6rjv - Revision history

OCA at 12:22, 24 January 2024

OCA — Wed, 24 Jan 2024 12:22:00 GMT

←Older revision		Revision as of 12:22, 24 January 2024
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	<StructureSection load='6rjv' size='340' side='right'caption='[[6rjv]], [[Resolution\|resolution]] 3.21Å' scene=''>		<StructureSection load='6rjv' size='340' side='right'caption='[[6rjv]], [[Resolution\|resolution]] 3.21Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rjv]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6RJV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rjv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RJV FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.21Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6rjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjv OCA], [~~http~~://pdbe.org/6rjv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6rjv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6rjv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjv ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjv OCA], [https://pdbe.org/6rjv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rjv RCSB], [https://www.ebi.ac.uk/pdbsum/6rjv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjv ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.	+	[https://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6rjv" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6rjv" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Albumin 3D structures\|Albumin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ferraro, G]]	+	[[Category: Ferraro G]]
-	[[Category: Giorgio, A]]	+	[[Category: Giorgio A]]
-	[[Category: Merlino, A]]	+	[[Category: Merlino A]]
-	~~[[Category: Transport protein~~]]	+

OCA at 16:44, 14 August 2019

OCA — Wed, 14 Aug 2019 16:44:53 GMT

←Older revision		Revision as of 16:44, 14 August 2019
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-	'''Unreleased structure'''

-	The ~~entry~~ 6rjv is ~~ON HOLD~~	+	==The X-ray structure of the Gold/Serum Albumin adduct obtained upon reaction of the protein with AuL12, a gold(III) dithiocarbamate complex==
		+	<StructureSection load='6rjv' size='340' side='right'caption='[[6rjv]], [[Resolution\|resolution]] 3.21Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6rjv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJV FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rjv OCA], [http://pdbe.org/6rjv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rjv RCSB], [http://www.ebi.ac.uk/pdbsum/6rjv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rjv ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The medicinal gold(III) dithiocarbamato complex AuL12 forms a stable adduct with bovine serum albumin. The crystal structure reveals that a single gold(I) center is bound to Cys34, with the dithiocarbamato ligand being released. To the best of our knowledge, this is the first structure for a gold adduct of serum albumin.

-	~~Authors: Merlino~~, A., ~~Giorgio~~, A., Ferraro, G.	+	Structural Characterization of a Gold/Serum Albumin Complex.,Pratesi A, Cirri D, Fregona D, Ferraro G, Giorgio A, Merlino A, Messori L Inorg Chem. 2019 Jul 30. doi: 10.1021/acs.inorgchem.9b01900. PMID:31361466<ref>PMID:31361466</ref>

-	~~Description: The X-ray structure of the Gold~~/~~Serum Albumin adduct obtained upon reaction of the protein with AuL12~~, a ~~gold(III) dithiocarbamate complex~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6rjv" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bos taurus]]
		+	[[Category: Large Structures]]
	[[Category: Ferraro, G]]		[[Category: Ferraro, G]]
-	[[Category: Merlino, A]]
	[[Category: Giorgio, A]]		[[Category: Giorgio, A]]
		+	[[Category: Merlino, A]]
		+	[[Category: Transport protein]]

OCA: Protected "6rjv" [edit=sysop:move=sysop]

OCA — Fri, 10 May 2019 08:23:20 GMT

Protected "6rjv" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:23, 10 May 2019

OCA: New page: '''Unreleased structure''' The entry 6rjv is ON HOLD Authors: Merlino, A., Giorgio, A., Ferraro, G. Description: The X-ray structure of the Gold/Serum Albumin adduct obtained upon reac...

OCA — Fri, 10 May 2019 08:23:17 GMT

New page: '''Unreleased structure''' The entry 6rjv is ON HOLD Authors: Merlino, A., Giorgio, A., Ferraro, G. Description: The X-ray structure of the Gold/Serum Albumin adduct obtained upon reac...

New page

'''Unreleased structure'''

The entry 6rjv is ON HOLD

Authors: Merlino, A., Giorgio, A., Ferraro, G.

Description: The X-ray structure of the Gold/Serum Albumin adduct obtained upon reaction of the protein with AuL12, a gold(III) dithiocarbamate complex
[[Category: Unreleased Structures]]
[[Category: Ferraro, G]]
[[Category: Merlino, A]]
[[Category: Giorgio, A]]