6qwr - Revision history

OCA at 11:00, 14 June 2023

OCA — Wed, 14 Jun 2023 11:00:56 GMT

←Older revision		Revision as of 11:00, 14 June 2023
Line 1:		Line 1:

	==Solid-state NMR structure of outer membrane protein AlkL in DMPC lipid bilayers==		==Solid-state NMR structure of outer membrane protein AlkL in DMPC lipid bilayers==
-	<StructureSection load='6qwr' size='340' side='right'caption='[[6qwr~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='6qwr' size='340' side='right'caption='[[6qwr]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qwr]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_17440_[[pseudomonas_pseudoalcaligenes]] Atcc 17440 [[pseudomonas pseudoalcaligenes]]~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6QWR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qwr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_oleovorans Pseudomonas oleovorans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QWR FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6qam\|6qam]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwr OCA], [https://pdbe.org/6qwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qwr RCSB], [https://www.ebi.ac.uk/pdbsum/6qwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwr ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alkL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=301 ATCC 17440 [[Pseudomonas pseudoalcaligenes]]])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6qwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwr OCA], [~~http~~://pdbe.org/6qwr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6qwr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6qwr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwr ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ALKL_PSEOL ALKL_PSEOL]] Could be involved in the transport of substrates.	+	[https://www.uniprot.org/uniprot/ALKL_PSEOL ALKL_PSEOL] Could be involved in the transport of substrates.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Andreas, L B~~]]	+	[[Category: Pseudomonas oleovorans]]
-	[[Category: ~~Pintacuda, G~~]]	+	[[Category: Andreas LB]]
-	[[Category: ~~Schubeis, T~~]]	+	[[Category: Pintacuda G]]
-	[[Category: ~~Beta barrel]]~~	+	[[Category: Schubeis T]]
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Outer membrane protein]]~~	+
-	~~[[Category: Porin]]~~	+
-	~~[[Category: Transporter~~]]	+

OCA at 07:03, 2 September 2020

OCA — Wed, 02 Sep 2020 07:03:30 GMT

←Older revision		Revision as of 07:03, 2 September 2020
Line 10:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ALKL_PSEOL ALKL_PSEOL]] Could be involved in the transport of substrates.		[[http://www.uniprot.org/uniprot/ALKL_PSEOL ALKL_PSEOL]] Could be involved in the transport of substrates.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The protein AlkL is known to increase permeability of the outer membrane of bacteria for hydrophobic molecules, yet the mechanism of transport has not been determined. Differing crystal and NMR structures of homologous proteins resulted in a controversy regarding the degree of structure and the role of long extracellular loops. Here we solve this controversy by determining the de novo NMR structure in near-native lipid bilayers, and by accessing structural dynamics relevant to hydrophobic substrate permeation through molecular-dynamics simulations and by characteristic NMR relaxation parameters. Dynamic lateral exit sites large enough to accommodate substrates such as carvone or octane occur through restructuring of a barrel extension formed by the extracellular loops.
		+
		+	A beta-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL.,Schubeis T, Le Marchand T, Daday C, Kopec W, Tekwani Movellan K, Stanek J, Schwarzer TS, Castiglione K, de Groot BL, Pintacuda G, Andreas LB Proc Natl Acad Sci U S A. 2020 Aug 19. pii: 2002598117. doi:, 10.1073/pnas.2002598117. PMID:32817429<ref>PMID:32817429</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6qwr" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:28, 26 August 2020

OCA — Wed, 26 Aug 2020 11:28:54 GMT

←Older revision		Revision as of 11:28, 26 August 2020
Line 3:		Line 3:
	<StructureSection load='6qwr' size='340' side='right'caption='[[6qwr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='6qwr' size='340' side='right'caption='[[6qwr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6qwr]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWR OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6QWR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6qwr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_17440_[[pseudomonas_pseudoalcaligenes]] Atcc 17440 [[pseudomonas pseudoalcaligenes]]]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6QWR FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6qam\|6qam]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6qam\|6qam]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6qwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwr OCA], [http://pdbe.org/6qwr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qwr RCSB], [http://www.ebi.ac.uk/pdbsum/6qwr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwr ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alkL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=301 ATCC 17440 [[Pseudomonas pseudoalcaligenes]]])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6qwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwr OCA], [http://pdbe.org/6qwr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qwr RCSB], [http://www.ebi.ac.uk/pdbsum/6qwr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 09:49, 18 March 2020

OCA — Wed, 18 Mar 2020 09:49:12 GMT

←Older revision		Revision as of 09:49, 18 March 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6qwr is ~~ON HOLD~~	+	==Solid-state NMR structure of outer membrane protein AlkL in DMPC lipid bilayers==
-		+	<StructureSection load='6qwr' size='340' side='right'caption='[[6qwr]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-	~~Authors~~: ~~Schubeis~~, T., ~~Andreas~~, L.B., ~~Pintacuda~~, G.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6qwr]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QWR FirstGlance]. <br>
-	~~Description~~: ~~Solid-state NMR structure of outer membrane protein AlkL~~ in ~~DMPC lipid bilayers~~	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6qam\|6qam]]</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwr OCA], [http://pdbe.org/6qwr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qwr RCSB], [http://www.ebi.ac.uk/pdbsum/6qwr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwr ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ALKL_PSEOL ALKL_PSEOL]] Could be involved in the transport of substrates.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Andreas, L B]]
		+	[[Category: Pintacuda, G]]
	[[Category: Schubeis, T]]		[[Category: Schubeis, T]]
-	[[Category: ~~Andreas, L.B~~]]	+	[[Category: Beta barrel]]
-	[[Category: ~~Pintacuda, G~~]]	+	[[Category: Membrane protein]]
		+	[[Category: Outer membrane protein]]
		+	[[Category: Porin]]
		+	[[Category: Transporter]]

OCA: Protected "6qwr" [edit=sysop:move=sysop]

OCA — Wed, 13 Mar 2019 10:28:53 GMT

Protected "6qwr" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:28, 13 March 2019

OCA: New page: '''Unreleased structure''' The entry 6qwr is ON HOLD Authors: Schubeis, T., Andreas, L.B., Pintacuda, G. Description: Solid-state NMR structure of outer membrane protein AlkL in DMPC l...

OCA — Wed, 13 Mar 2019 10:28:52 GMT

New page: '''Unreleased structure''' The entry 6qwr is ON HOLD Authors: Schubeis, T., Andreas, L.B., Pintacuda, G. Description: Solid-state NMR structure of outer membrane protein AlkL in DMPC l...

New page

'''Unreleased structure'''

The entry 6qwr is ON HOLD

Authors: Schubeis, T., Andreas, L.B., Pintacuda, G.

Description: Solid-state NMR structure of outer membrane protein AlkL in DMPC lipid bilayers
[[Category: Unreleased Structures]]
[[Category: Schubeis, T]]
[[Category: Andreas, L.B]]
[[Category: Pintacuda, G]]