6qgm - Revision history

OCA at 12:00, 24 January 2024

OCA — Wed, 24 Jan 2024 12:00:19 GMT

←Older revision		Revision as of 12:00, 24 January 2024
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	<StructureSection load='6qgm' size='340' side='right'caption='[[6qgm]], [[Resolution\|resolution]] 2.75Å' scene=''>		<StructureSection load='6qgm' size='340' side='right'caption='[[6qgm]], [[Resolution\|resolution]] 2.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qgm]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Cyanophage_syn10~~ Cyanophage ~~syn10~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6QGM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qgm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Cyanophage_Syn10 Cyanophage Syn10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QGM FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~CPUG_00131 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=536472 Cyanophage Syn10])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.75Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6qgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgm OCA], [~~http~~://pdbe.org/6qgm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6qgm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6qgm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgm OCA], [https://pdbe.org/6qgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qgm RCSB], [https://www.ebi.ac.uk/pdbsum/6qgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgm ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/M4SKV1_9CAUD M4SKV1_9CAUD]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Cyanophage ~~syn10~~]]	+	[[Category: Cyanophage Syn10]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gkotsi~~, D S~~]]	+	[[Category: Gkotsi DS]]
-	[[Category: Goss~~, R J.M~~]]	+	[[Category: Goss RJM]]
-	[[Category: Ludewig, H]]	+	[[Category: Ludewig H]]
-	[[Category: McLachlan~~, M M.W~~]]	+	[[Category: McLachlan MMW]]
-	[[Category: Naismith~~, J H~~]]	+	[[Category: Naismith JH]]
-	[[Category: Shanahan, S]]	+	[[Category: Shanahan S]]
-	[[Category: Sharma~~, S V~~]]	+	[[Category: Sharma SV]]
-	[[Category: Taylor~~, R J.K~~]]	+	[[Category: Taylor RJK]]
-	[[Category: Unsworth~~, W P]]~~	+	[[Category: Unsworth WP]]
-	~~[[Category: Fdh]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Iodinase]]~~	+
-	~~[[Category: Viral halogenase~~]]	+

OCA at 10:52, 4 December 2019

OCA — Wed, 04 Dec 2019 10:52:48 GMT

←Older revision		Revision as of 10:52, 4 December 2019
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	<StructureSection load='6qgm' size='340' side='right'caption='[[6qgm]], [[Resolution\|resolution]] 2.75Å' scene=''>		<StructureSection load='6qgm' size='340' side='right'caption='[[6qgm]], [[Resolution\|resolution]] 2.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qgm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qgm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Cyanophage_syn10 Cyanophage syn10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGM FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgm OCA], [http://pdbe.org/6qgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgm RCSB], [http://www.ebi.ac.uk/pdbsum/6qgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgm ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CPUG_00131 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536472 Cyanophage Syn10])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgm OCA], [http://pdbe.org/6qgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgm RCSB], [http://www.ebi.ac.uk/pdbsum/6qgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgm ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Cyanophage syn10]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Gkotsi, D S]]		[[Category: Gkotsi, D S]]

OCA at 09:08, 30 October 2019

OCA — Wed, 30 Oct 2019 09:08:15 GMT

←Older revision		Revision as of 09:08, 30 October 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6qgm is ~~ON HOLD until Paper~~ Publication	+	==VirX1 apo structure==
		+	<StructureSection load='6qgm' size='340' side='right'caption='[[6qgm]], [[Resolution\|resolution]] 2.75Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6qgm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGM FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgm OCA], [http://pdbe.org/6qgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgm RCSB], [http://www.ebi.ac.uk/pdbsum/6qgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgm ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Oceanic cyanobacteria are the most abundant oxygen-generating phototrophs on our planet and are therefore important to life. These organisms are infected by viruses called cyanophages, which have recently shown to encode metabolic genes that modulate host photosynthesis, phosphorus cycling and nucleotide metabolism. Herein we report the characterization of a wild-type flavin-dependent viral halogenase (VirX1) from a cyanophage. Notably, halogenases have been previously associated with secondary metabolism, tailoring natural products. Exploration of this viral halogenase reveals it capable of regioselective halogenation of a diverse range of substrates with a preference for forming aryl iodide species; this has potential implications for the metabolism of the infected host. Until recently, a flavin-dependent halogenase that is capable of iodination in vitro had not been reported. VirX1 is interesting from a biocatalytic perspective as it shows strikingly broad substrate flexibility and a clear preference for iodination, as illustrated by kinetic analysis. These factors together render it an attractive tool for synthesis.

-	~~Authors~~:	+	A marine viral halogenase that iodinates diverse substrates.,Gkotsi DS, Ludewig H, Sharma SV, Connolly JA, Dhaliwal J, Wang Y, Unsworth WP, Taylor RJK, McLachlan MMW, Shanahan S, Naismith JH, Goss RJM Nat Chem. 2019 Oct 14. pii: 10.1038/s41557-019-0349-z. doi:, 10.1038/s41557-019-0349-z. PMID:31611633<ref>PMID:31611633</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6qgm" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Gkotsi, D S]]
		+	[[Category: Goss, R J.M]]
		+	[[Category: Ludewig, H]]
		+	[[Category: McLachlan, M M.W]]
		+	[[Category: Naismith, J H]]
		+	[[Category: Shanahan, S]]
		+	[[Category: Sharma, S V]]
		+	[[Category: Taylor, R J.K]]
		+	[[Category: Unsworth, W P]]
		+	[[Category: Fdh]]
		+	[[Category: Hydrolase]]
		+	[[Category: Iodinase]]
		+	[[Category: Viral halogenase]]

OCA at 07:55, 13 February 2019

OCA — Wed, 13 Feb 2019 07:55:58 GMT

←Older revision		Revision as of 07:55, 13 February 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6qgm is ON HOLD	+	The entry 6qgm is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6qgm" [edit=sysop:move=sysop]

OCA — Wed, 30 Jan 2019 06:55:00 GMT

Protected "6qgm" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:55, 30 January 2019

OCA: New page: '''Unreleased structure''' The entry 6qgm is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 30 Jan 2019 06:54:58 GMT

New page: '''Unreleased structure''' The entry 6qgm is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6qgm is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]