6r5z - Revision history

OCA at 12:15, 24 January 2024

OCA — Wed, 24 Jan 2024 12:15:55 GMT

←Older revision		Revision as of 12:15, 24 January 2024
Line 3:		Line 3:
	<StructureSection load='6r5z' size='340' side='right'caption='[[6r5z]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='6r5z' size='340' side='right'caption='[[6r5z]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6r5z]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R5Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6R5Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6r5z]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R5Z FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6r5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r5z OCA], [~~http~~://pdbe.org/6r5z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6r5z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6r5z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6r5z ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r5z OCA], [https://pdbe.org/6r5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r5z RCSB], [https://www.ebi.ac.uk/pdbsum/6r5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r5z ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B2J0I0_NOSP7 B2J0I0_NOSP7]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Hartmann, M D~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Lupas, A N~~]]	+	[[Category: Hartmann MD]]
-	[[Category: ~~Martin, J~~]]	+	[[Category: Lupas AN]]
-	[[Category: ~~Fragment amplification]]~~	+	[[Category: Martin J]]
-	~~[[Category: Protein design]]~~	+
-	~~[[Category: Protein evolution]]~~	+
-	~~[[Category: Repeat protein]]~~	+
-	~~[[Category: Unknown function]]~~	+
-	~~[[Category: Wd40~~]]	+

OCA at 11:11, 13 November 2019

OCA — Wed, 13 Nov 2019 11:11:36 GMT

←Older revision		Revision as of 11:11, 13 November 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6r5z is ~~ON HOLD~~	+	==9-bladed beta-propeller formed by three 3-bladed fragments==
		+	<StructureSection load='6r5z' size='340' side='right'caption='[[6r5z]], [[Resolution\|resolution]] 1.75Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6r5z]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R5Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R5Z FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r5z OCA], [http://pdbe.org/6r5z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r5z RCSB], [http://www.ebi.ac.uk/pdbsum/6r5z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r5z ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	beta-Propellers arise through the amplification of a supersecondary structure element called a blade. This process produces toroids of between four and twelve repeats, which are almost always arranged sequentially in a single polypeptide chain. We found that new propellers evolve continuously by amplification from single blades. We therefore investigated whether such nascent propellers can fold as homo-oligomers before they have been fully amplified within a single chain. One- to six-bladed building blocks derived from two seven-bladed WD40 propellers yielded stable homo-oligomers with six to nine blades, depending on the size of the building block. High-resolution structures for tetramers of two blades, trimers of three blades, and dimers of four and five blades, respectively, show structurally diverse propellers and include a novel fold, highlighting the inherent flexibility of the WD40 blade. Our data support the hypothesis that subdomain-sized fragments can provide structural versatility in the evolution of new proteins.

-	~~Authors~~:	+	Structural diversity of oligomeric beta-propellers with different numbers of identical blades.,Afanasieva E, Chaudhuri I, Martin J, Hertle E, Ursinus A, Alva V, Hartmann MD, Lupas AN Elife. 2019 Oct 15;8. pii: 49853. doi: 10.7554/eLife.49853. PMID:31613220<ref>PMID:31613220</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6r5z" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Hartmann, M D]]
		+	[[Category: Lupas, A N]]
		+	[[Category: Martin, J]]
		+	[[Category: Fragment amplification]]
		+	[[Category: Protein design]]
		+	[[Category: Protein evolution]]
		+	[[Category: Repeat protein]]
		+	[[Category: Unknown function]]
		+	[[Category: Wd40]]

OCA: Protected "6r5z" [edit=sysop:move=sysop]

OCA — Wed, 03 Apr 2019 05:00:47 GMT

Protected "6r5z" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:00, 3 April 2019

OCA: New page: '''Unreleased structure''' The entry 6r5z is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 03 Apr 2019 05:00:45 GMT

New page: '''Unreleased structure''' The entry 6r5z is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6r5z is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]