6rsl - Revision history

OCA at 12:27, 24 January 2024

OCA — Wed, 24 Jan 2024 12:27:37 GMT

←Older revision		Revision as of 12:27, 24 January 2024
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	<StructureSection load='6rsl' size='340' side='right'caption='[[6rsl]], [[Resolution\|resolution]] 1.99Å' scene=''>		<StructureSection load='6rsl' size='340' side='right'caption='[[6rsl]], [[Resolution\|resolution]] 1.99Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rsl]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Baker's_yeast Baker's yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RSL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6RSL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rsl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RSL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EVB:sulfonato-calix[8]arene'>EVB</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.988Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6gd9\|6gd9]], [[6gda\|6gda]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EVB:sulfonato-calix[8]arene'>EVB</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYC1, YJR048W, J1653 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rsl OCA], [https://pdbe.org/6rsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rsl RCSB], [https://www.ebi.ac.uk/pdbsum/6rsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rsl ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6rsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rsl OCA], [~~http~~://pdbe.org/6rsl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6rsl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6rsl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6rsl ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CYC1_YEAST CYC1_YEAST]] Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	+	[https://www.uniprot.org/uniprot/CYC1_YEAST CYC1_YEAST] Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6rsl" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6rsl" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cytochrome C 3D structures\|Cytochrome C 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Baker's yeast]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Crowley, P B~~]]	+	[[Category: Saccharomyces cerevisiae S288C]]
-	[[Category: ~~Engilberge, S~~]]	+	[[Category: Crowley PB]]
-	[[Category: ~~Calixarene]]~~	+	[[Category: Engilberge S]]
-	~~[[Category: Cytc]]~~	+
-	~~[[Category: Molecular glue]]~~	+
-	~~[[Category: Molecular switch]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Polyamine]]~~	+
-	~~[[Category: Spermine]]~~	+
-	~~[[Category: Supramolecular chemistry~~]]	+

OCA at 08:10, 23 October 2019

OCA — Wed, 23 Oct 2019 08:10:39 GMT

←Older revision		Revision as of 08:10, 23 October 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6rsl is ~~ON HOLD until Paper~~ Publication	+	==Cytochrome c co-crystallized with 10 eq. sulfonato-calix[8]arene and 25 eq. spermine (dry-coating method) - structure III==
		+	<StructureSection load='6rsl' size='340' side='right'caption='[[6rsl]], [[Resolution\|resolution]] 1.99Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6rsl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RSL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RSL FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EVB:sulfonato-calix[8]arene'>EVB</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6gd9\|6gd9]], [[6gda\|6gda]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CYC1, YJR048W, J1653 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rsl OCA], [http://pdbe.org/6rsl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rsl RCSB], [http://www.ebi.ac.uk/pdbsum/6rsl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rsl ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CYC1_YEAST CYC1_YEAST]] Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein crystals with their precise, periodic array of functional building blocks have potential applications in biomaterials, sensing, and catalysis. This paper describes how a highly porous crystalline framework of a cationic redox protein and an anionic macrocycle can be modulated by a small cationic effector. Ternary composites of protein ( approximately 13 kDa), calix[8]arene ( approximately 1.5 kDa), and effector ( approximately 0.2 kDa) formed distinct crystalline architectures, dependent on the effector concentration and the crystallization technique. A combination of X-ray crystallography and density functional theory (DFT) calculations was used to decipher the framework variations, which appear to be dependent on a calixarene conformation change mediated by the effector. This "switch" calixarene was observed in three states, each of which is associated with a different interaction network. Two structures obtained by co-crystallization with the effector contained an additional protein "pillar", resulting in framework duplication and decreased porosity. These results suggest how protein assembly can be engineered by supramolecular host-guest interactions.

-	~~Authors: Engilberge~~, S., ~~Crowley~~, P.B.	+	Tuning Protein Frameworks via Auxiliary Supramolecular Interactions.,Engilberge S, Rennie ML, Dumont E, Crowley PB ACS Nano. 2019 Sep 24;13(9):10343-10350. doi: 10.1021/acsnano.9b04115. Epub 2019 , Sep 10. PMID:31490058<ref>PMID:31490058</ref>

-	~~Description: Cytochrome c co-crystallized with 10 eq~~. ~~sulfonato-calix[8]arene and 25 eq~~. ~~spermine (dry~~-~~coating method)~~ -~~structure III~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: Crowley, P.B]]	+	<div class="pdbe-citations 6rsl" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Baker's yeast]]
		+	[[Category: Large Structures]]
		+	[[Category: Crowley, P B]]
	[[Category: Engilberge, S]]		[[Category: Engilberge, S]]
		+	[[Category: Calixarene]]
		+	[[Category: Cytc]]
		+	[[Category: Molecular glue]]
		+	[[Category: Molecular switch]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Polyamine]]
		+	[[Category: Spermine]]
		+	[[Category: Supramolecular chemistry]]

OCA at 21:17, 5 June 2019

OCA — Wed, 05 Jun 2019 21:17:43 GMT

←Older revision		Revision as of 21:17, 5 June 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6rsl is ON HOLD	+	The entry 6rsl is ON HOLD until Paper Publication

	Authors: Engilberge, S., Crowley, P.B.		Authors: Engilberge, S., Crowley, P.B.

OCA: Protected "6rsl" [edit=sysop:move=sysop]

OCA — Wed, 29 May 2019 04:46:43 GMT

Protected "6rsl" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:46, 29 May 2019

OCA: New page: '''Unreleased structure''' The entry 6rsl is ON HOLD Authors: Engilberge, S., Crowley, P.B. Description: Cytochrome c co-crystallized with 10 eq. sulfonato-calix[8]arene and 25 eq. spe...

OCA — Wed, 29 May 2019 04:46:42 GMT

New page: '''Unreleased structure''' The entry 6rsl is ON HOLD Authors: Engilberge, S., Crowley, P.B. Description: Cytochrome c co-crystallized with 10 eq. sulfonato-calix[8]arene and 25 eq. spe...

New page

'''Unreleased structure'''

The entry 6rsl is ON HOLD

Authors: Engilberge, S., Crowley, P.B.

Description: Cytochrome c co-crystallized with 10 eq. sulfonato-calix[8]arene and 25 eq. spermine (dry-coating method) -structure III
[[Category: Unreleased Structures]]
[[Category: Crowley, P.B]]
[[Category: Engilberge, S]]