OCA at 05:56, 10 July 2019

OCA — Wed, 10 Jul 2019 05:56:22 GMT

←Older revision		Revision as of 05:56, 10 July 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6qtx is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of an Arabidopsis WD40 domain in complex with a flowering transcription factor homolog==
-		+	<StructureSection load='6qtx' size='340' side='right'caption='[[6qtx]], [[Resolution\|resolution]] 1.95Å' scene=''>
-	~~Authors~~: ~~Hothorn~~, M., ~~Lau~~, K.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6qtx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QTX FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure~~ of an ~~Arabidopsis WD40 domain~~ in ~~complex with~~ a ~~flowering~~ transcription ~~factor homolog~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RING-type_E3_ubiquitin_transferase RING-type E3 ubiquitin transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.27 2.3.2.27] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qtx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qtx OCA], [http://pdbe.org/6qtx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qtx RCSB], [http://www.ebi.ac.uk/pdbsum/6qtx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qtx ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/COP1_ARATH COP1_ARATH]] E3 ubiquitin-protein ligase that acts as a repressor of photomorphogenesis and as an activator of etiolation in darkness. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Represses photomorphogenesis in darkness by mediating ubiquitination and subsequent proteasomal degradation of light-induced transcription factors such as HY5, HYH and LAF1. Down-regulates MYB21, probably via ubiquitination process. Light stimuli abrogate the repression of photomorphogenesis, possibly due to its localization to the cytoplasm. Could play a role in switching between skotomorphogenetic and photomorphogenetic pathways.<ref>PMID:11967090</ref> <ref>PMID:12023303</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: RING-type E3 ubiquitin transferase]]
		+	[[Category: Hothorn, M]]
	[[Category: Lau, K]]		[[Category: Lau, K]]
-	[[Category: ~~Hothorn, M~~]]	+	[[Category: Complex]]
		+	[[Category: Plant protein]]

OCA: Protected "6qtx" [edit=sysop:move=sysop]

OCA — Wed, 06 Mar 2019 05:54:21 GMT

Protected "6qtx" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:54, 6 March 2019

OCA: New page: '''Unreleased structure''' The entry 6qtx is ON HOLD until Paper Publication Authors: Hothorn, M., Lau, K. Description: Crystal structure of an Arabidopsis WD40 domain in complex with ...

OCA — Wed, 06 Mar 2019 05:54:20 GMT

New page: '''Unreleased structure''' The entry 6qtx is ON HOLD until Paper Publication Authors: Hothorn, M., Lau, K. Description: Crystal structure of an Arabidopsis WD40 domain in complex with ...

New page

'''Unreleased structure'''

The entry 6qtx is ON HOLD until Paper Publication

Authors: Hothorn, M., Lau, K.

Description: Crystal structure of an Arabidopsis WD40 domain in complex with a flowering transcription factor homolog
[[Category: Unreleased Structures]]
[[Category: Lau, K]]
[[Category: Hothorn, M]]

6qtx - Revision history

OCA at 05:56, 10 July 2019

OCA: Protected "6qtx" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6qtx is ON HOLD until Paper Publication Authors: Hothorn, M., Lau, K. Description: Crystal structure of an Arabidopsis WD40 domain in complex with ...