6qua - Revision history

OCA at 12:08, 24 January 2024

OCA — Wed, 24 Jan 2024 12:08:55 GMT

←Older revision		Revision as of 12:08, 24 January 2024
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	<StructureSection load='6qua' size='340' side='right'caption='[[6qua]], [[Resolution\|resolution]] 2.68Å' scene=''>		<StructureSection load='6qua' size='340' side='right'caption='[[6qua]], [[Resolution\|resolution]] 2.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qua]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Halsa Halsa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QUA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6QUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qua]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum_NRC-1 Halobacterium salinarum NRC-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QUA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=MN:MANGANESE+(II)+ION'>MN</scene~~>, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.681Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~VNG_0258H ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=64091 HALSA])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6qua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qua OCA], [~~http~~://pdbe.org/6qua PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6qua RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6qua PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6qua ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qua OCA], [https://pdbe.org/6qua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qua RCSB], [https://www.ebi.ac.uk/pdbsum/6qua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qua ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9HSF4_HALSA Q9HSF4_HALSA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Halsa~~]]	+	[[Category: Halobacterium salinarum NRC-1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kutnowski, N]]	+	[[Category: Kutnowski N]]
-	[[Category: Shaanan, B]]	+	[[Category: Shaanan B]]
-	~~[[Category: Dna binding protein]]~~	+
-	~~[[Category: Halophile]]~~	+
-	~~[[Category: High salt medium]]~~	+
-	~~[[Category: Protein-dna interaction]]~~	+
-	~~[[Category: Rosr]]~~	+
-	~~[[Category: Whth dna binding protein~~]]	+

OCA at 08:43, 24 July 2019

OCA — Wed, 24 Jul 2019 08:43:47 GMT

←Older revision		Revision as of 08:43, 24 July 2019
Line 3:		Line 3:
	<StructureSection load='6qua' size='340' side='right'caption='[[6qua]], [[Resolution\|resolution]] 2.68Å' scene=''>		<StructureSection load='6qua' size='340' side='right'caption='[[6qua]], [[Resolution\|resolution]] 2.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qua]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qua]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Halsa Halsa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QUA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VNG_0258H ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=64091 HALSA])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qua OCA], [http://pdbe.org/6qua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qua RCSB], [http://www.ebi.ac.uk/pdbsum/6qua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qua ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qua OCA], [http://pdbe.org/6qua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qua RCSB], [http://www.ebi.ac.uk/pdbsum/6qua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qua ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Interactions between proteins and DNA are crucial for all biological systems. Many studies have shown the dependence of protein-DNA interactions on the surrounding salt concentration. How these interactions are maintained in the hypersaline environments that halophiles inhabit remains puzzling. Towards solving this enigma, we identified the DNA motif recognized by the Halobactrium salinarum ROS-dependent transcription factor (hsRosR), determined the structure of several hsRosR-DNA complexes and investigated the DNA-binding process under extreme high-salt conditions. The picture that emerges from this work contributes to our understanding of the principles underlying the interplay between electrostatic interactions and salt-mediated protein-DNA interactions in an ionic environment characterized by molar salt concentrations.
		+
		+	Specificity of protein-DNA interactions in hypersaline environment: structural studies on complexes of Halobacterium salinarum oxidative stress-dependent protein hsRosR.,Kutnowski N, Shmulevich F, Davidov G, Shahar A, Bar-Zvi D, Eichler J, Zarivach R, Shaanan B Nucleic Acids Res. 2019 Jul 16. pii: 5532612. doi: 10.1093/nar/gkz604. PMID:31310308<ref>PMID:31310308</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6qua" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Halsa]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Kutnowski, N]]		[[Category: Kutnowski, N]]

OCA at 05:56, 10 July 2019

OCA — Wed, 10 Jul 2019 05:56:43 GMT

←Older revision		Revision as of 05:56, 10 July 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6qua is ON HOLD until Paper Publication~~	+	==The complex structure of hsRosR-SG (vng0258/RosR-SG)==
-		+	<StructureSection load='6qua' size='340' side='right'caption='[[6qua]], [[Resolution\|resolution]] 2.68Å' scene=''>
-	~~Authors: Shaanan, B., Kutnowski, N.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6qua]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QUA FirstGlance]. <br>
-	~~Description:~~ The complex structure of hsRosR-SG (vng0258/RosR-SG)	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qua OCA], [http://pdbe.org/6qua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qua RCSB], [http://www.ebi.ac.uk/pdbsum/6qua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qua ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Kutnowski, N]]		[[Category: Kutnowski, N]]
	[[Category: Shaanan, B]]		[[Category: Shaanan, B]]
		+	[[Category: Dna binding protein]]
		+	[[Category: Halophile]]
		+	[[Category: High salt medium]]
		+	[[Category: Protein-dna interaction]]
		+	[[Category: Rosr]]
		+	[[Category: Whth dna binding protein]]

OCA: Protected "6qua" [edit=sysop:move=sysop]

OCA — Wed, 06 Mar 2019 05:55:59 GMT

Protected "6qua" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:55, 6 March 2019

OCA: New page: '''Unreleased structure''' The entry 6qua is ON HOLD until Paper Publication Authors: Shaanan, B., Kutnowski, N. Description: The complex structure of hsRosR-SG (vng0258/RosR-SG) [[Cat...

OCA — Wed, 06 Mar 2019 05:55:57 GMT

New page: '''Unreleased structure''' The entry 6qua is ON HOLD until Paper Publication Authors: Shaanan, B., Kutnowski, N. Description: The complex structure of hsRosR-SG (vng0258/RosR-SG) [[Cat...

New page

'''Unreleased structure'''

The entry 6qua is ON HOLD until Paper Publication

Authors: Shaanan, B., Kutnowski, N.

Description: The complex structure of hsRosR-SG (vng0258/RosR-SG)
[[Category: Unreleased Structures]]
[[Category: Kutnowski, N]]
[[Category: Shaanan, B]]