6rqk - Revision history

OCA at 12:26, 24 January 2024

OCA — Wed, 24 Jan 2024 12:26:28 GMT

←Older revision		Revision as of 12:26, 24 January 2024
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	<StructureSection load='6rqk' size='340' side='right'caption='[[6rqk]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='6rqk' size='340' side='right'caption='[[6rqk]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rqk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RQK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6RQK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rqk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens_str._13 Clostridium perfringens str. 13]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RQK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MVL:(5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL'>MVL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6rqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rqk OCA], [~~http~~://pdbe.org/6rqk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6rqk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6rqk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6rqk ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MVL:(5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL'>MVL</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rqk OCA], [https://pdbe.org/6rqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rqk RCSB], [https://www.ebi.ac.uk/pdbsum/6rqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rqk ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8XNB2_CLOPE Q8XNB2_CLOPE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6rqk" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6rqk" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Mannosidase 3D structures\|Mannosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Clostridium perfringens str. 13]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Davies~~, G J~~]]	+	[[Category: Davies GJ]]
-	[[Category: Males, A]]	+	[[Category: Males A]]
-	~~[[Category: Carbohydrate]]~~	+
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Glycoside hydrolase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Inhibitor~~]]	+

OCA at 15:42, 28 August 2019

OCA — Wed, 28 Aug 2019 15:42:46 GMT

←Older revision		Revision as of 15:42, 28 August 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6rqk is ~~ON HOLD~~	+	==Crystal structure of GH125 1,6-alpha-mannosidase from Clostridium perfringens in complex with mannoimidazole==
		+	<StructureSection load='6rqk' size='340' side='right'caption='[[6rqk]], [[Resolution\|resolution]] 1.85Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6rqk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RQK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RQK FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MVL:(5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL'>MVL</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rqk OCA], [http://pdbe.org/6rqk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rqk RCSB], [http://www.ebi.ac.uk/pdbsum/6rqk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rqk ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Enzyme transition-state mimics can act as powerful inhibitors and allow structural studies that report on the conformation of the transition-state. Here, mannoimidazole, a mimic of the transition state of mannosidase catalyzed hydrolysis of mannosides, is shown to bind in a B2,5 conformation on the Clostridium perfringens GH125 alpha-1,6-mannosidase, providing additional evidence of a OS2-B2,5-1S5 conformational itinerary for enzymes of this family.

-	~~Authors~~:	+	Distortion of mannoimidazole supports a B2,5 boat transition state for the family GH125 alpha-1,6-mannosidase from Clostridium perfringens.,Males A, Speciale G, Williams SJ, Davies GJ Org Biomol Chem. 2019 Aug 13. doi: 10.1039/c9ob01161g. PMID:31407758<ref>PMID:31407758</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6rqk" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Davies, G J]]
		+	[[Category: Males, A]]
		+	[[Category: Carbohydrate]]
		+	[[Category: Complex]]
		+	[[Category: Glycoside hydrolase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inhibitor]]

OCA: Protected "6rqk" [edit=sysop:move=sysop]

OCA — Wed, 22 May 2019 04:22:04 GMT

Protected "6rqk" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:22, 22 May 2019

OCA: New page: '''Unreleased structure''' The entry 6rqk is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 22 May 2019 04:22:03 GMT

New page: '''Unreleased structure''' The entry 6rqk is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6rqk is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]