6rjo - Revision history

OCA at 12:21, 24 January 2024

OCA — Wed, 24 Jan 2024 12:21:50 GMT

←Older revision		Revision as of 12:21, 24 January 2024
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	<StructureSection load='6rjo' size='340' side='right'caption='[[6rjo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='6rjo' size='340' side='right'caption='[[6rjo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rjo]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Agrobacterium_tumefaciens_a6~~ Agrobacterium tumefaciens a6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6RJO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rjo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_tumefaciens_A6 Agrobacterium tumefaciens A6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RJO FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=SA0:2-(HYDROXYMETHYL)PHENYL+BETA-D-GLUCOPYRANOSIDE'>SA0</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.804Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">sghA ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=1453998 Agrobacterium tumefaciens A6])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SA0:2-(HYDROXYMETHYL)PHENYL+BETA-D-GLUCOPYRANOSIDE'>SA0</scene></td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks'>[http~~:~~//en.wikipedia.org/wiki/Beta~~-~~glucosidase Beta~~-~~glucosidase], with EC number [http://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21]~~ </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjo OCA], [https://pdbe.org/6rjo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rjo RCSB], [https://www.ebi.ac.uk/pdbsum/6rjo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjo ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6rjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjo OCA], [~~http~~://pdbe.org/6rjo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6rjo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6rjo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjo ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A2I4PGZ0_RHIRD A0A2I4PGZ0_RHIRD]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6rjo" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6rjo" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-glucosidase 3D structures\|Beta-glucosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Agrobacterium tumefaciens ~~a6]]~~	+	[[Category: Agrobacterium tumefaciens A6]]
-	~~[[Category: Beta-glucosidase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chang~~, C Q~~]]	+	[[Category: Chang CQ]]
-	[[Category: Gao~~, Y G~~]]	+	[[Category: Gao YG]]
-	[[Category: Wang, C]]	+	[[Category: Wang C]]
-	[[Category: Ye~~, F Z~~]]	+	[[Category: Ye FZ]]
-	[[Category: Zhang~~, L H]]~~	+	[[Category: Zhang LH]]
-	~~[[Category: Agrobacterium]]~~	+
-	~~[[Category: Chemical signaling]]~~	+
-	~~[[Category: Glucosidase]]~~	+
-	~~[[Category: Host-pathogen interaction]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Sucrose~~]]	+

OCA at 08:09, 23 October 2019

OCA — Wed, 23 Oct 2019 08:09:03 GMT

←Older revision		Revision as of 08:09, 23 October 2019
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	<StructureSection load='6rjo' size='340' side='right'caption='[[6rjo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='6rjo' size='340' side='right'caption='[[6rjo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rjo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rjo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens_a6 Agrobacterium tumefaciens a6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SA0:2-(HYDROXYMETHYL)PHENYL+BETA-D-GLUCOPYRANOSIDE'>SA0</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SA0:2-(HYDROXYMETHYL)PHENYL+BETA-D-GLUCOPYRANOSIDE'>SA0</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sghA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1453998 Agrobacterium tumefaciens A6])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjo OCA], [http://pdbe.org/6rjo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rjo RCSB], [http://www.ebi.ac.uk/pdbsum/6rjo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjo OCA], [http://pdbe.org/6rjo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rjo RCSB], [http://www.ebi.ac.uk/pdbsum/6rjo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjo ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	It is highly intriguing how bacterial pathogens can quickly shut down energy-costly infection machinery once successful infection is established. This study depicts that mutation of repressor SghR increases the expression of hydrolase SghA in Agrobacterium tumefaciens, which releases plant defense signal salicylic acid (SA) from its storage form SA beta-glucoside (SAG). Addition of SA substantially reduces gene expression of bacterial virulence. Bacterial vir genes and sghA are differentially transcribed at early and later infection stages, respectively. Plant metabolite sucrose is a signal ligand that inactivates SghR and consequently induces sghA expression. Disruption of sghA leads to increased vir expression in planta and enhances tumor formation whereas mutation of sghR decreases vir expression and tumor formation. These results depict a remarkable mechanism by which A. tumefaciens taps on the reserved pool of plant signal SA to reprogram its virulence upon establishment of infection.
		+
		+	Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals.,Wang C, Ye F, Chang C, Liu X, Wang J, Wang J, Yan XF, Fu Q, Zhou J, Chen S, Gao YG, Zhang LH Proc Natl Acad Sci U S A. 2019 Oct 11. pii: 1903695116. doi:, 10.1073/pnas.1903695116. PMID:31604827<ref>PMID:31604827</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6rjo" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Agrobacterium tumefaciens a6]]
	[[Category: Beta-glucosidase]]		[[Category: Beta-glucosidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 05:24, 10 October 2019

OCA — Thu, 10 Oct 2019 05:24:40 GMT

←Older revision		Revision as of 05:24, 10 October 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6rjo is ~~ON HOLD~~	+	==Complex structure of virulence factor SghA with its substrate analog salicin==
-		+	<StructureSection load='6rjo' size='340' side='right'caption='[[6rjo]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~Authors~~: Ye, F.Z., ~~Wang, C~~., ~~Chang~~, C.Q., ~~Zhang, L~~.H., ~~Gao, Y~~.G.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6rjo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJO FirstGlance]. <br>
-	~~Description~~: ~~Complex structure of virulence factor SghA with its substrate analog salicin~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SA0:2-(HYDROXYMETHYL)PHENYL+BETA-D-GLUCOPYRANOSIDE'>SA0</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>
-	[[Category: Gao, Y.G]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjo OCA], [http://pdbe.org/6rjo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rjo RCSB], [http://www.ebi.ac.uk/pdbsum/6rjo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjo ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-glucosidase]]
		+	[[Category: Large Structures]]
		+	[[Category: Chang, C Q]]
		+	[[Category: Gao, Y G]]
	[[Category: Wang, C]]		[[Category: Wang, C]]
-	[[Category: ~~Chang~~, ~~C.Q~~]]	+	[[Category: Ye, F Z]]
-	[[Category: Ye, ~~F.Z~~]]	+	[[Category: Zhang, L H]]
-	[[Category: ~~Zhang, L.H~~]]	+	[[Category: Agrobacterium]]
		+	[[Category: Chemical signaling]]
		+	[[Category: Glucosidase]]
		+	[[Category: Host-pathogen interaction]]
		+	[[Category: Hydrolase]]
		+	[[Category: Sucrose]]

OCA: Protected "6rjo" [edit=sysop:move=sysop]

OCA — Fri, 10 May 2019 08:21:55 GMT

Protected "6rjo" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:21, 10 May 2019

OCA: New page: '''Unreleased structure''' The entry 6rjo is ON HOLD Authors: Ye, F.Z., Wang, C., Chang, C.Q., Zhang, L.H., Gao, Y.G. Description: Complex structure of virulence factor SghA with its s...

OCA — Fri, 10 May 2019 08:21:53 GMT

New page: '''Unreleased structure''' The entry 6rjo is ON HOLD Authors: Ye, F.Z., Wang, C., Chang, C.Q., Zhang, L.H., Gao, Y.G. Description: Complex structure of virulence factor SghA with its s...

New page

'''Unreleased structure'''

The entry 6rjo is ON HOLD

Authors: Ye, F.Z., Wang, C., Chang, C.Q., Zhang, L.H., Gao, Y.G.

Description: Complex structure of virulence factor SghA with its substrate analog salicin
[[Category: Unreleased Structures]]
[[Category: Gao, Y.G]]
[[Category: Wang, C]]
[[Category: Chang, C.Q]]
[[Category: Ye, F.Z]]
[[Category: Zhang, L.H]]