6rvr - Revision history

OCA at 10:13, 22 May 2024

OCA — Wed, 22 May 2024 10:13:14 GMT

←Older revision		Revision as of 10:13, 22 May 2024
Line 3:		Line 3:
	<SX load='6rvr' size='340' side='right' viewer='molstar' caption='[[6rvr]], [[Resolution\|resolution]] 3.46Å' scene=''>		<SX load='6rvr' size='340' side='right' viewer='molstar' caption='[[6rvr]], [[Resolution\|resolution]] 3.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rvr]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ebvg Ebvg~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RVR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6RVR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rvr]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RVR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RVR FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~BBRF1 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=10376 EBVG])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.46Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rvr OCA], [~~http~~://pdbe.org/6rvr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6rvr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6rvr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6rvr ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rvr OCA], [https://pdbe.org/6rvr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rvr RCSB], [https://www.ebi.ac.uk/pdbsum/6rvr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rvr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~A0A0B6VPI0_EBVG A0A0B6VPI0_EBVG]~~] Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging. Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid. Binds to the molecular motor that translocates the viral DNA, termed terminase.[HAMAP-Rule:MF_04012]	+	[https://www.uniprot.org/uniprot/PORTL_EBVG PORTL_EBVG] Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging. Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid. Binds to the molecular motor that translocates the viral DNA, termed terminase.[HAMAP-Rule:MF_04012]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Portal protein\|Portal protein]]	+	*[[Portal protein 3D structures\|Portal protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: ~~Ebvg~~]]	+	[[Category: Human gammaherpesvirus 4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Carrascosa~~, J L~~]]	+	[[Category: Carrascosa JL]]
-	[[Category: Coll, M]]	+	[[Category: Coll M]]
-	[[Category: Cuervo, A]]	+	[[Category: Cuervo A]]
-	[[Category: Fabrega-Ferrer, M]]	+	[[Category: Fabrega-Ferrer M]]
-	[[Category: Machon, C]]	+	[[Category: Machon C]]
-	[[Category: Stuart~~, D I~~]]	+	[[Category: Stuart DI]]
-	[[Category: Zhou, D]]	+	[[Category: Zhou D]]
-	~~[[Category: Dna packaging]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 05:51, 11 April 2020

OCA — Sat, 11 Apr 2020 05:51:40 GMT

←Older revision		Revision as of 05:51, 11 April 2020
Line 3:		Line 3:
	<SX load='6rvr' size='340' side='right' viewer='molstar' caption='[[6rvr]], [[Resolution\|resolution]] 3.46Å' scene=''>		<SX load='6rvr' size='340' side='right' viewer='molstar' caption='[[6rvr]], [[Resolution\|resolution]] 3.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6rvr]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Ebvg Ebvg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RVR OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6RVR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rvr]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Ebvg Ebvg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RVR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RVR FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBRF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10376 EBVG])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBRF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10376 EBVG])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rvr OCA], [http://pdbe.org/6rvr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rvr RCSB], [http://www.ebi.ac.uk/pdbsum/6rvr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rvr ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rvr OCA], [http://pdbe.org/6rvr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rvr RCSB], [http://www.ebi.ac.uk/pdbsum/6rvr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rvr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 00:25, 7 March 2020

OCA — Sat, 07 Mar 2020 00:25:01 GMT

←Older revision		Revision as of 00:25, 7 March 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6rvr is ~~ON HOLD~~	+	==Atomic structure of the Epstein-Barr portal, structure I==
		+	<SX load='6rvr' size='340' side='right' viewer='molstar' caption='[[6rvr]], [[Resolution\|resolution]] 3.46Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6rvr]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Ebvg Ebvg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RVR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RVR FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBRF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10376 EBVG])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rvr OCA], [http://pdbe.org/6rvr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rvr RCSB], [http://www.ebi.ac.uk/pdbsum/6rvr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rvr ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/A0A0B6VPI0_EBVG A0A0B6VPI0_EBVG]] Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging. Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid. Binds to the molecular motor that translocates the viral DNA, termed terminase.[HAMAP-Rule:MF_04012]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Herpesviridae is a vast family of enveloped DNA viruses that includes eight distinct human pathogens, responsible for diseases that range from almost asymptomatic to severe and life-threatening. Epstein-Barr virus infects B-cells and epithelial cells, causing infectious mononucleosis, as well as a number of cancers. Epstein-Barr infection cannot be cured since neither vaccine nor antiviral drug treatments are available. All herpesviruses contain a linear double-stranded DNA genome, enclosed within an icosahedral capsid. Viral portal protein plays a key role in the procapsid assembly and DNA packaging. The portal is the entrance and exit pore for the viral genome, making it an attractive pharmacological target for the development of new antivirals. Here we present the atomic structure of the portal protein of Epstein-Barr virus, solved by cryo-electron microscopy at 3.5 A resolution. The detailed architecture of this protein suggests that it plays a functional role in DNA retention during packaging.

-	~~Authors~~:	+	Atomic structure of the Epstein-Barr virus portal.,Machon C, Fabrega-Ferrer M, Zhou D, Cuervo A, Carrascosa JL, Stuart DI, Coll M Nat Commun. 2019 Aug 29;10(1):3891. doi: 10.1038/s41467-019-11706-8. PMID:31467275<ref>PMID:31467275</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6rvr" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Portal protein\|Portal protein]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</SX>
		+	[[Category: Ebvg]]
		+	[[Category: Large Structures]]
		+	[[Category: Carrascosa, J L]]
		+	[[Category: Coll, M]]
		+	[[Category: Cuervo, A]]
		+	[[Category: Fabrega-Ferrer, M]]
		+	[[Category: Machon, C]]
		+	[[Category: Stuart, D I]]
		+	[[Category: Zhou, D]]
		+	[[Category: Dna packaging]]
		+	[[Category: Viral protein]]

OCA: Protected "6rvr" [edit=sysop:move=sysop]

OCA — Wed, 12 Jun 2019 04:13:06 GMT

Protected "6rvr" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:13, 12 June 2019

OCA: New page: '''Unreleased structure''' The entry 6rvr is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 12 Jun 2019 04:13:05 GMT

New page: '''Unreleased structure''' The entry 6rvr is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6rvr is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]