6qkm - Revision history

OCA at 12:02, 24 January 2024

OCA — Wed, 24 Jan 2024 12:02:52 GMT

←Older revision		Revision as of 12:02, 24 January 2024
Line 3:		Line 3:
	<StructureSection load='6qkm' size='340' side='right'caption='[[6qkm]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='6qkm' size='340' side='right'caption='[[6qkm]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qkm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QKM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6QKM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qkm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidianus_ambivalens Acidianus ambivalens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QKM FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=FE:FE+(III)+ION'>FE</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.102Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=TSY:(2S)-2-AMINO-3-TRISULFANYLPROPANOIC+ACID'>TSY</scene~~></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=TSY:(2S)-2-AMINO-3-TRISULFANYLPROPANOIC+ACID'>TSY</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sulfur_oxygenase/reductase Sulfur oxygenase/reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.55 1.13.11.55] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qkm OCA], [https://pdbe.org/6qkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qkm RCSB], [https://www.ebi.ac.uk/pdbsum/6qkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qkm ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6qkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qkm OCA], [~~http~~://pdbe.org/6qkm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6qkm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6qkm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6qkm ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/SOR_ACIAM SOR_ACIAM]] Catalyzes the simultaneous oxidation and reduction of elemental sulfur in the presence of oxygen, with sulfite and hydrogen sulfide as products.<ref>PMID:15030315</ref>	+	[https://www.uniprot.org/uniprot/SOR_ACIAM SOR_ACIAM] Catalyzes the simultaneous oxidation and reduction of elemental sulfur in the presence of oxygen, with sulfite and hydrogen sulfide as products.<ref>PMID:15030315</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Numerous microorganisms oxidize sulfur for energy conservation and contribute to the global biogeochemical sulfur cycle. We have determined the 1.7 angstrom-resolution structure of the sulfur oxygenase reductase from the thermoacidophilic archaeon Acidianus ambivalens, which catalyzes an oxygen-dependent disproportionation of elemental sulfur. Twenty-four monomers form a large hollow sphere enclosing a positively charged nanocompartment. Apolar channels provide access for linear sulfur species. A cysteine persulfide and a low-potential mononuclear non-heme iron site ligated by a 2-His-1-carboxylate facial triad in a pocket of each subunit constitute the active sites, accessible from the inside of the sphere. The iron is likely the site of both sulfur oxidation and sulfur reduction.	+
-		+
-	~~X-ray Structure of a self-compartmentalizing sulfur cycle metalloenzyme.,Urich T, Gomes CM, Kletzin A, Frazao C Science. 2006 Feb 17;311(5763):996-1000. PMID:16484493<ref>PMID:16484493</ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 6qkm" style="background-color:#fffaf0;"></div~~>	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Acidianus ambivalens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Sulfur oxygenase/reductase]]~~	+	[[Category: Frazao C]]
-	[[Category: Frazao, C]]	+	[[Category: Klezin A]]
-	[[Category: Klezin, A]]	+	[[Category: Poell U]]
-	[[Category: Poell, U]]	+
-	~~[[Category: 2-his-1-carboxylate facial triad]]~~	+
-	~~[[Category: Biogeochemical sulfur cycle]]~~	+
-	~~[[Category: Cysteine persulphuration]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Sulfur oxygenase reductase~~]]	+

OCA at 06:28, 19 February 2020

OCA — Wed, 19 Feb 2020 06:28:39 GMT

←Older revision		Revision as of 06:28, 19 February 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6qkm is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==Diallyl trisulfide inhibited sulfur oxygenase reductase==
		+	<StructureSection load='6qkm' size='340' side='right'caption='[[6qkm]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6qkm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QKM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=TSY:(2S)-2-AMINO-3-TRISULFANYLPROPANOIC+ACID'>TSY</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sulfur_oxygenase/reductase Sulfur oxygenase/reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.55 1.13.11.55] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qkm OCA], [http://pdbe.org/6qkm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qkm RCSB], [http://www.ebi.ac.uk/pdbsum/6qkm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qkm ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SOR_ACIAM SOR_ACIAM]] Catalyzes the simultaneous oxidation and reduction of elemental sulfur in the presence of oxygen, with sulfite and hydrogen sulfide as products.<ref>PMID:15030315</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Numerous microorganisms oxidize sulfur for energy conservation and contribute to the global biogeochemical sulfur cycle. We have determined the 1.7 angstrom-resolution structure of the sulfur oxygenase reductase from the thermoacidophilic archaeon Acidianus ambivalens, which catalyzes an oxygen-dependent disproportionation of elemental sulfur. Twenty-four monomers form a large hollow sphere enclosing a positively charged nanocompartment. Apolar channels provide access for linear sulfur species. A cysteine persulfide and a low-potential mononuclear non-heme iron site ligated by a 2-His-1-carboxylate facial triad in a pocket of each subunit constitute the active sites, accessible from the inside of the sphere. The iron is likely the site of both sulfur oxidation and sulfur reduction.

-	~~Authors: Frazao, C~~., ~~Klezin~~, A., ~~Poell, U~~.	+	X-ray Structure of a self-compartmentalizing sulfur cycle metalloenzyme.,Urich T, Gomes CM, Kletzin A, Frazao C Science. 2006 Feb 17;311(5763):996-1000. PMID:16484493<ref>PMID:16484493</ref>

-	~~Description~~: ~~Diallyl trisulfide inhibited sulfur oxygenase reductase~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: ~~Klezin, A~~]]	+	<div class="pdbe-citations 6qkm" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Sulfur oxygenase/reductase]]
	[[Category: Frazao, C]]		[[Category: Frazao, C]]
		+	[[Category: Klezin, A]]
	[[Category: Poell, U]]		[[Category: Poell, U]]
		+	[[Category: 2-his-1-carboxylate facial triad]]
		+	[[Category: Biogeochemical sulfur cycle]]
		+	[[Category: Cysteine persulphuration]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Sulfur oxygenase reductase]]

OCA at 05:09, 27 March 2019

OCA — Wed, 27 Mar 2019 05:09:19 GMT

←Older revision		Revision as of 05:09, 27 March 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6qkm is ON HOLD	+	The entry 6qkm is ON HOLD until Paper Publication

	Authors: Frazao, C., Klezin, A., Poell, U.		Authors: Frazao, C., Klezin, A., Poell, U.

OCA at 13:52, 27 February 2019

OCA — Wed, 27 Feb 2019 13:52:58 GMT

←Older revision		Revision as of 13:52, 27 February 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6qkm is ON HOLD ~~until sometime in the future~~	+	The entry 6qkm is ON HOLD

	Authors: Frazao, C., Klezin, A., Poell, U.		Authors: Frazao, C., Klezin, A., Poell, U.

OCA: Protected "6qkm" [edit=sysop:move=sysop]

OCA — Wed, 13 Feb 2019 08:00:45 GMT

Protected "6qkm" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:00, 13 February 2019

OCA: New page: '''Unreleased structure''' The entry 6qkm is ON HOLD until sometime in the future Authors: Frazao, C., Klezin, A., Poell, U. Description: Diallyl trisulfide inhibited sulfur oxygenase ...

OCA — Wed, 13 Feb 2019 08:00:44 GMT

New page: '''Unreleased structure''' The entry 6qkm is ON HOLD until sometime in the future Authors: Frazao, C., Klezin, A., Poell, U. Description: Diallyl trisulfide inhibited sulfur oxygenase ...

New page

'''Unreleased structure'''

The entry 6qkm is ON HOLD until sometime in the future

Authors: Frazao, C., Klezin, A., Poell, U.

Description: Diallyl trisulfide inhibited sulfur oxygenase reductase
[[Category: Unreleased Structures]]
[[Category: Klezin, A]]
[[Category: Frazao, C]]
[[Category: Poell, U]]