6rfg - Revision history

OCA at 13:12, 25 December 2019

OCA — Wed, 25 Dec 2019 13:12:18 GMT

←Older revision		Revision as of 13:12, 25 December 2019
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	<StructureSection load='6rfg' size='340' side='right'caption='[[6rfg]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='6rfg' size='340' side='right'caption='[[6rfg]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rfg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RFG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RFG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rfg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RFG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RFG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rfg OCA], [http://pdbe.org/6rfg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rfg RCSB], [http://www.ebi.ac.uk/pdbsum/6rfg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rfg ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E11L, VACV_BRZ_SERRO2_065, 51.1rMVA_076, List063, LIVPclone14_074, m8081L, mO081L, VAC_DPP10_078, VAC_DPP11_078, VAC_DPP12_078, VAC_DPP13_078, VAC_DPP15_078, VAC_DPP16_078, VAC_DPP17_078, VAC_DPP19_078, VAC_DPP20_078, VAC_DPP21_078, VAC_DPP25_078, VAC_DPP9_078, VAC_IHDW1_068, VAC_TKT3_056, VAC_TKT4_056, VAC_TP3_071, VAC_TP5_071, VACAC2_078, VACCL3_078, VACV-DUKE-075, VACV_063, VACV_CTGV_CM01_066, VACV_IOC_B141_092, VACV_IOC_B388_092, VACV_TT10_083, VACV_TT11_083, VACV_TT12_083, VACV_TT8_083, VACV_TT9_083 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rfg OCA], [http://pdbe.org/6rfg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rfg RCSB], [http://www.ebi.ac.uk/pdbsum/6rfg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rfg ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Poxviruses encode a multisubunit DNA-dependent RNA polymerase (vRNAP) that carries out viral gene expression in the host cytoplasm. We report cryo-EM structures of core and complete vRNAP enzymes from Vaccinia virus at 2.8 A resolution. The vRNAP core enzyme resembles eukaryotic RNA polymerase II (Pol II) but also reveals many virus-specific features, including the transcription factor Rap94. The complete enzyme additionally contains the transcription factor VETF, the mRNA processing factors VTF/CE and NPH-I, the viral core protein E11, and host tRNA(Gln). This complex can carry out the entire early transcription cycle. The structures show that Rap94 partially resembles the Pol II initiation factor TFIIB, that the vRNAP subunit Rpo30 resembles the Pol II elongation factor TFIIS, and that NPH-I resembles chromatin remodeling enzymes. Together with the accompanying paper (Hillen et al., 2019), these results provide the basis for unraveling the mechanisms of poxvirus transcription and RNA processing.
		+
		+	Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.,Grimm C, Hillen HS, Bedenk K, Bartuli J, Neyer S, Zhang Q, Huttenhofer A, Erlacher M, Dienemann C, Schlosser A, Urlaub H, Bottcher B, Szalay AA, Cramer P, Fischer U Cell. 2019 Dec 12;179(7):1537-1550.e19. doi: 10.1016/j.cell.2019.11.024. PMID:31835032<ref>PMID:31835032</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6rfg" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Vaccinia virus]]
	[[Category: Fischer, U]]		[[Category: Fischer, U]]
	[[Category: Grimm, C]]		[[Category: Grimm, C]]

OCA at 15:14, 11 December 2019

OCA — Wed, 11 Dec 2019 15:14:49 GMT

←Older revision		Revision as of 15:14, 11 December 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6rfg ~~is ON HOLD until Paper Publication~~	+	==Structure of the Vaccinia core protein E11==
-		+	<StructureSection load='6rfg' size='340' side='right'caption='[[6rfg]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~Authors~~: ~~Grimm~~, C., ~~Fischer~~, U.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6rfg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RFG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RFG FirstGlance]. <br>
-	~~Description: Structure of the Vaccinia core protein E11~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rfg OCA], [http://pdbe.org/6rfg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rfg RCSB], [http://www.ebi.ac.uk/pdbsum/6rfg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rfg ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Fischer, U]]
	[[Category: Grimm, C]]		[[Category: Grimm, C]]
-	[[Category: ~~Fischer, U~~]]	+	[[Category: Core protein]]
		+	[[Category: E11]]
		+	[[Category: E11l]]
		+	[[Category: Rna polymerase complex]]
		+	[[Category: Vaccinia]]
		+	[[Category: Viral protein]]

OCA at 09:21, 13 November 2019

OCA — Wed, 13 Nov 2019 09:21:45 GMT

←Older revision		Revision as of 09:21, 13 November 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6rfg is ON HOLD	+	The entry 6rfg is ON HOLD until Paper Publication

	Authors: Grimm, C., Fischer, U.		Authors: Grimm, C., Fischer, U.

OCA: Protected "6rfg" [edit=sysop:move=sysop]

OCA — Wed, 24 Apr 2019 05:14:51 GMT

Protected "6rfg" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:14, 24 April 2019

OCA: New page: '''Unreleased structure''' The entry 6rfg is ON HOLD Authors: Grimm, C., Fischer, U. Description: Structure of the Vaccinia core protein E11 Category: Unreleased Structures [[Categ...

OCA — Wed, 24 Apr 2019 05:14:49 GMT

New page: '''Unreleased structure''' The entry 6rfg is ON HOLD Authors: Grimm, C., Fischer, U. Description: Structure of the Vaccinia core protein E11 Category: Unreleased Structures [[Categ...

New page

'''Unreleased structure'''

The entry 6rfg is ON HOLD

Authors: Grimm, C., Fischer, U.

Description: Structure of the Vaccinia core protein E11
[[Category: Unreleased Structures]]
[[Category: Grimm, C]]
[[Category: Fischer, U]]