6r9l - Revision history

OCA at 11:01, 14 June 2023

OCA — Wed, 14 Jun 2023 11:01:28 GMT

←Older revision		Revision as of 11:01, 14 June 2023
Line 1:		Line 1:

	==A quadruplex hybrid structure with lpp loop orientation and 5 syn residues==		==A quadruplex hybrid structure with lpp loop orientation and 5 syn residues==
-	<StructureSection load='6r9l' size='340' side='right'caption='[[6r9l~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='6r9l' size='340' side='right'caption='[[6r9l]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6r9l]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R9L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6r9l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R9L FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGM:8-BROMO-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>BGM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGM:8-BROMO-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>BGM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r9l OCA], [https://pdbe.org/6r9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r9l RCSB], [https://www.ebi.ac.uk/pdbsum/6r9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r9l ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r9l OCA], [https://pdbe.org/6r9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r9l RCSB], [https://www.ebi.ac.uk/pdbsum/6r9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r9l ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Karg, B]]	+	[[Category: Karg B]]
-	[[Category: Weisz, K]]	+	[[Category: Weisz K]]
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Duplex moiety]]~~	+
-	~~[[Category: G-quadruplex]]~~	+
-	~~[[Category: Hybrid structure~~]]	+

OCA at 07:41, 25 June 2021

OCA — Fri, 25 Jun 2021 07:41:21 GMT

←Older revision		Revision as of 07:41, 25 June 2021
Line 3:		Line 3:
	<StructureSection load='6r9l' size='340' side='right'caption='[[6r9l]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='6r9l' size='340' side='right'caption='[[6r9l]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6r9l]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R9L OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6R9L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6r9l]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R9L FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGM:8-BROMO-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>BGM</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGM:8-BROMO-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>BGM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6r9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r9l OCA], [~~http~~://pdbe.org/6r9l PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6r9l RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6r9l PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6r9l ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r9l OCA], [https://pdbe.org/6r9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r9l RCSB], [https://www.ebi.ac.uk/pdbsum/6r9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r9l ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:03, 3 July 2019

OCA — Wed, 03 Jul 2019 06:03:46 GMT

←Older revision		Revision as of 06:03, 3 July 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6r9l is ~~ON HOLD~~	+	==A quadruplex hybrid structure with lpp loop orientation and 5 syn residues==
		+	<StructureSection load='6r9l' size='340' side='right'caption='[[6r9l]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6r9l]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R9L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R9L FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGM:8-BROMO-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>BGM</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r9l OCA], [http://pdbe.org/6r9l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r9l RCSB], [http://www.ebi.ac.uk/pdbsum/6r9l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r9l ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The oligomer d(GCGTG3 TCAG3 TG3 TG3 ACGC) with short complementary flanking sequences at the 5'- and 3'-ends was shown to fold into three different DNA G-quadruplex species. In contrast, a corresponding oligomer that lacks base complementarity between the two overhang sequences folds into a single parallel G-quadruplex. The three coexisting quadruplex structures were unambiguously identified and structurally characterized through detailed spectral comparisons with well-defined G-quadruplexes formed upon the deliberate incorporation of syn-favoring 8-bromoguanosine analogues into specific positions of the G-core. Two (3+1) hybrid structures coexist with the parallel fold and feature a novel lateral-propeller-propeller loop architecture that has not yet been confirmed experimentally. Both hybrid quadruplexes adopt the same topology and only differ in their pattern of anti-->syn transitions and tetrad stackings.

-	~~Authors: Karg~~, B., ~~Weisz~~, K.	+	Duplex-Guided Refolding into Novel G-Quadruplex (3+1) Hybrid Conformations.,Karg B, Mohr S, Weisz K Angew Chem Int Ed Engl. 2019 May 28. doi: 10.1002/anie.201905372. PMID:31134741<ref>PMID:31134741</ref>

-	~~Description~~: ~~A quadruplex hybrid structure with lpp loop orientation and 5 syn residues~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6r9l" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Karg, B]]		[[Category: Karg, B]]
	[[Category: Weisz, K]]		[[Category: Weisz, K]]
		+	[[Category: Dna]]
		+	[[Category: Duplex moiety]]
		+	[[Category: G-quadruplex]]
		+	[[Category: Hybrid structure]]

OCA: Protected "6r9l" [edit=sysop:move=sysop]

OCA — Wed, 10 Apr 2019 05:46:56 GMT

Protected "6r9l" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:46, 10 April 2019

OCA: New page: '''Unreleased structure''' The entry 6r9l is ON HOLD Authors: Karg, B., Weisz, K. Description: A quadruplex hybrid structure with lpp loop orientation and 5 syn residues [[Category: Un...

OCA — Wed, 10 Apr 2019 05:46:54 GMT

New page: '''Unreleased structure''' The entry 6r9l is ON HOLD Authors: Karg, B., Weisz, K. Description: A quadruplex hybrid structure with lpp loop orientation and 5 syn residues [[Category: Un...

New page

'''Unreleased structure'''

The entry 6r9l is ON HOLD

Authors: Karg, B., Weisz, K.

Description: A quadruplex hybrid structure with lpp loop orientation and 5 syn residues
[[Category: Unreleased Structures]]
[[Category: Karg, B]]
[[Category: Weisz, K]]