6rj8 - Revision history

OCA at 12:21, 24 January 2024

OCA — Wed, 24 Jan 2024 12:21:34 GMT

←Older revision		Revision as of 12:21, 24 January 2024
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	<StructureSection load='6rj8' size='340' side='right'caption='[[6rj8]], [[Resolution\|resolution]] 1.42Å' scene=''>		<StructureSection load='6rj8' size='340' side='right'caption='[[6rj8]], [[Resolution\|resolution]] 1.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rj8]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Tabernanthe_iboga Tabernanthe iboga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJ8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6RJ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rj8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tabernanthe_iboga Tabernanthe iboga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RJ8 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=EDO:1,2~~-~~ETHANEDIOL'>EDO</scene>~~, ~~<scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.42Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~corS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=141617 Tabernanthe iboga])</td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/2-hydroxyisoflavanone_dehydratase 2-hydroxyisoflavanone dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.105 4.2.1.105]~~ </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rj8 OCA], [https://pdbe.org/6rj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rj8 RCSB], [https://www.ebi.ac.uk/pdbsum/6rj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rj8 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6rj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rj8 OCA], [~~http~~://pdbe.org/6rj8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6rj8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6rj8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6rj8 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A5B8X6B5_TABIB A0A5B8X6B5_TABIB]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: 2-hydroxyisoflavanone dehydratase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Tabernanthe iboga]]		[[Category: Tabernanthe iboga]]
-	[[Category: Bussey, K]]	+	[[Category: Bussey K]]
-	[[Category: Caputi, L]]	+	[[Category: Caputi L]]
-	~~[[Category: Connor, S E.O~~]]	+	[[Category: Farrow SC]]
-	[[Category: Farrow~~, S C~~]]	+	[[Category: Kamileen MO]]
-	[[Category: Kamileen~~, M O~~]]	+	[[Category: Lawson DM]]
-	[[Category: Lawson~~, D M~~]]	+	[[Category: Mundy J]]
-	[[Category: Mundy, J]]	+	[[Category: O'Connor SE]]
-	[[Category: ~~Stevenson, C E.M~~]]	+	[[Category: Stevenson CEM]]
-	[[Category: ~~Alkaloid]]~~	+
-	~~[[Category: Alpha/beta hydrolase fold]]~~	+
-	~~[[Category: Biosynthesis]]~~	+
-	~~[[Category: Coronaridine]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Iboga]]~~	+
-	~~[[Category: Natural product~~]]	+

OCA at 09:40, 1 April 2020

OCA — Wed, 01 Apr 2020 09:40:17 GMT

←Older revision		Revision as of 09:40, 1 April 2020
Line 3:		Line 3:
	<StructureSection load='6rj8' size='340' side='right'caption='[[6rj8]], [[Resolution\|resolution]] 1.42Å' scene=''>		<StructureSection load='6rj8' size='340' side='right'caption='[[6rj8]], [[Resolution\|resolution]] 1.42Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rj8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rj8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tabernanthe_iboga Tabernanthe iboga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJ8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">corS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=141617 Tabernanthe iboga])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-hydroxyisoflavanone_dehydratase 2-hydroxyisoflavanone dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.105 4.2.1.105] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-hydroxyisoflavanone_dehydratase 2-hydroxyisoflavanone dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.105 4.2.1.105] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rj8 OCA], [http://pdbe.org/6rj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rj8 RCSB], [http://www.ebi.ac.uk/pdbsum/6rj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rj8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rj8 OCA], [http://pdbe.org/6rj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rj8 RCSB], [http://www.ebi.ac.uk/pdbsum/6rj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rj8 ProSAT]</span></td></tr>
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	[[Category: 2-hydroxyisoflavanone dehydratase]]		[[Category: 2-hydroxyisoflavanone dehydratase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Tabernanthe iboga]]
	[[Category: Bussey, K]]		[[Category: Bussey, K]]
	[[Category: Caputi, L]]		[[Category: Caputi, L]]

OCA at 06:47, 4 March 2020

OCA — Wed, 04 Mar 2020 06:47:54 GMT

←Older revision		Revision as of 06:47, 4 March 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6rj8 is ~~ON HOLD until Paper~~ Publication	+	==Structure of the alpha-beta hydrolase CorS from Tabernathe iboga==
		+	<StructureSection load='6rj8' size='340' side='right'caption='[[6rj8]], [[Resolution\|resolution]] 1.42Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6rj8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJ8 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-hydroxyisoflavanone_dehydratase 2-hydroxyisoflavanone dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.105 4.2.1.105] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rj8 OCA], [http://pdbe.org/6rj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rj8 RCSB], [http://www.ebi.ac.uk/pdbsum/6rj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rj8 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cycloaddition reactions generate chemical complexity in a single step. Here we report the crystal structures of three homologous plant-derived cyclases involved in the biosynthesis of iboga and aspidosperma alkaloids. These enzymes act on the same substrate, named angryline, to generate three distinct scaffolds. Mutational analysis reveals how these highly similar enzymes control regio- and stereo-selectivity.

-	~~Authors~~:	+	Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids.,Caputi L, Franke J, Bussey K, Farrow SC, Vieira IJC, Stevenson CEM, Lawson DM, O'Connor SE Nat Chem Biol. 2020 Feb 17. pii: 10.1038/s41589-019-0460-x. doi:, 10.1038/s41589-019-0460-x. PMID:32066966<ref>PMID:32066966</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6rj8" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: 2-hydroxyisoflavanone dehydratase]]
		+	[[Category: Large Structures]]
		+	[[Category: Bussey, K]]
		+	[[Category: Caputi, L]]
		+	[[Category: Connor, S E.O]]
		+	[[Category: Farrow, S C]]
		+	[[Category: Kamileen, M O]]
		+	[[Category: Lawson, D M]]
		+	[[Category: Mundy, J]]
		+	[[Category: Stevenson, C E.M]]
		+	[[Category: Alkaloid]]
		+	[[Category: Alpha/beta hydrolase fold]]
		+	[[Category: Biosynthesis]]
		+	[[Category: Coronaridine]]
		+	[[Category: Hydrolase]]
		+	[[Category: Iboga]]
		+	[[Category: Natural product]]

OCA: Protected "6rj8" [edit=sysop:move=sysop]

OCA — Wed, 01 May 2019 07:27:18 GMT

Protected "6rj8" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:27, 1 May 2019

OCA: New page: '''Unreleased structure''' The entry 6rj8 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Wed, 01 May 2019 07:27:16 GMT

New page: '''Unreleased structure''' The entry 6rj8 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6rj8 is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]