6sbz - Revision history

OCA: Redirecting to 6sct

OCA — Wed, 22 Jan 2020 16:04:42 GMT

Redirecting to 6sct

←Older revision		Revision as of 16:04, 22 January 2020
Line 1:		Line 1:
-		+	#REDIRECT [[6sct]] This PDB entry is obsolete and replaced by 6sct
-	~~==Cryo-EM structure of the consensus triskelion hub of the clathrin coat complex==~~	+
-	~~<StructureSection load='6sbz' size='340' side='right'caption='~~[[~~6sbz]], [[Resolution\|resolution]] 4.69Å' scene=''>~~	+
-	~~== Structural highlights ==~~	+
-	~~<table><tr><td colspan='2'>[[6sbz~~]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SBZ FirstGlance]. <br>	+
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CLTC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG]), CLTB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sbz OCA], [http://pdbe.org/6sbz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sbz RCSB], [http://www.ebi.ac.uk/pdbsum/6sbz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sbz ProSAT]</span></td></tr>	+
-	~~</table>~~	+
-	~~== Function ==~~	+
-	~~[[http://www.uniprot.org/uniprot/C0MHR2_PIG C0MHR2_PIG]] Clathrin is the major protein of the polyhedral coat of coated pits~~ and ~~vesicles.[PIRNR:PIRNR002290] [[http://www.uniprot.org/uniprot/F1S398_PIG F1S398_PIG]] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.[RuleBase:RU363137]~~	+
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Clathrin forms diverse lattice and cage structures that change size and shape rapidly in response to the needs of eukaryotic cells during clathrin-mediated endocytosis and intracellular trafficking. We present the cryo-EM structure and molecular model of assembled porcine clathrin, providing insights into interactions that stabilize key elements of the clathrin lattice, namely, between adjacent heavy chains, at the light chain-heavy chain interface and within the trimerization domain. Furthermore, we report cryo-EM maps for five different clathrin cage architectures. Fitting structural models to three of these maps shows that their assembly requires only a limited range of triskelion leg conformations, yet inherent flexibility is required to maintain contacts. Analysis of the protein-protein interfaces shows remarkable conservation of contact sites despite architectural variation. These data reveal a universal mode of clathrin assembly that allows variable cage architecture and adaptation of coated vesicle size and shape during clathrin-mediated vesicular trafficking or endocytosis.	+
-		+
-	Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly.,Morris KL, Jones JR, Halebian M, Wu S, Baker M, Armache JP, Avila Ibarra A, Sessions RB, Cameron AD, Cheng Y, Smith CJ Nat Struct Mol Biol. 2019 Oct;26(10):890-898. doi: 10.1038/s41594-019-0292-0., Epub 2019 Oct 3. PMID:31582853<ref>PMID:31582853</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 6sbz" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+
-	~~__TOC__~~	+
-	~~</StructureSection>~~	+
-	~~[[Category: Large Structures]]~~	+
-	~~[[Category: Pig]]~~	+
-	~~[[Category: Cameron, A D]]~~	+
-	~~[[Category: Morris, K L]]~~	+
-	~~[[Category: Sessions, R]]~~	+
-	~~[[Category: Smith, C J]]~~	+
-	~~[[Category: Clathrin]]~~	+
-	~~[[Category: Coat protein]]~~	+
-	~~[[Category: Endocytosis]]~~	+
-	~~[[Category: Trafficking]]~~	+
-	~~[[Category: Transport protein]]~~	+

OCA at 08:49, 6 November 2019

OCA — Wed, 06 Nov 2019 08:49:21 GMT

←Older revision		Revision as of 08:49, 6 November 2019
Line 3:		Line 3:
	<StructureSection load='6sbz' size='340' side='right'caption='[[6sbz]], [[Resolution\|resolution]] 4.69Å' scene=''>		<StructureSection load='6sbz' size='340' side='right'caption='[[6sbz]], [[Resolution\|resolution]] 4.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6sbz]] is a 15 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SBZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6sbz]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SBZ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sbz OCA], [http://pdbe.org/6sbz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sbz RCSB], [http://www.ebi.ac.uk/pdbsum/6sbz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sbz ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CLTC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG]), CLTB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sbz OCA], [http://pdbe.org/6sbz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sbz RCSB], [http://www.ebi.ac.uk/pdbsum/6sbz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sbz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Pig]]
	[[Category: Cameron, A D]]		[[Category: Cameron, A D]]
	[[Category: Morris, K L]]		[[Category: Morris, K L]]

OCA at 06:02, 16 October 2019

OCA — Wed, 16 Oct 2019 06:02:19 GMT

←Older revision		Revision as of 06:02, 16 October 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6sbz is ~~ON HOLD~~	+	==Cryo-EM structure of the consensus triskelion hub of the clathrin coat complex==
		+	<StructureSection load='6sbz' size='340' side='right'caption='[[6sbz]], [[Resolution\|resolution]] 4.69Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6sbz]] is a 15 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SBZ FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sbz OCA], [http://pdbe.org/6sbz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sbz RCSB], [http://www.ebi.ac.uk/pdbsum/6sbz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sbz ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/C0MHR2_PIG C0MHR2_PIG]] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.[PIRNR:PIRNR002290] [[http://www.uniprot.org/uniprot/F1S398_PIG F1S398_PIG]] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.[RuleBase:RU363137]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Clathrin forms diverse lattice and cage structures that change size and shape rapidly in response to the needs of eukaryotic cells during clathrin-mediated endocytosis and intracellular trafficking. We present the cryo-EM structure and molecular model of assembled porcine clathrin, providing insights into interactions that stabilize key elements of the clathrin lattice, namely, between adjacent heavy chains, at the light chain-heavy chain interface and within the trimerization domain. Furthermore, we report cryo-EM maps for five different clathrin cage architectures. Fitting structural models to three of these maps shows that their assembly requires only a limited range of triskelion leg conformations, yet inherent flexibility is required to maintain contacts. Analysis of the protein-protein interfaces shows remarkable conservation of contact sites despite architectural variation. These data reveal a universal mode of clathrin assembly that allows variable cage architecture and adaptation of coated vesicle size and shape during clathrin-mediated vesicular trafficking or endocytosis.

-	~~Authors~~:	+	Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly.,Morris KL, Jones JR, Halebian M, Wu S, Baker M, Armache JP, Avila Ibarra A, Sessions RB, Cameron AD, Cheng Y, Smith CJ Nat Struct Mol Biol. 2019 Oct;26(10):890-898. doi: 10.1038/s41594-019-0292-0., Epub 2019 Oct 3. PMID:31582853<ref>PMID:31582853</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6sbz" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Cameron, A D]]
		+	[[Category: Morris, K L]]
		+	[[Category: Sessions, R]]
		+	[[Category: Smith, C J]]
		+	[[Category: Clathrin]]
		+	[[Category: Coat protein]]
		+	[[Category: Endocytosis]]
		+	[[Category: Trafficking]]
		+	[[Category: Transport protein]]

OCA: Protected "6sbz" [edit=sysop:move=sysop]

OCA — Wed, 31 Jul 2019 04:56:04 GMT

Protected "6sbz" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:56, 31 July 2019

OCA: New page: '''Unreleased structure''' The entry 6sbz is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 31 Jul 2019 04:56:02 GMT

New page: '''Unreleased structure''' The entry 6sbz is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6sbz is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]