6qs9 - Revision history

OCA at 12:07, 24 January 2024

OCA — Wed, 24 Jan 2024 12:07:29 GMT

←Older revision		Revision as of 12:07, 24 January 2024
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	<StructureSection load='6qs9' size='340' side='right'caption='[[6qs9]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='6qs9' size='340' side='right'caption='[[6qs9]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qs9]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bovin Bovin~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QS9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6QS9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qs9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QS9 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=CA:CALCIUM+ION'>CA</scene~~>, ~~<scene name='pdbligand=JGE:(R)-Ketoprofen'>JGE</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.802Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~ALB ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=9913 BOVIN]~~)</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=JGE:(R)-Ketoprofen'>JGE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qs9 OCA], [~~http~~://pdbe.org/6qs9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6qs9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6qs9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6qs9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qs9 OCA], [https://pdbe.org/6qs9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qs9 RCSB], [https://www.ebi.ac.uk/pdbsum/6qs9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qs9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.	+	[https://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6qs9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6qs9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Albumin 3D structures\|Albumin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bovin~~]]	+	[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Donini, S]]	+	[[Category: Donini S]]
-	[[Category: Parisini, E]]	+	[[Category: Parisini E]]
-	~~[[Category: Non-steroidal anti-inflammatory drug]]~~	+
-	~~[[Category: Plasma protein]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 13:11, 25 December 2019

OCA — Wed, 25 Dec 2019 13:11:56 GMT

←Older revision		Revision as of 13:11, 25 December 2019
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	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.		[[http://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A current challenge in materials science and biotechnology is to express a specific and controlled functionality on the large interfacial area of a nanostructured material to create smart biohybrid systems for targeted applications. Here, we report on a biohybrid system featuring poly(vinyl alcohol) as the supporting synthetic polymer and bovine serum albumin as the biofunctional element. The optimal processing conditions to produce these self-standing composite membranes are determined, and the composition and distribution of the bioactive agent within the polymeric matrices are analyzed. A post-processing cross-linking using glutaraldehyde enables this functional membrane to be used as a chemical filter in aqueous environments. By demonstrating that our mats can remove large amounts of ketoprofen from water, we show that the combination of a BSA-induced biofunctionality with a nanostructured fibrous material allows for the development of an efficient biohybrid filtering device for the large and widely used family of nonsteroidal anti-inflammatory drugs (NSAIDs). The crystal structure of the complex between BSA and ketoprofen is determined for the first time and confirms the interaction between the two species.
		+
		+	Biohybrid Electrospun Membrane for the Filtration of Ketoprofen Drug from Water.,Castagna R, Donini S, Colnago P, Serafini A, Parisini E, Bertarelli C ACS Omega. 2019 Aug 6;4(8):13270-13278. doi: 10.1021/acsomega.9b01442., eCollection 2019 Aug 20. PMID:31460455<ref>PMID:31460455</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6qs9" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:21, 10 October 2019

OCA — Thu, 10 Oct 2019 06:21:50 GMT

←Older revision		Revision as of 06:21, 10 October 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6qs9 is ~~ON HOLD until Paper Publication~~	+	==Bovine Serum Albumin in complex with Ketoprofen==
-		+	<StructureSection load='6qs9' size='340' side='right'caption='[[6qs9]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6qs9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QS9 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=JGE:(R)-Ketoprofen'>JGE</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qs9 OCA], [http://pdbe.org/6qs9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qs9 RCSB], [http://www.ebi.ac.uk/pdbsum/6qs9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qs9 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bovin]]
		+	[[Category: Large Structures]]
		+	[[Category: Donini, S]]
		+	[[Category: Parisini, E]]
		+	[[Category: Non-steroidal anti-inflammatory drug]]
		+	[[Category: Plasma protein]]
		+	[[Category: Transport protein]]

OCA: Protected "6qs9" [edit=sysop:move=sysop]

OCA — Wed, 27 Feb 2019 14:01:06 GMT

Protected "6qs9" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:01, 27 February 2019

OCA: New page: '''Unreleased structure''' The entry 6qs9 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Wed, 27 Feb 2019 14:01:05 GMT

New page: '''Unreleased structure''' The entry 6qs9 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6qs9 is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]