6syj - Revision history

OCA at 10:41, 15 November 2023

OCA — Wed, 15 Nov 2023 10:41:54 GMT

←Older revision		Revision as of 10:41, 15 November 2023
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	<StructureSection load='6syj' size='340' side='right'caption='[[6syj]], [[Resolution\|resolution]] 0.81Å' scene=''>		<StructureSection load='6syj' size='340' side='right'caption='[[6syj]], [[Resolution\|resolution]] 0.81Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6syj]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SYJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6SYJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6syj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SYJ FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non~~-~~Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=2L6:(3S,6R,8AS)-5-OXO-1,2,3,8A-TETRAHYDROSPIRO[INDOLIZINE-6,2-PYRROLIDINE]-3-CARBOXYLIC+ACID'>2L6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 0.81Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6syj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6syj OCA], [~~http~~://pdbe.org/6syj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6syj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6syj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6syj ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2L6:(3S,6R,8AS)-5-OXO-1,2,3,8A-TETRAHYDROSPIRO[INDOLIZINE-6,2-PYRROLIDINE]-3-CARBOXYLIC+ACID'>2L6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6syj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6syj OCA], [https://pdbe.org/6syj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6syj RCSB], [https://www.ebi.ac.uk/pdbsum/6syj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6syj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Baumann, U]]	+	[[Category: Synthetic construct]]
-	[[Category: Gebauer~~, J M~~]]	+	[[Category: Baumann U]]
-	[[Category: Maassen, A]]	+	[[Category: Gebauer JM]]
-	[[Category: Schmalz, H G]]	+	[[Category: Maassen A]]
-	~~[[Category: Collagen model peptide]]~~	+	[[Category: Schmalz H-G]]
-	~~[[Category: Collagen stability]]~~	+
-	~~[[Category: Protein engineering]]~~	+
-	~~[[Category: Structural protein~~]]	+

OCA at 15:39, 29 January 2020

OCA — Wed, 29 Jan 2020 15:39:48 GMT

←Older revision		Revision as of 15:39, 29 January 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6syj is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of a ProM2 containing triple-helical collagen peptide.==
		+	<StructureSection load='6syj' size='340' side='right'caption='[[6syj]], [[Resolution\|resolution]] 0.81Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6syj]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SYJ FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=2L6:(3S,6R,8AS)-5-OXO-1,2,3,8A-TETRAHYDROSPIRO[INDOLIZINE-6,2-PYRROLIDINE]-3-CARBOXYLIC+ACID'>2L6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6syj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6syj OCA], [http://pdbe.org/6syj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6syj RCSB], [http://www.ebi.ac.uk/pdbsum/6syj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6syj ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Collagen model peptides (CMPs) serve as tools for under-standing stability and function of the collagen triple helix and have a potential for biomedical applications. In the past, inter-strand cross-linking or conformational preconditioning of proline units through stereoelectronic effects have been utilized in the design of stabilized CMPs. To further study the effects determining collagen triple helix stability we investigated a series of CMPs containing synthetic diproline-mimicking modules (ProMs), which are preorganized in a PPII helix-type conformation by a functionalizable intra-strand C2-bridge. Results of CD-based denaturation studies were correlated with calculated (DFT) conformational preferences of the ProM units revealing that the relative helix stability is mainly governed by an interplay of main chain preorganization, ring flip preference, adaptability and steric effects. Triple helix integrity was proven by crystal structure analysis and binding to HSP47.

-	~~Authors~~:	+	Triple Helix Stabilizing Effects in Collagen Model Peptides Containing PPII Helix-Preorganized Diproline Modules.,Schmalz HG, Maassen A, Gebauer J, Abraham ET, Grimm I, Neudorfl JM, Neundorf I, Baumann U Angew Chem Int Ed Engl. 2020 Jan 16. doi: 10.1002/anie.201914101. PMID:31944532<ref>PMID:31944532</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6syj" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Baumann, U]]
		+	[[Category: Gebauer, J M]]
		+	[[Category: Maassen, A]]
		+	[[Category: Schmalz, H G]]
		+	[[Category: Collagen model peptide]]
		+	[[Category: Collagen stability]]
		+	[[Category: Protein engineering]]
		+	[[Category: Structural protein]]

OCA at 04:24, 16 October 2019

OCA — Wed, 16 Oct 2019 04:24:22 GMT

←Older revision		Revision as of 04:24, 16 October 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6syj is ON HOLD	+	The entry 6syj is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6syj" [edit=sysop:move=sysop]

OCA — Thu, 10 Oct 2019 03:42:59 GMT

Protected "6syj" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:42, 10 October 2019

OCA: New page: '''Unreleased structure''' The entry 6syj is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 10 Oct 2019 03:42:57 GMT

New page: '''Unreleased structure''' The entry 6syj is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6syj is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]