind within a common pocket in SUR1. Further, we found the N-terminus of Kir6.2 inserted within the central cavity of the SUR1 ABC core, adjacent the drug binding pocket. The findings reveal a common mechanism by which diverse compounds stabilize the Kir6.2 N-terminus within SUR1's ABC core, allowing it to act as a firm 'handle' for the assembly of metastable mutant SUR1-Kir6.2 complexes.

-	~~Authors: Shyng, S.L~~., ~~Yoshioka~~, C., ~~Martin~~, ~~G.M.~~, ~~Sung~~, M.W.	+	Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM.,Martin GM, Sung MW, Yang Z, Innes LM, Kandasamy B, David LL, Yoshioka C, Shyng SL Elife. 2019 Jul 25;8. pii: 46417. doi: 10.7554/eLife.46417. PMID:31343405<ref>PMID:31343405</ref>

-	~~Description: SUR1~~-~~RPG~~-~~ATP state~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6pz9" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Martin, G M]]
		+	[[Category: Shyng, S L]]
		+	[[Category: Sung, M W]]
	[[Category: Yoshioka, C]]		[[Category: Yoshioka, C]]
-	[[Category: ~~Shyng, S.L~~]]	+	[[Category: Katp]]
-	[[Category: ~~Sung, M.W~~]]	+	[[Category: Membrane protein]]
-	[[Category: ~~Martin, G.M~~]]	+	[[Category: Rpg]]
		+	[[Category: Sur1]]

OCA: Protected "6pz9" [edit=sysop:move=sysop]

OCA — Wed, 07 Aug 2019 04:22:26 GMT

Protected "6pz9" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:22, 7 August 2019

OCA: New page: '''Unreleased structure''' The entry 6pz9 is ON HOLD Authors: Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W. Description: SUR1-RPG-ATP state Category: Unreleased Structures [[...

OCA — Wed, 07 Aug 2019 04:22:25 GMT

New page: '''Unreleased structure''' The entry 6pz9 is ON HOLD Authors: Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W. Description: SUR1-RPG-ATP state Category: Unreleased Structures [[...

New page

'''Unreleased structure'''

The entry 6pz9 is ON HOLD

Authors: Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W.

Description: SUR1-RPG-ATP state
[[Category: Unreleased Structures]]
[[Category: Yoshioka, C]]
[[Category: Shyng, S.L]]
[[Category: Sung, M.W]]
[[Category: Martin, G.M]]