6rji - Revision history

OCA at 12:21, 24 January 2024

OCA — Wed, 24 Jan 2024 12:21:38 GMT

←Older revision		Revision as of 12:21, 24 January 2024
Line 3:		Line 3:
	<StructureSection load='6rji' size='340' side='right'caption='[[6rji]], [[Resolution\|resolution]] 1.48Å' scene=''>		<StructureSection load='6rji' size='340' side='right'caption='[[6rji]], [[Resolution\|resolution]] 1.48Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Staa8 Staa8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RJI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RJI FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~efp~~, ~~SAOUHSC_01625 (~~[~~https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=93061 STAA8])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.48Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rji OCA], [https://pdbe.org/6rji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rji RCSB], [https://www.ebi.ac.uk/pdbsum/6rji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rji ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rji OCA], [https://pdbe.org/6rji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rji RCSB], [https://www.ebi.ac.uk/pdbsum/6rji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rji ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/EFP_STAA8 EFP_STAA8]] Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.	+	[https://www.uniprot.org/uniprot/EFP_STAA8 EFP_STAA8] Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Staa8~~]]	+	[[Category: Staphylococcus aureus subsp. aureus NCTC 8325]]
-	[[Category: Fatkhullin~~, B F~~]]	+	[[Category: Fatkhullin BF]]
-	[[Category: Gabdulkhakov~~, A G~~]]	+	[[Category: Gabdulkhakov AG]]
-	[[Category: Golubev~~, A A~~]]	+	[[Category: Golubev AA]]
-	[[Category: Khusainov~~, I S~~]]	+	[[Category: Khusainov IS]]
-	[[Category: Usachev~~, K S~~]]	+	[[Category: Usachev KS]]
-	[[Category: Validov~~, S Z~~]]	+	[[Category: Validov SZ]]
-	[[Category: Yusupov~~, M M~~]]	+	[[Category: Yusupov MM]]
-	[[Category: Yusupova, G]]	+	[[Category: Yusupova G]]
-	~~[[Category: Ef-p]]~~	+
-	~~[[Category: Efp]]~~	+
-	~~[[Category: Elongation factor p]]~~	+
-	~~[[Category: Translation~~]]	+

OCA at 15:25, 8 June 2021

OCA — Tue, 08 Jun 2021 15:25:47 GMT

←Older revision		Revision as of 15:25, 8 June 2021
Line 3:		Line 3:
	<StructureSection load='6rji' size='340' side='right'caption='[[6rji]], [[Resolution\|resolution]] 1.48Å' scene=''>		<StructureSection load='6rji' size='340' side='right'caption='[[6rji]], [[Resolution\|resolution]] 1.48Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rji]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6RJI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RJI FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">efp, SAOUHSC_01625 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93061 STAA8])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">efp, SAOUHSC_01625 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93061 STAA8])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6rji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rji OCA], [~~http~~://pdbe.org/6rji PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6rji RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6rji PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6rji ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rji OCA], [https://pdbe.org/6rji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rji RCSB], [https://www.ebi.ac.uk/pdbsum/6rji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rji ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/EFP_STAA8 EFP_STAA8]] Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.	+	[[https://www.uniprot.org/uniprot/EFP_STAA8 EFP_STAA8]] Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 6rji" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6rji" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Elongation factor 3D structures\|Elongation factor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:37, 3 June 2020

OCA — Wed, 03 Jun 2020 06:37:17 GMT

←Older revision		Revision as of 06:37, 3 June 2020
Line 3:		Line 3:
	<StructureSection load='6rji' size='340' side='right'caption='[[6rji]], [[Resolution\|resolution]] 1.48Å' scene=''>		<StructureSection load='6rji' size='340' side='right'caption='[[6rji]], [[Resolution\|resolution]] 1.48Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rji]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJI OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6RJI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rji]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RJI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6rji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rji OCA], [http://pdbe.org/6rji PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rji RCSB], [http://www.ebi.ac.uk/pdbsum/6rji PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rji ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">efp, SAOUHSC_01625 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93061 STAA8])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rji OCA], [http://pdbe.org/6rji PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rji RCSB], [http://www.ebi.ac.uk/pdbsum/6rji PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rji ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Staa8]]
	[[Category: Fatkhullin, B F]]		[[Category: Fatkhullin, B F]]
	[[Category: Gabdulkhakov, A G]]		[[Category: Gabdulkhakov, A G]]

OCA at 09:19, 1 April 2020

OCA — Wed, 01 Apr 2020 09:19:51 GMT

←Older revision		Revision as of 09:19, 1 April 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6rji is ~~ON HOLD~~	+	==X-ray structure of the elongation factor P of S. aureus==
		+	<StructureSection load='6rji' size='340' side='right'caption='[[6rji]], [[Resolution\|resolution]] 1.48Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6rji]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJI FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rji OCA], [http://pdbe.org/6rji PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rji RCSB], [http://www.ebi.ac.uk/pdbsum/6rji PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rji ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/EFP_STAA8 EFP_STAA8]] Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Elongation factor P (EF-P) is a translation protein factor that plays an important role in specialized translation of consecutive proline amino acid motifs. EF-P is an essential protein for cell fitness in native environmental conditions. It regulates synthesis of proteins involved in bacterial motility, environmental adaptation and bacterial virulence, thus making EF-P a potential drug target. In the present study, we determined the solution and crystal structure of EF-P from the pathogenic bacteria Staphylococcus aureus at 1.48 A resolution. The structure can serve as a platform for structure-based drug design of novel antibiotics to combat the growing antibiotic resistance of S. aureus.

-	~~Authors: Fatkhullin, B.F~~., Golubev, A.A., ~~Gabdulkhakov~~, A~~.G.~~, Khusainov, I~~.S.~~, Validov, S~~.Z.~~, ~~Usachev~~, K.S.~~, Yusupova, G~~., ~~Yusupov, M~~.M.	+	NMR and crystallographic structural studies of the Elongation factor P from Staphylococcus aureus.,Golubev A, Fatkhullin B, Gabdulkhakov A, Bikmullin A, Nurullina L, Garaeva N, Islamov D, Klochkova E, Klochkov V, Aganov A, Khusainov I, Validov S, Yusupova G, Yusupov M, Usachev K Eur Biophys J. 2020 Mar 9. pii: 10.1007/s00249-020-01428-x. doi:, 10.1007/s00249-020-01428-x. PMID:32152681<ref>PMID:32152681</ref>

-	~~Description: X-ray structure~~ of the ~~elongation factor P of~~ S. ~~aureus~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: Gabdulkhakov, A.G]]	+	<div class="pdbe-citations 6rji" style="background-color:#fffaf0;"></div>
-	[[Category: Golubev, A.A]]	+	== References ==
-	[[Category: Khusainov, I.S]]	+	<references/>
-	[[Category: ~~Fatkhullin~~, ~~B.F~~]]	+	__TOC__
-	[[Category: ~~Yusupov~~, ~~M.M]]~~	+	</StructureSection>
-	~~[[Category: Usachev, K.~~S]]	+	[[Category: Large Structures]]
-	[[Category: ~~Validov~~, ~~S.Z~~]]	+	[[Category: Fatkhullin, B F]]
		+	[[Category: Gabdulkhakov, A G]]
		+	[[Category: Golubev, A A]]
		+	[[Category: Khusainov, I S]]
		+	[[Category: Usachev, K S]]
		+	[[Category: Validov, S Z]]
		+	[[Category: Yusupov, M M]]
	[[Category: Yusupova, G]]		[[Category: Yusupova, G]]
		+	[[Category: Ef-p]]
		+	[[Category: Efp]]
		+	[[Category: Elongation factor p]]
		+	[[Category: Translation]]

OCA: Protected "6rji" [edit=sysop:move=sysop]

OCA — Fri, 10 May 2019 08:20:24 GMT

Protected "6rji" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:20, 10 May 2019

OCA: New page: '''Unreleased structure''' The entry 6rji is ON HOLD Authors: Fatkhullin, B.F., Golubev, A.A., Gabdulkhakov, A.G., Khusainov, I.S., Validov, S.Z., Usachev, K.S., Yusupova, G., Yusupov, ...

OCA — Fri, 10 May 2019 08:20:21 GMT

New page: '''Unreleased structure''' The entry 6rji is ON HOLD Authors: Fatkhullin, B.F., Golubev, A.A., Gabdulkhakov, A.G., Khusainov, I.S., Validov, S.Z., Usachev, K.S., Yusupova, G., Yusupov, ...

New page

'''Unreleased structure'''

The entry 6rji is ON HOLD

Authors: Fatkhullin, B.F., Golubev, A.A., Gabdulkhakov, A.G., Khusainov, I.S., Validov, S.Z., Usachev, K.S., Yusupova, G., Yusupov, M.M.

Description: X-ray structure of the elongation factor P of S. aureus
[[Category: Unreleased Structures]]
[[Category: Gabdulkhakov, A.G]]
[[Category: Golubev, A.A]]
[[Category: Khusainov, I.S]]
[[Category: Fatkhullin, B.F]]
[[Category: Yusupov, M.M]]
[[Category: Usachev, K.S]]
[[Category: Validov, S.Z]]
[[Category: Yusupova, G]]