6rzk - Revision history

OCA at 12:31, 24 January 2024

OCA — Wed, 24 Jan 2024 12:31:56 GMT

←Older revision		Revision as of 12:31, 24 January 2024
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	==Galectin-3C in complex with trifluoroaryltriazole monothiogalactoside derivative:3(Chlorine)==		==Galectin-3C in complex with trifluoroaryltriazole monothiogalactoside derivative:3(Chlorine)==
-	<StructureSection load='6rzk' size='340' side='right'caption='[[6rzk]]' scene=''>	+	<StructureSection load='6rzk' size='340' side='right'caption='[[6rzk]], [[Resolution\|resolution]] 1.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RZK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6RZK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6rzk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RZK FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6rzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rzk OCA], [~~http~~://pdbe.org/6rzk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6rzk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6rzk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6rzk ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.046Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KOZ:(2~{R},3~{R},4~{S},5~{R},6~{R})-2-(3-chlorophenyl)sulfanyl-6-(hydroxymethyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol'>KOZ</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rzk OCA], [https://pdbe.org/6rzk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rzk RCSB], [https://www.ebi.ac.uk/pdbsum/6rzk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rzk ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref>
		+
		+	==See Also==
		+	*[[Galectin 3D structures\|Galectin 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Kumar R]]		[[Category: Kumar R]]

OCA at 14:03, 8 July 2020

OCA — Wed, 08 Jul 2020 14:03:33 GMT

←Older revision		Revision as of 14:03, 8 July 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6rzk ~~is ON HOLD~~	+	==Galectin-3C in complex with trifluoroaryltriazole monothiogalactoside derivative:3(Chlorine)==
-		+	<StructureSection load='6rzk' size='340' side='right'caption='[[6rzk]]' scene=''>
-	~~Authors~~: ~~Kumar~~, R., ~~Verteramo~~, M.L., ~~Nilsson, U~~.J., ~~Logan, D~~.T.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RZK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RZK FirstGlance]. <br>
-	~~Description: Galectin-3C in complex with trifluoroaryltriazole monothiogalactoside derivative:3(Chlorine)~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rzk OCA], [http://pdbe.org/6rzk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rzk RCSB], [http://www.ebi.ac.uk/pdbsum/6rzk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rzk ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: ~~Logan, D.T~~]]	+	__TOC__
-	[[Category: ~~Verteramo, M.L~~]]	+	</StructureSection>
-	[[Category: ~~Kumar, R~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Nilsson, U.J~~]]	+	[[Category: Kumar R]]
		+	[[Category: Logan DT]]
		+	[[Category: Nilsson UJ]]
		+	[[Category: Verteramo ML]]

OCA: Protected "6rzk" [edit=sysop:move=sysop]

OCA — Wed, 19 Jun 2019 04:34:58 GMT

Protected "6rzk" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:34, 19 June 2019

OCA: New page: '''Unreleased structure''' The entry 6rzk is ON HOLD Authors: Kumar, R., Verteramo, M.L., Nilsson, U.J., Logan, D.T. Description: Galectin-3C in complex with trifluoroaryltriazole mono...

OCA — Wed, 19 Jun 2019 04:34:57 GMT

New page: '''Unreleased structure''' The entry 6rzk is ON HOLD Authors: Kumar, R., Verteramo, M.L., Nilsson, U.J., Logan, D.T. Description: Galectin-3C in complex with trifluoroaryltriazole mono...

New page

'''Unreleased structure'''

The entry 6rzk is ON HOLD

Authors: Kumar, R., Verteramo, M.L., Nilsson, U.J., Logan, D.T.

Description: Galectin-3C in complex with trifluoroaryltriazole monothiogalactoside derivative:3(Chlorine)
[[Category: Unreleased Structures]]
[[Category: Logan, D.T]]
[[Category: Verteramo, M.L]]
[[Category: Kumar, R]]
[[Category: Nilsson, U.J]]